Minnesota Twins vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Minnesota Twins
4/30/25 18:10
Cleveland Guardians

Prediction:

 

Twins -1.5 Runs

+140
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 by Lou Aguila in MLB Picks

The Cleveland Guardians and the Minnesota Twins are heading into Wednesday’s Game 3 at Progressive Field with the series tied after splitting the first two games.

The Twins’ four-game winning streak ended on Tuesday as Chris Paddack and company stifled Minnesota batters. Minnesota sits in fourth place in the American League Central with a 13-17 record, batting .233 with 118 runs and pitching 3.51 in the season.

The Guardians earned their first win in four matches behind an exceptional mound performance from their pitching staff. Chris Paddack allowed one earned run in 5.0 inning while Emmanuel Clase bagged his fourth save of the season after securing the last three outs in the 9th inning. Cleveland is second in the AL Central with 16-13 record, 1.5 games behind the 18-12 Detroit Tigers.

Minnesota Twins vs Cleveland Guardians Form

Table

Teams % P W L
9
Cleveland Guardians
Cleveland Guardians
0.552 29 16 13
22
Minnesota Twins
Minnesota Twins
0.433 30 13 17

Minnesota Twins and Cleveland Guardians Latest Matches

Minnesota Twins
Minnesota Twins Latest matches
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Los Angeles Angels
0 :  5
Minnesota Twins

Apr 26, 2025 - MLB

Los Angeles Angels
1 :  5
Minnesota Twins

Apr 25, 2025 - MLB

Los Angeles Angels
4 :  11
Minnesota Twins

Apr 24, 2025 - MLB

Chicago White Sox
3 :  0
Minnesota Twins
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 27, 2025 - MLB

Los Angeles Angels
0 :  5
Minnesota Twins

Apr 26, 2025 - MLB

Los Angeles Angels
1 :  5
Minnesota Twins

Apr 25, 2025 - MLB

Los Angeles Angels
4 :  11
Minnesota Twins

Apr 24, 2025 - MLB

Chicago White Sox
3 :  0
Minnesota Twins

Apr 23, 2025 - MLB

Chicago White Sox
3 :  6
Minnesota Twins

Apr 22, 2025 - MLB

Chicago White Sox
2 :  4
Minnesota Twins
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 20, 2025 - MLB

Minnesota Twins
2 :  6
Atlanta Braves

Apr 19, 2025 - MLB

Minnesota Twins
3 :  4
Atlanta Braves

Apr 18, 2025 - MLB

Minnesota Twins
4 :  6
Atlanta Braves

Apr 10, 2025 - MLB

Minnesota Twins
2 :  3
Kansas City Royals
Cleveland Guardians
Cleveland Guardians Latest matches
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Boston Red Sox
13 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
7 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians

Apr 23, 2025 - MLB

New York Yankees
5 :  1
Cleveland Guardians
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Boston Red Sox
13 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
7 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians

Apr 23, 2025 - MLB

New York Yankees
5 :  1
Cleveland Guardians
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 20, 2025 - MLB

Cleveland Guardians
5 :  4
Pittsburgh Pirates

Apr 19, 2025 - MLB

Cleveland Guardians
3 :  0
Pittsburgh Pirates

Apr 18, 2025 - MLB

Cleveland Guardians
10 :  7
Pittsburgh Pirates

Apr 17, 2025 - MLB

Cleveland Guardians
2 :  6
Baltimore Orioles

Apr 16, 2025 - MLB

Cleveland Guardians
1 :  9
Baltimore Orioles

Apr 15, 2025 - MLB

Cleveland Guardians
6 :  3
Baltimore Orioles

Minnesota Twins against Cleveland Guardians : Head to Head (H2H)

Minnesota Twins

33 %

Cleveland Guardians

67 %

Apr 29, 2025 - MLB

Minnesota Twins
1 :  2
Cleveland Guardians

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Sep 19, 2024 - MLB

Minnesota Twins
2 :  3
Cleveland Guardians

Sep 18, 2024 - MLB

Minnesota Twins
4 :  5
Cleveland Guardians

Sep 17, 2024 - MLB

Minnesota Twins
4 :  1
Cleveland Guardians

Sep 16, 2024 - MLB

Minnesota Twins
3 :  4
Cleveland Guardians

Minnesota Twins - Cleveland Guardians Key Points

  1. Minnesota is 4-1 SU in its last 5 games.
  2. Minnesota is 4-12 SU in its last 16 games against Cleveland.
  3. Cleveland is 2-4 SU in its last 6 games.
  4. Cleveland is 8-2 SU in its last 10 games when playing at home against Minnesota.

Our Minnesota Twins vs Cleveland Guardians Prediction

Fearless Forecast: Minnesota Twins strike back to take Game 3 by at least two runs.

I picked the Twins to win and cover -1.5 runs against the Guardians in Game 3 with the expectation of a solid outing from Pablo Lopez (2.30 ERA), who is posting a 2.00 ERA over his last three starts vs. the Guardians. I like Lopez’s chance of winning his duel with the Guardians’ projected starter, Luiz Lopez (5.96 ERA), mainly because Lopez has been unpredictable on the mound this season. For the second straight start, Lopez collected 8 strikeouts but threw away four earned runs in 4.1 innings in a 1-5 loss to the Yankees on April 23. Meanwhile, Minnesota holds a 4-1 SU record in its last 5 games and a 3-1 slate against the spread in its previous four games. Our betting prediction for the Minnesota Twins vs. the Cleveland Guardians: Twins -1.5 Runs

Prediction:

 

Twins -1.5 Runs

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Minnesota Twins vs Cleveland Guardians Picks