Illinois Fighting Illini vs Ohio State Buckeyes Prediction & Picks - NCAA

Prediction published on 10/11/25, 8:33 AM  by Matt Lowrimore | Modified on 10/13/25 at 9:50 PM in NCAA Picks

One of the most important games on Saturday’s Week 7 college football slate will feature a Big Ten matchup between the top-ranked Ohio State Buckeyes and the 17th-ranked Illinois Illini. Let’s take a look at the match statistics and predictions for this game between the Buckeyes and the Fighting Illini.

Ohio State enters this game with a record of 5-0 and 2-0 in the Big Ten. The Buckeyes most recently beat the Minnesota Golden Gophers in Week 6 by a score of 42-3. Ohio State’s offense had a total of 474 yards, while its defense allowed 162 yards. Quarterback Julian Sayin threw for 326 yards and three touchdowns, while running back Bo Jackson led the team in rushing with 63 yards and one touchdown.

As for Illinois, they enter this game with a record of 5-1 and 2-1 in the Big Ten. The Fighting Illini most recently beat the Purdue Boilermakers in Week 6 by a score of 43-27. The Fighting Illini offense had a total of 507 yards, while its defense allowed 453 yards. Quarterback Luke Altmyer threw for 390 yards and one touchdown, while running back Ca’Lil Valentine led the team in rushing with 95 yards and one touchdown.