Athletics vs St. Louis Cardinals Prediction & Picks - MLB

USA - MLB

Athletics
9/3/25 19:45
St. Louis Cardinals

Prediction:

 

Cardinals ML

-110
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 by Travis Pulver in MLB Picks

The Athletics will face the Cardinals in the final game of a three-game series at Busch Stadium in St. Louis, MO. First Pitch for this AL vs. NL matchup is scheduled for 7:45 p.m. EST. St. Louis took charge in the first game of the series on Monday, winning easily, 11-3. But Game Two yesterday was a tighter, more competitive, low-scoring affair that ended with the A’s coming out ahead, 2-1.

The Cardinals will turn to Matthew Liberatore to start the day on the mound. Liberatore has gone 6-11 in 25 starts with a 4.32 ERA, 1.32 WHIP, and a .269 OBA. He’s gone 4-5 in 11 starts at home with a 4.55 ERA and a .283 OBA. In his last three home starts, he failed to make it out of the fourth inning. As for the Athletics, the A’s will give Jeffrey Springs the ball to start the day. Springs has gone 10-9 in 26 starts (28 appearances)  with a 4.17 ERA, 1.19 WHIP, and a .232 OBA. He’s been at his best when on the road, where he is 5-5 with a 3.66 ERA in 14 starts (15 appearances) with a .217 OBA.

Athletics vs St. Louis Cardinals Form

Table

Teams % P W L
18
St. Louis Cardinals
St. Louis Cardinals
0.496 141 70 71
24
Athletics
Athletics
0.454 141 64 77

Athletics and St. Louis Cardinals Latest Matches

Athletics
Athletics Latest matches
W L L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 2, 2025 - MLB

Athletics
1 :  2
St. Louis Cardinals

Sep 1, 2025 - MLB

Athletics
11 :  3
St. Louis Cardinals

Aug 31, 2025 - MLB

Texas Rangers
9 :  6
Athletics

Aug 30, 2025 - MLB

Texas Rangers
9 :  3
Athletics

Aug 29, 2025 - MLB

Texas Rangers
5 :  2
Athletics

Aug 27, 2025 - MLB

Detroit Tigers
0 :  7
Athletics
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 31, 2025 - MLB

Texas Rangers
9 :  6
Athletics

Aug 30, 2025 - MLB

Texas Rangers
9 :  3
Athletics

Aug 29, 2025 - MLB

Texas Rangers
5 :  2
Athletics

Aug 27, 2025 - MLB

Detroit Tigers
0 :  7
Athletics

Aug 26, 2025 - MLB

Detroit Tigers
6 :  7
Athletics

Aug 25, 2025 - MLB

Detroit Tigers
3 :  8
Athletics
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 2, 2025 - MLB

Athletics
1 :  2
St. Louis Cardinals

Sep 1, 2025 - MLB

Athletics
11 :  3
St. Louis Cardinals

Aug 24, 2025 - MLB

Athletics
4 :  11
Seattle Mariners

Aug 23, 2025 - MLB

Athletics
2 :  1
Seattle Mariners

Aug 22, 2025 - MLB

Athletics
2 :  3
Seattle Mariners

Aug 21, 2025 - MLB

Athletics
8 :  3
Minnesota Twins
St. Louis Cardinals
St. Louis Cardinals Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 2, 2025 - MLB

Athletics
1 :  2
St. Louis Cardinals

Sep 1, 2025 - MLB

Athletics
11 :  3
St. Louis Cardinals

Aug 31, 2025 - MLB

St. Louis Cardinals
4 :  7
Cincinnati Reds

Aug 30, 2025 - MLB

St. Louis Cardinals
4 :  2
Cincinnati Reds

Aug 29, 2025 - MLB

St. Louis Cardinals
7 :  5
Cincinnati Reds

Aug 28, 2025 - MLB

Pittsburgh Pirates
1 :  4
St. Louis Cardinals
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 2, 2025 - MLB

Athletics
1 :  2
St. Louis Cardinals

Sep 1, 2025 - MLB

Athletics
11 :  3
St. Louis Cardinals

Aug 28, 2025 - MLB

Pittsburgh Pirates
1 :  4
St. Louis Cardinals

Aug 27, 2025 - MLB

Pittsburgh Pirates
2 :  1
St. Louis Cardinals

Aug 26, 2025 - MLB

Pittsburgh Pirates
8 :  3
St. Louis Cardinals

Aug 25, 2025 - MLB

Pittsburgh Pirates
6 :  7
St. Louis Cardinals
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 31, 2025 - MLB

St. Louis Cardinals
4 :  7
Cincinnati Reds

Aug 30, 2025 - MLB

St. Louis Cardinals
4 :  2
Cincinnati Reds

Aug 29, 2025 - MLB

St. Louis Cardinals
7 :  5
Cincinnati Reds

Aug 24, 2025 - MLB

St. Louis Cardinals
2 :  7
Tampa Bay Rays

Aug 22, 2025 - MLB

St. Louis Cardinals
6 :  10
Tampa Bay Rays

Aug 21, 2025 - MLB

St. Louis Cardinals
7 :  4
Tampa Bay Rays

Athletics against St. Louis Cardinals : Head to Head (H2H)

Athletics

50 %

St. Louis Cardinals

50 %

Sep 2, 2025 - MLB

Athletics
1 :  2
St. Louis Cardinals

Sep 1, 2025 - MLB

Athletics
11 :  3
St. Louis Cardinals

Apr 15, 2024 - MLB

St. Louis Cardinals
3 :  1
Athletics

Aug 14, 2023 - MLB

Athletics
5 :  7
St. Louis Cardinals

Aug 4, 2019 - MLB

St. Louis Cardinals
2 :  4
Athletics

Aug 3, 2019 - MLB

St. Louis Cardinals
3 :  8
Athletics

Athletics - St. Louis Cardinals Key Points

  1. The all-time series is currently tied at 20-20 between the A’s and Cardinals.
  2. The Cardinals have hit .222 over the last week and averaged four runs per game.
  3. The A’s have hit .243 over the last week and averaged 4.6 runs per game.
  4. Betting Public: 48% of moneyline tickets and the handle are on the Cardinals.

Our Athletics vs St. Louis Cardinals Prediction

Neither team has been impressive this season, but at the moment, I’ve got a little more faith in the Cardinals than the A’s. The A’s have been hitting the ball a little better, but the Cardinals have been decent at home (38-33) while the Athletics are 35-36 on the road. Neither pitcher will probably make it past the fifth inning, which is when the Cardinals will take control of the game. Why? Because the A’s have one of the worst pens in the league (4.80 ERA) while the Cardinals pen is solid (3.60 ERA).

Our Athletics vs. Cardinals Pick: St. Louis ML

Prediction:

 

Cardinals ML

-110
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Athletics vs St. Louis Cardinals Picks