Philadelphia Phillies vs Los Angeles Dodgers Prediction & Picks - MLB

Prediction published on 9/16/25, 6:15 PM  by Lou Aguila in MLB Picks

After squeaking out a 6-5 extra-inning win on Monday, the Philadelphia Phillies will go for two in a row against the Los Angeles Dodgers in Tuesday’s Game 2 of a highly crucial series at Dodger Stadium.

FanDuel has listed the Phillies as +102 underdogs ahead of Game 2 as they will be facing two-way star Shohei Ohtani, who surrendered zero in his last mound appearance.

Current Form:

The Phillies have locked up the NL East championship after posting a 90-61 record with still two weeks left in their regular-season schedule. Philadelphia has established itself as one of the top pitching teams in the major league this season, ranking 7th in ERA (3.83) and 10th in WHIP (1.24). Offensively, this team has the second-highest batting average in baseball at .261 while averaging 5.0 runs per game.

The Dodgers still could not figure out how to beat the Phillies after absorbing their 8th loss in 10 meetings with the NL East powerhouse. After dropping Monday’s series opener, Los Angeles (84-66) is hanging on to a two-game lead on the San Diego Padres (82-68) in an increasingly intriguing NL West title race. Powered by two big wins over the Giants in the previous series, the Dodgers have put up terrific offensive and defensive numbers in the last five games, averaging 7.4 runs per game while maintaining a 3.50 ERA. Regardless, the Dodgers’ poor head-to-head record against Philadelphia is not a good look for the defending World Series champion.