Minnesota Twins vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Minnesota Twins
4/28/25 18:10
Cleveland Guardians

Prediction:

 

Minnesota Twins wins the match

+102
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 by Carlos Zabala in MLB Picks

The Twins secured their first sweep of the year, beating the Angels at Target Field in all three games. The final game was even better, as their star pitcher completely dominated the Angels. Ryan pitched seven scoreless innings, striking out 11, allowing only four hits, and throwing just one BB.

This will be the first time the Guardians and Twins meet in 2025. They shared dominance in the Central Division in recent years until the recent push that saw the Tigers and Royals join the ranks. Although the Guardians come in with a better record, they didn't have a good weekend against the Red Sox, losing the series to Boston in a 3-13 rout. The pitching suffered an unusual collapse in the fifth inning, allowing five earned runs.

Nolan Jones hit a 3-run homer, which proved to be of little use in an already wide-open game due to a poor outing by Allen and poor defense.

While this was happening, the Twins won the final game of the series 5-0 against the Angels; Correa had his first big offensive afternoon with the Twins in the 2025 season, going 3-for-4.

Minnesota Twins vs Cleveland Guardians Form

Table

Teams % P W L
10
Cleveland Guardians
Cleveland Guardians
0.543 162 88 74
27
Minnesota Twins
Minnesota Twins
0.432 162 70 92

Minnesota Twins and Cleveland Guardians Latest Matches

Minnesota Twins
Minnesota Twins Latest matches
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 27, 2025 - MLB

Los Angeles Angels
0 :  5
Minnesota Twins

Apr 26, 2025 - MLB

Los Angeles Angels
1 :  5
Minnesota Twins

Apr 25, 2025 - MLB

Los Angeles Angels
4 :  11
Minnesota Twins

Apr 24, 2025 - MLB

Chicago White Sox
3 :  0
Minnesota Twins

Apr 23, 2025 - MLB

Chicago White Sox
3 :  6
Minnesota Twins

Apr 22, 2025 - MLB

Chicago White Sox
2 :  4
Minnesota Twins
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 27, 2025 - MLB

Los Angeles Angels
0 :  5
Minnesota Twins

Apr 26, 2025 - MLB

Los Angeles Angels
1 :  5
Minnesota Twins

Apr 25, 2025 - MLB

Los Angeles Angels
4 :  11
Minnesota Twins

Apr 24, 2025 - MLB

Chicago White Sox
3 :  0
Minnesota Twins

Apr 23, 2025 - MLB

Chicago White Sox
3 :  6
Minnesota Twins

Apr 22, 2025 - MLB

Chicago White Sox
2 :  4
Minnesota Twins
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 20, 2025 - MLB

Minnesota Twins
2 :  6
Atlanta Braves

Apr 19, 2025 - MLB

Minnesota Twins
3 :  4
Atlanta Braves

Apr 18, 2025 - MLB

Minnesota Twins
4 :  6
Atlanta Braves

Apr 10, 2025 - MLB

Minnesota Twins
2 :  3
Kansas City Royals

Apr 9, 2025 - MLB

Minnesota Twins
4 :  0
Kansas City Royals

Apr 8, 2025 - MLB

Minnesota Twins
1 :  2
Kansas City Royals
Cleveland Guardians
Cleveland Guardians Latest matches
W W L L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 27, 2025 - MLB

Boston Red Sox
13 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
7 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians

Apr 23, 2025 - MLB

New York Yankees
5 :  1
Cleveland Guardians

Apr 22, 2025 - MLB

New York Yankees
2 :  3
Cleveland Guardians

Apr 21, 2025 - MLB

New York Yankees
4 :  6
Cleveland Guardians
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 27, 2025 - MLB

Boston Red Sox
13 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
7 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians

Apr 23, 2025 - MLB

New York Yankees
5 :  1
Cleveland Guardians

Apr 22, 2025 - MLB

New York Yankees
2 :  3
Cleveland Guardians

Apr 21, 2025 - MLB

New York Yankees
4 :  6
Cleveland Guardians
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 20, 2025 - MLB

Cleveland Guardians
5 :  4
Pittsburgh Pirates

Apr 19, 2025 - MLB

Cleveland Guardians
3 :  0
Pittsburgh Pirates

Apr 18, 2025 - MLB

Cleveland Guardians
10 :  7
Pittsburgh Pirates

Apr 17, 2025 - MLB

Cleveland Guardians
2 :  6
Baltimore Orioles

Apr 16, 2025 - MLB

Cleveland Guardians
1 :  9
Baltimore Orioles

Apr 15, 2025 - MLB

Cleveland Guardians
6 :  3
Baltimore Orioles

Minnesota Twins against Cleveland Guardians : Head to Head (H2H)

Minnesota Twins

33 %

Cleveland Guardians

67 %

Sep 19, 2024 - MLB

Minnesota Twins
2 :  3
Cleveland Guardians

Sep 17, 2024 - MLB

Minnesota Twins
4 :  1
Cleveland Guardians

Sep 16, 2024 - MLB

Minnesota Twins
3 :  4
Cleveland Guardians

Aug 11, 2024 - MLB

Cleveland Guardians
5 :  3
Minnesota Twins

Aug 9, 2024 - MLB

Cleveland Guardians
3 :  6
Minnesota Twins

May 19, 2024 - MLB

Minnesota Twins
2 :  5
Cleveland Guardians

Minnesota Twins - Cleveland Guardians Key Points

  1. Twins are the third team in MLB with the fewest home runs, hitting 21 this season
  2. The Guardians have struck out 215 times in 876 at-bats this season
  3. Only three of the last 10 Guardians-Twins games have resulted in a Game Total of OVER
  4. The Guardians' pitching WHIP is 1.39, the sixth-worst in MLB

Our Minnesota Twins vs Cleveland Guardians Prediction

The Guardians' 15-12 record is a good start to the season for the Guardians, but it's starting to worry that their bullpen is far from the dominant version it was in the 2024 season. In 2024, the Guards' bullpen led the MLB in ERA, posting a 2.57 ERA, and the Brewers' bullpen was the second-best, posting a 3.11 ERA. In 2025, things have changed for the worse, dropping out of the top six in this category with a 3.42 ERA. Ober will be the starting pitcher for the Twins, and he struck out 12 the last time he faced the Guardians. Our prediction for Guardians vs Twins is: Twins ML.

Prediction:

 

Minnesota Twins wins the match

+102
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Minnesota Twins vs Cleveland Guardians Picks