Minnesota Timberwolves vs Portland Trail Blazers Prediction & Picks - NBA

USA - NBA

Minnesota Timberwolves
10/22/25 22:00
Portland Trail Blazers

Prediction:

 

Less than 221.5 goals

-120
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 by Erik Gibbs | in NBA Picks

As they prepare to take on the Minnesota Timberwolves tonight, the Portland Trail Blazers enter the new season in a period of transition and uncertainty. Their identity as a playoff contender has been tested in recent years, and the ongoing question surrounding Damian Lillard's future continues to cast a shadow over their direction. Assuming Lillard remains on the roster, he remains the undisputed centerpiece of Portland's offense — a proven scorer and leader capable of changing a game with a single hot stretch.

The Blazers' late-season and preseason performances have highlighted both their promise and their shortcomings. Offensively, they can score in bursts, especially when their shooters find rhythm from deep. Their spacing and transition play have looked fluid at times, but extended cold spells have exposed a lack of structure when Lillard sits. Defensively, Portland remains a work in progress.

Their interior coverage is inconsistent, and opponents have repeatedly punished them with second-chance opportunities and efficient scoring in the paint. Without significant improvement in rotations and rebounding, those weaknesses may persist through the early part of the season.

The Minnesota Timberwolves, by contrast, enter the matchup with clear direction and growing confidence. Over the past two seasons, they've built an identity rooted in defense and effort, anchored by Rudy Gobert's rim protection and Anthony Edwards's emergence as a legitimate offensive star. Minnesota's recent form reflects a team that has matured collectively — their ball movement has improved, their defensive communication is sharp, and their rebounding strength gives them a consistent edge.

Minnesota Timberwolves vs Portland Trail Blazers Form

Table

Teams % P W L Series
5
Minnesota Timberwolves
Minnesota Timberwolves
0.655 29 19 10 2
10
Portland Trail Blazers
Portland Trail Blazers
0.414 29 12 17 -1

Minnesota Timberwolves and Portland Trail Blazers Latest Matches

Minnesota Timberwolves
Minnesota Timberwolves Latest matches
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 19, 2025 - NBA Summer League

Houston Rockets
104 :  101
Minnesota Timberwolves

Jul 16, 2025 - NBA Summer League

Phoenix Suns
85 :  89
Minnesota Timberwolves

Jul 15, 2025 - NBA Summer League

Minnesota Timberwolves
89 :  73
Detroit Pistons

Jul 12, 2025 - NBA Summer League

Minnesota Timberwolves
94 :  83
Denver Nuggets

Jul 10, 2025 - NBA Summer League

New Orleans Pelicans
91 :  98
Minnesota Timberwolves

May 28, 2025 - NBA

Minnesota Timberwolves
94 :  124
Oklahoma City Thunder
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 19, 2025 - NBA Summer League

Houston Rockets
104 :  101
Minnesota Timberwolves

Jul 16, 2025 - NBA Summer League

Phoenix Suns
85 :  89
Minnesota Timberwolves

Jul 10, 2025 - NBA Summer League

New Orleans Pelicans
91 :  98
Minnesota Timberwolves

May 26, 2025 - NBA

Oklahoma City Thunder
128 :  126
Minnesota Timberwolves

May 24, 2025 - NBA

Oklahoma City Thunder
101 :  143
Minnesota Timberwolves

May 14, 2025 - NBA

Golden State Warriors
110 :  121
Minnesota Timberwolves
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 15, 2025 - NBA Summer League

Minnesota Timberwolves
89 :  73
Detroit Pistons

Jul 12, 2025 - NBA Summer League

Minnesota Timberwolves
94 :  83
Denver Nuggets

May 28, 2025 - NBA

Minnesota Timberwolves
94 :  124
Oklahoma City Thunder

May 22, 2025 - NBA

Minnesota Timberwolves
103 :  118
Oklahoma City Thunder

May 20, 2025 - NBA

Minnesota Timberwolves
88 :  114
Oklahoma City Thunder

May 12, 2025 - NBA

Minnesota Timberwolves
117 :  110
Golden State Warriors
Portland Trail Blazers
Portland Trail Blazers Latest matches
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 19, 2025 - NBA Summer League

Portland Trail Blazers
87 :  111
Phoenix Suns

Jul 17, 2025 - NBA Summer League

Houston Rockets
83 :  102
Portland Trail Blazers

Jul 15, 2025 - NBA Summer League

Portland Trail Blazers
93 :  87
New Orleans Pelicans

Jul 12, 2025 - NBA Summer League

Memphis Grizzlies
96 :  86
Portland Trail Blazers

Jul 11, 2025 - NBA Summer League

Portland Trail Blazers
106 :  73
Golden State Warriors

Apr 13, 2025 - NBA

Los Angeles Lakers
81 :  109
Portland Trail Blazers
L W L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 17, 2025 - NBA Summer League

Houston Rockets
83 :  102
Portland Trail Blazers

Jul 12, 2025 - NBA Summer League

Memphis Grizzlies
96 :  86
Portland Trail Blazers

Apr 13, 2025 - NBA

Los Angeles Lakers
81 :  109
Portland Trail Blazers

Apr 11, 2025 - NBA

Golden State Warriors
103 :  86
Portland Trail Blazers

Apr 6, 2025 - NBA

San Antonio Spurs
109 :  120
Portland Trail Blazers

Mar 25, 2025 - NBA

Cleveland Cavaliers
122 :  111
Portland Trail Blazers
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 19, 2025 - NBA Summer League

Portland Trail Blazers
87 :  111
Phoenix Suns

Jul 15, 2025 - NBA Summer League

Portland Trail Blazers
93 :  87
New Orleans Pelicans

Jul 11, 2025 - NBA Summer League

Portland Trail Blazers
106 :  73
Golden State Warriors

Apr 9, 2025 - NBA

Portland Trail Blazers
126 :  133
Utah Jazz

Apr 4, 2025 - NBA

Portland Trail Blazers
113 :  118
Chicago Bulls

Apr 3, 2025 - NBA

Portland Trail Blazers
112 :  103
Toronto Raptors

Minnesota Timberwolves against Portland Trail Blazers : Head to Head (H2H)

Minnesota Timberwolves

67 %

Portland Trail Blazers

33 %

Feb 8, 2025 - NBA

Portland Trail Blazers
98 :  114
Minnesota Timberwolves

Nov 13, 2024 - NBA

Minnesota Timberwolves
98 :  106
Portland Trail Blazers

Nov 12, 2024 - NBA

Minnesota Timberwolves
108 :  122
Portland Trail Blazers

Nov 8, 2024 - NBA

Portland Trail Blazers
102 :  127
Minnesota Timberwolves

Mar 4, 2024 - NBA

Portland Trail Blazers
114 :  119
Minnesota Timberwolves

Feb 15, 2024 - NBA

Minnesota Timberwolves
128 :  91
Portland Trail Blazers

Players list

Minnesota Timberwolves
Minnesota Timberwolves
R. Gobert J. Randle A. Edwards D. DiVincenzo J. McDaniels
Portland Trail Blazers
Portland Trail Blazers
D. Clingan S. Sharpe J. Holiday D. Avdija T. Camara

Substitutes

Minnesota Timberwolves
Minnesota Timberwolves
N. Reid J. Beringer B. Hyland M. Conley T. Shannon Jr. J. Clark R. Dillingham J. Juzang L. Miller J. Ingles
Portland Trail Blazers
Portland Trail Blazers
Y. Hansen M. Thybulle R. Rupert R. Williams III D. Reath D. Lillard B. Wesley S. Henderson J. Grant K. Murray

Minnesota Timberwolves - Portland Trail Blazers Key Points

  1. The Trail Blazers are 4-1 in their last 5 games as home underdogs vs. Northwest Division teams
  2. The Timberwolves are 11-1 in their last 12 games as road favorites vs. Western Conference teams
  3. The Timberwolves are 1-5 ATS in their last 6 season openers vs. Western Conference teams
  4. The Over is 0-5 in the Timberwolves’ last 5 road openers

Our Minnesota Timberwolves vs Portland Trail Blazers Prediction

For Portland, success depends almost entirely on Lillard's production. He remains capable of explosive scoring nights, with range and clutch ability few players can match. Henderson's development will be key, as his speed could help push tempo and relieve some of the offensive burden. However, consistency on both ends remains elusive for the young roster.

Minnesota's balance is what separates them. Karl-Anthony Towns provides another scoring outlet, stretching the floor with his shooting and complementing Gobert's inside dominance. Their supporting cast, including Jaden McDaniels and Mike Conley, adds poise and discipline.

Unless Lillard delivers a vintage, high-efficiency performance, Portland may struggle to keep pace. The Timberwolves' defense, rebounding edge, and depth make them strong favorites to control the game's tempo. Expect Minnesota to pull away late, earning a 115–102 victory built on superior balance and defensive consistency. Our prediction for Portland Trail Blazers vs Minnesota Timberwolves: Under 221.5 points.

Prediction:

 

Less than 221.5 goals

-120
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Minnesota Timberwolves vs Portland Trail Blazers Picks