Minnesota Twins vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Minnesota Twins
5/1/25 13:10
Cleveland Guardians

Prediction:

 

Twins will win

-105
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 by Lou Aguila in MLB Picks

The Cleveland Guardians will try to pull off a reverse sweep in Thursday’s series finale with the Minnesota Twins at Progressive Field.

The Guardians have scored back-to-back wins over the Twins, thanks to another strong performance from their pitching staff. Cleveland, who is pitching a 4.40 ERA this season, has allowed only three runs in the last two games. Luis Ortiz blanked the Twins in 6.1 innings while closer Emmanuel Clase earned another save after fending off a comeback attempt from Minnesota.

The two consecutive losses have dropped the Twins’ record to five games below .500 at 13-18. Pitching 3.54 ERA, Minnesota has done a solid job on the mound in this series, though their previously explosive offense went silent with only three runs scored between Games 2 and 3.

Minnesota Twins vs Cleveland Guardians Form

Table

Teams % P W L
8
Cleveland Guardians
Cleveland Guardians
0.581 31 18 13
25
Minnesota Twins
Minnesota Twins
0.406 32 13 19

Minnesota Twins and Cleveland Guardians Latest Matches

Minnesota Twins
Minnesota Twins Latest matches
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 30, 2025 - MLB

Minnesota Twins
2 :  4
Cleveland Guardians

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Los Angeles Angels
0 :  5
Minnesota Twins

Apr 26, 2025 - MLB

Los Angeles Angels
1 :  5
Minnesota Twins

Apr 25, 2025 - MLB

Los Angeles Angels
4 :  11
Minnesota Twins
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 27, 2025 - MLB

Los Angeles Angels
0 :  5
Minnesota Twins

Apr 26, 2025 - MLB

Los Angeles Angels
1 :  5
Minnesota Twins

Apr 25, 2025 - MLB

Los Angeles Angels
4 :  11
Minnesota Twins

Apr 24, 2025 - MLB

Chicago White Sox
3 :  0
Minnesota Twins

Apr 23, 2025 - MLB

Chicago White Sox
3 :  6
Minnesota Twins

Apr 22, 2025 - MLB

Chicago White Sox
2 :  4
Minnesota Twins
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 30, 2025 - MLB

Minnesota Twins
2 :  4
Cleveland Guardians

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 20, 2025 - MLB

Minnesota Twins
2 :  6
Atlanta Braves

Apr 19, 2025 - MLB

Minnesota Twins
3 :  4
Atlanta Braves

Apr 18, 2025 - MLB

Minnesota Twins
4 :  6
Atlanta Braves
Cleveland Guardians
Cleveland Guardians Latest matches
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 30, 2025 - MLB

Minnesota Twins
2 :  4
Cleveland Guardians

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Boston Red Sox
13 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
7 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 30, 2025 - MLB

Minnesota Twins
2 :  4
Cleveland Guardians

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Boston Red Sox
13 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
7 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 20, 2025 - MLB

Cleveland Guardians
5 :  4
Pittsburgh Pirates

Apr 19, 2025 - MLB

Cleveland Guardians
3 :  0
Pittsburgh Pirates

Apr 18, 2025 - MLB

Cleveland Guardians
10 :  7
Pittsburgh Pirates

Apr 17, 2025 - MLB

Cleveland Guardians
2 :  6
Baltimore Orioles

Apr 16, 2025 - MLB

Cleveland Guardians
1 :  9
Baltimore Orioles

Apr 15, 2025 - MLB

Cleveland Guardians
6 :  3
Baltimore Orioles

Minnesota Twins against Cleveland Guardians : Head to Head (H2H)

Minnesota Twins

33 %

Cleveland Guardians

67 %

Apr 30, 2025 - MLB

Minnesota Twins
2 :  4
Cleveland Guardians

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Sep 19, 2024 - MLB

Minnesota Twins
2 :  3
Cleveland Guardians

Sep 18, 2024 - MLB

Minnesota Twins
4 :  5
Cleveland Guardians

Sep 17, 2024 - MLB

Minnesota Twins
4 :  1
Cleveland Guardians

Minnesota Twins - Cleveland Guardians Key Points

  1. Minnesota is 6-3 SU in its last 9 games.
  2. Minnesota is 2-9 SU in its last 11 games when playing on the road against Cleveland.
  3. Cleveland is 8-4 SU in its last 12 games.
  4. Cleveland is 10-5 SU in its last 15 games at home.

Our Minnesota Twins vs Cleveland Guardians Prediction

Minnesota will be counting on RHP Simeon Woods Richardson to power them to a victory in game 4. Woods Richardson (4.71 ERA) will be matched up against Guardians starter Ben Lively (4.21 ERA), who has had shutout and four-run stints in his last five starts. The Guardians' bullpen has done a pretty good job in the previous two games, but I expect the Twins' batters to perform much better in Game 4 after getting 3-game worth of scouting reports on the Guardians' pitchers. Our betting prediction for the Minnesota Twins vs. the Cleveland Guardians: The Twins will win.

Prediction:

 

Twins will win

-105
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Minnesota Twins vs Cleveland Guardians Picks