New York Yankees vs Minnesota Twins Prediction & Picks - MLB

USA - MLB

New York Yankees
9/15/25 19:40
Minnesota Twins

Prediction:

 

Yankees -1.5 Runs

-115
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 by Lou Aguila in MLB Picks

The New York Yankees are 9-1 in their last 10 meetings against the Minnesota Twins. They have also covered the spread in each of these 9 wins.

This head-to-head dominance makes the Yankees the overwhelming favorites ahead of Monday’s series opener against the Twins. New York is listed at -194 moneyline on DraftKings and also valued at -115 on the -1.5 run line.

Current Form:

The Yankees have gone 3-2 in their last five games after securing two wins against their rivals, the Boston Red Sox, in their weekend series. As a result, New York has reclaimed the No.2 spot in the AL East standings with an 83-66 record and established a 1.5-game lead on the Red Sox with only a handful of game days left in the regular-season calendar. Over the last five games, the Yankees have posted a 4.91 ERA and averaged 4.7 runs per game, which is slightly lower than their season average of 5.3 runs per game.

The Twins have only won once in their last five games, causing their record to plunge to 65-84. Minnesota, now officially out of the wild-card race, has averaged a decent 4.0 runs per game on a .237 batting average in its last five games. However, the Twins have also posted a measly 6.55 ERA in this stretch.

New York Yankees vs Minnesota Twins Form

Table

Teams % P W L
7
New York Yankees
New York Yankees
0.557 149 83 66
26
Minnesota Twins
Minnesota Twins
0.436 149 65 84

New York Yankees and Minnesota Twins Latest Matches

New York Yankees
New York Yankees Latest matches
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 14, 2025 - MLB

New York Yankees
4 :  6
Boston Red Sox

Sep 13, 2025 - MLB

New York Yankees
5 :  3
Boston Red Sox

Sep 12, 2025 - MLB

New York Yankees
4 :  1
Boston Red Sox

Sep 11, 2025 - MLB

Detroit Tigers
3 :  9
New York Yankees

Sep 10, 2025 - MLB

Detroit Tigers
11 :  1
New York Yankees

Sep 9, 2025 - MLB

Detroit Tigers
12 :  2
New York Yankees
L W W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 11, 2025 - MLB

Detroit Tigers
3 :  9
New York Yankees

Sep 10, 2025 - MLB

Detroit Tigers
11 :  1
New York Yankees

Sep 9, 2025 - MLB

Detroit Tigers
12 :  2
New York Yankees

Sep 7, 2025 - MLB

Toronto Blue Jays
3 :  4
New York Yankees

Sep 6, 2025 - MLB

Toronto Blue Jays
1 :  3
New York Yankees

Sep 5, 2025 - MLB

Toronto Blue Jays
7 :  1
New York Yankees
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 14, 2025 - MLB

New York Yankees
4 :  6
Boston Red Sox

Sep 13, 2025 - MLB

New York Yankees
5 :  3
Boston Red Sox

Sep 12, 2025 - MLB

New York Yankees
4 :  1
Boston Red Sox

Sep 4, 2025 - MLB

New York Yankees
8 :  4
Houston Astros

Sep 3, 2025 - MLB

New York Yankees
7 :  8
Houston Astros

Sep 2, 2025 - MLB

New York Yankees
7 :  1
Houston Astros
Minnesota Twins
Minnesota Twins Latest matches
W L L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 14, 2025 - MLB

Arizona Diamondbacks
6 :  4
Minnesota Twins

Sep 13, 2025 - MLB

Arizona Diamondbacks
5 :  2
Minnesota Twins

Sep 12, 2025 - MLB

Arizona Diamondbacks
8 :  9
Minnesota Twins

Sep 10, 2025 - MLB

Minnesota Twins
3 :  4
Los Angeles Angels

Sep 9, 2025 - MLB

Minnesota Twins
2 :  12
Los Angeles Angels

Sep 8, 2025 - MLB

Minnesota Twins
12 :  3
Los Angeles Angels
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Sep 14, 2025 - MLB

Arizona Diamondbacks
6 :  4
Minnesota Twins

Sep 13, 2025 - MLB

Arizona Diamondbacks
5 :  2
Minnesota Twins

Sep 12, 2025 - MLB

Arizona Diamondbacks
8 :  9
Minnesota Twins

Sep 4, 2025 - MLB

Chicago White Sox
11 :  8
Minnesota Twins

Sep 3, 2025 - MLB

Chicago White Sox
4 :  3
Minnesota Twins

Sep 2, 2025 - MLB

Chicago White Sox
12 :  3
Minnesota Twins
L L W W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 10, 2025 - MLB

Minnesota Twins
3 :  4
Los Angeles Angels

Sep 9, 2025 - MLB

Minnesota Twins
2 :  12
Los Angeles Angels

Sep 8, 2025 - MLB

Minnesota Twins
12 :  3
Los Angeles Angels

Sep 7, 2025 - MLB

Minnesota Twins
5 :  1
Kansas City Royals

Sep 6, 2025 - MLB

Minnesota Twins
2 :  11
Kansas City Royals

Sep 5, 2025 - MLB

Minnesota Twins
1 :  2
Kansas City Royals

New York Yankees against Minnesota Twins : Head to Head (H2H)

New York Yankees

50 %

Minnesota Twins

50 %

Aug 13, 2025 - MLB

Minnesota Twins
4 :  1
New York Yankees

Aug 12, 2025 - MLB

Minnesota Twins
1 :  9
New York Yankees

Aug 11, 2025 - MLB

Minnesota Twins
2 :  6
New York Yankees

Mar 6, 2025 - MLB Spring Training

Minnesota Twins
8 :  4
New York Yankees

Feb 25, 2025 - MLB Spring Training

New York Yankees
4 :  5
Minnesota Twins

Jun 6, 2024 - MLB

Minnesota Twins
5 :  8
New York Yankees

New York Yankees - Minnesota Twins Key Points

  1. NY Yankees is 14-6 SU in its last 20 games.
  2. NY Yankees is 13-3 SU in its last 16 games on the road.
  3. Minnesota is 1-4 SU in its last 5 games.
  4. Minnesota is 1-6 SU in its last 7 games at home.

Our New York Yankees vs Minnesota Twins Prediction

The Yankees should be an easy pick in this one. All the metrics and trends are pointing towards a Yankees blowout win. They are 9-1 in their last 10 games against Minnesota and 14-6 SU in their last 20 games. In their last three meetings against the Twins, they have also averaged 5.33 runs per game and conceded just 2.33 runs per game.

Lefty Carlos Rodon will also start on Monday, parading a 4-1 record with a 2.43 ERA across his last five starts. Rodon has only surrendered four earned runs over 19 innings pitched against Minnesota across three starts. On the other hand, Twins RHP Simeon Woods Richardson carries a 3-2 record with a 6.75 ERA in his last five starts. He will be pitching against the Yankees for the first time in his career. The Yankees have averaged 5.3 runs per game against right-handed pitchers this season.

Our betting prediction for the New York Yankees vs. the Minnesota Twins: the Yankees -1.5 runs.

Prediction:

 

Yankees -1.5 Runs

-115
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

New York Yankees vs Minnesota Twins Picks