Philadelphia 76ers vs Boston Celtics Prediction & Picks - NBA

USA - NBA

Philadelphia 76ers
10/22/25 19:30
Boston Celtics

Prediction:

 

Boston Celtics to cover -2.5 spread.

-105
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 by Stephen Abiola in NBA Picks

Boston Celtics and Philadelphia 76ers will start their 2025-26 regular season campaign with a matchup at the TD Garden on Wednesday night. The Celtics will look to reclaim their Eastern Conference crown after losing it to the Cavaliers last season. They bolstered their roster during the offseason with veteran deals for Josh Minott, Chris Boucher, and Luka Garza. Bouncher is the most reliable option and will play a key role in their championship quest this season.

Philadelphia 76ers, meanwhile, had a brutal campaign last season. They had high expectations following the signing of nine-time NBA All-Star forward Paul George as a free agent. However, things didn’t work out as they had wanted, with George and Joel Embiid suffering multiple injuries. Surprisingly, they didn’t make any significant changes during the offseason, with Nick Nurse getting another chance to redeem their fortunes. He’ll pray for an injury-free campaign.

Philadelphia 76ers vs Boston Celtics Form

Table

Teams % P W L Series
3
Philadelphia 76ers
Philadelphia 76ers
1 1 1 0 1
8
Boston Celtics
Boston Celtics
0 1 0 1 -1

Philadelphia 76ers and Boston Celtics Latest Matches

Philadelphia 76ers
Philadelphia 76ers Latest matches
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 18, 2025 - NBA Summer League

Philadelphia 76ers
87 :  83
Brooklyn Nets

Jul 16, 2025 - NBA Summer League

Dallas Mavericks
82 :  90
Philadelphia 76ers

Jul 15, 2025 - NBA Summer League

Philadelphia 76ers
74 :  58
Washington Wizards

Jul 12, 2025 - NBA Summer League

Charlotte Hornets
96 :  94
Philadelphia 76ers

Jul 10, 2025 - NBA Summer League

San Antonio Spurs
111 :  70
Philadelphia 76ers

Jul 8, 2025 - NBA Summer League

Memphis Grizzlies
90 :  91
Philadelphia 76ers
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 16, 2025 - NBA Summer League

Dallas Mavericks
82 :  90
Philadelphia 76ers

Jul 12, 2025 - NBA Summer League

Charlotte Hornets
96 :  94
Philadelphia 76ers

Jul 10, 2025 - NBA Summer League

San Antonio Spurs
111 :  70
Philadelphia 76ers

Jul 8, 2025 - NBA Summer League

Memphis Grizzlies
90 :  91
Philadelphia 76ers

Jul 7, 2025 - NBA Summer League

Oklahoma City Thunder
89 :  78
Philadelphia 76ers

Apr 13, 2025 - NBA

Chicago Bulls
122 :  102
Philadelphia 76ers
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 18, 2025 - NBA Summer League

Philadelphia 76ers
87 :  83
Brooklyn Nets

Jul 15, 2025 - NBA Summer League

Philadelphia 76ers
74 :  58
Washington Wizards

Jul 5, 2025 - NBA Summer League

Philadelphia 76ers
89 :  93
Utah Jazz

Apr 9, 2025 - NBA

Philadelphia 76ers
122 :  103
Washington Wizards

Apr 7, 2025 - NBA

Philadelphia 76ers
105 :  117
Miami Heat

Apr 1, 2025 - NBA

Philadelphia 76ers
91 :  105
New York Knicks
Boston Celtics
Boston Celtics Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2025 - NBA Summer League

Atlanta Hawks
80 :  101
Boston Celtics

Jul 17, 2025 - NBA Summer League

Boston Celtics
87 :  78
Los Angeles Lakers

Jul 14, 2025 - NBA Summer League

Boston Celtics
96 :  100
Miami Heat

Jul 13, 2025 - NBA Summer League

New York Knicks
81 :  94
Boston Celtics

Jul 11, 2025 - NBA Summer League

Memphis Grizzlies
78 :  92
Boston Celtics

May 16, 2025 - NBA

Boston Celtics
81 :  119
New York Knicks
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2025 - NBA Summer League

Atlanta Hawks
80 :  101
Boston Celtics

Jul 13, 2025 - NBA Summer League

New York Knicks
81 :  94
Boston Celtics

Jul 11, 2025 - NBA Summer League

Memphis Grizzlies
78 :  92
Boston Celtics

May 14, 2025 - NBA

New York Knicks
102 :  127
Boston Celtics

May 7, 2025 - NBA

New York Knicks
91 :  90
Boston Celtics

May 5, 2025 - NBA

New York Knicks
108 :  105
Boston Celtics
W W L L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 17, 2025 - NBA Summer League

Boston Celtics
87 :  78
Los Angeles Lakers

Jul 14, 2025 - NBA Summer League

Boston Celtics
96 :  100
Miami Heat

May 16, 2025 - NBA

Boston Celtics
81 :  119
New York Knicks

May 12, 2025 - NBA

Boston Celtics
113 :  121
New York Knicks

May 10, 2025 - NBA

Boston Celtics
115 :  93
New York Knicks

Apr 27, 2025 - NBA

Boston Celtics
107 :  98
Orlando Magic

Philadelphia 76ers against Boston Celtics : Head to Head (H2H)

Philadelphia 76ers

17 %

Boston Celtics

83 %

Mar 6, 2025 - NBA

Philadelphia 76ers
105 :  123
Boston Celtics

Feb 20, 2025 - NBA

Boston Celtics
124 :  104
Philadelphia 76ers

Feb 2, 2025 - NBA

Boston Celtics
118 :  110
Philadelphia 76ers

Dec 25, 2024 - NBA

Philadelphia 76ers
118 :  114
Boston Celtics

Feb 27, 2024 - NBA

Philadelphia 76ers
99 :  117
Boston Celtics

Dec 1, 2023 - NBA

Philadelphia 76ers
119 :  125
Boston Celtics

Players list

Philadelphia 76ers
Philadelphia 76ers
J. Embiid K. Oubre Jr. T. Maxey V. Edgecombe D. Barlow
Boston Celtics
Boston Celtics
J. Brown S. Hauser N. Queta P. Pritchard D. White

Substitutes

Philadelphia 76ers
Philadelphia 76ers
J. Broome A. Bona A. Drummond K. Lowry E. Gordon Q. Grimes J. Edwards J. Walker
Boston Celtics
Boston Celtics
C. Boucher L. Garza B. Scheierman M. Shulga A. Simons H. Gonzalez X. Tillman J. Walsh J. Minott

Philadelphia 76ers - Boston Celtics Key Points

  1. Boston Celtics won their last six home games.
  2. Boston Celtics won five of their last six games.
  3. Philadelphia 76ers lost five of their last six matches.
  4. Boston Celtics are 6-4 ATS in their last 10 matches against the 76ers.

Our Philadelphia 76ers vs Boston Celtics Prediction

Boston will want to start the season strongly on Wednesday night. Historically, they have enjoyed excellent results against the 76ers, winning in four of their last five meetings. They had a strong postseason run, winning three of their four matches, including a 138-107 win over the Cavaliers. However, both teams could miss some important players. Jayson Tatum will sit out for the Celtics with a long-term Achilles injury. Jaylen brown is also doubtful with a hamstring injury. As for the 76ers, Embiid should be fit to start, although Paul George could miss out with a knee injury. They should keep it close, although we expect Boston to start the season with a win.

Our prediction for Boston Celtics vs Philadelphia 76ers: Boston Celtics to cover -2.5 spread.

Prediction:

 

Boston Celtics to cover -2.5 spread.

-105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Philadelphia 76ers vs Boston Celtics Picks