Pittsburgh Panthers vs Notre Dame Fighting Irish Prediction & Picks - NCAA
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by Matt Lowrimore | in NCAA Picks
One of the important games on the Week 12 College Football Saturday slate will see the 9th-ranked Notre Dame Fighting Irish take on the 22nd-ranked Pittsburgh Panthers. Let's take a look at the match statistics and predictions for this game between the Fighting Irish and the Panthers.
Notre Dame enters this game with a record of 7-2, having most recently beaten the Navy Midshipmen in Week 11 by a score of 49-10. The Fighting Irish offense had a total of 502 yards, while its defense allowed 228 yards. Quarterback CJ Carr threw for 218 yards and three touchdowns, while running back Jeremiah Love led the team in rushing with 94 yards and two touchdowns.
As for Pittsburgh, they enter this game with a record of 7-2, having most recently beaten the Stanford Cardinal in Week 10 by a score of 35-20. The Panthers' offense had a total of 466 yards, while its defense allowed 326 yards. Quarterback Mason Heintschel threw for 304 yards, three touchdowns, and two interceptions, while running back Ja'Kyrian Turner led the team in rushing with 127 yards.
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Pittsburgh Panthers vs Notre Dame Fighting Irish Form
Table
Pittsburgh Panthers and Notre Dame Fighting Irish Latest Matches
5/6 (83%)
1/6 (17%)
Nov 1, 2025 - NCAA
Oct 25, 2025 - NCAA
Oct 18, 2025 - NCAA
Oct 11, 2025 - NCAA
Oct 4, 2025 - NCAA
Sep 27, 2025 - NCAA
4/5 (80%)
1/5 (20%)
Oct 25, 2025 - NCAA
Oct 4, 2025 - NCAA
Sep 27, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
3/4 (75%)
1/4 (25%)
Nov 1, 2025 - NCAA
Oct 18, 2025 - NCAA
Oct 11, 2025 - NCAA
Sep 13, 2025 - NCAA
6/6 (100%)
0/6 (0%)
Nov 8, 2025 - NCAA
Nov 1, 2025 - NCAA
Oct 18, 2025 - NCAA
Oct 11, 2025 - NCAA
Oct 4, 2025 - NCAA
Sep 27, 2025 - NCAA
5/6 (83%)
1/6 (17%)
Nov 8, 2025 - NCAA
Oct 18, 2025 - NCAA
Oct 11, 2025 - NCAA
Oct 4, 2025 - NCAA
Sep 20, 2025 - NCAA
Sep 13, 2025 - NCAA
3/4 (75%)
1/4 (25%)
Nov 1, 2025 - NCAA
Sep 27, 2025 - NCAA
Aug 31, 2025 - NCAA
Jan 9, 2025 - NCAA
Pittsburgh Panthers - Notre Dame Fighting Irish Key Points
- Notre Dame is 4-5 ATS this season
- Notre Dame is averaging 38.7 points per game this season
- Pittsburgh is 7-2 ATS this season
- Pittsburgh is averaging 39.7 points per game this season
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Our Pittsburgh Panthers vs Notre Dame Fighting Irish Prediction
The Fighting Irish continue to make their case for the College Football Playoffs and, as such, are double-digit favorites in this non-conference game against Pittsburgh. Despite winning last week against an overmatched Navy team, the Fighting Irish have still only covered the spread in four of their nine games.
Pittsburgh, on the other hand, has covered the spread in seven of their nine games. The Panthers have the advantage of playing this game at home and with an extra week of preparation. Pittsburgh is not likely to win this game, but given their success against the spread, our Notre Dame Fighting Irish vs Pittsburgh Panthers prediction is: Pittsburgh Panthers +12.5.All tips are fully researched and given in good faith, but profits cannot be guaranteed.
