San Diego Padres vs Milwaukee Brewers Prediction & Picks - MLB

USA - MLB

San Diego Padres
10/6/26 21:30
Milwaukee Brewers

Prediction:

 

San Diego to win

-135
$250 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Bill Christy in MLB Picks

The San Diego Padres are hoping a change of scenery will help them tonight. They are down 2-0 in their NLDS series with the Milwaukee Brewers, and a loss tonight could put them in a hole they can't climb out.

In game one, Jacob Misiorowski was not as dominant as many expected him to be. He only pitched 4 innings and allowed 2 runs on 4 hits while striking out 6. However, he left the game tied 2-2, and his bullpen helped piece together the win. William Contreras homered to break the tie in the 7th, and Trevor Megill came in to close things out in the 9th with 2 strikeouts.

In the 2nd game, Michael King of the Padres went 5 strong innings and allowed just 1 run on 3 hits. However, he was matched by Logan Henderson of the Brewers, who went 5 innings and allowed 1 earned run as well. Once again, with the game tied late in the contest, a Brewer came up in a big way. This time, it was Jackson Chourio who hit an RBI single that walked it off for the Brewers.

Tonight, Dustin May of the Brewers will get his 1st postseason start since 2019. He will be opposed by Nick Pivetta, who is coming off a decent start against the Cubs in their last series.

San Diego Padres vs Milwaukee Brewers Form

San Diego Padres and Milwaukee Brewers Latest Matches

San Diego Padres
San Diego Padres Latest matches
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Oct 4, 2026 - MLB

Milwaukee Brewers
4 :  3
San Diego Padres

Oct 3, 2026 - MLB

Milwaukee Brewers
3 :  2
San Diego Padres

Sep 30, 2026 - MLB

San Diego Padres
4 :  1
Chicago Cubs

Sep 29, 2026 - MLB

San Diego Padres
8 :  0
Chicago Cubs

Sep 27, 2026 - MLB

San Diego Padres
9 :  4
Arizona Diamondbacks

Sep 26, 2026 - MLB

San Diego Padres
10 :  7
Arizona Diamondbacks
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 30, 2026 - MLB

San Diego Padres
4 :  1
Chicago Cubs

Sep 29, 2026 - MLB

San Diego Padres
8 :  0
Chicago Cubs

Sep 27, 2026 - MLB

San Diego Padres
9 :  4
Arizona Diamondbacks

Sep 26, 2026 - MLB

San Diego Padres
10 :  7
Arizona Diamondbacks

Sep 25, 2026 - MLB

San Diego Padres
4 :  11
Arizona Diamondbacks

Sep 20, 2026 - MLB

San Diego Padres
7 :  3
Miami Marlins
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Oct 4, 2026 - MLB

Milwaukee Brewers
4 :  3
San Diego Padres

Oct 3, 2026 - MLB

Milwaukee Brewers
3 :  2
San Diego Padres

Sep 24, 2026 - MLB

Los Angeles Dodgers
2 :  4
San Diego Padres

Sep 23, 2026 - MLB

Los Angeles Dodgers
1 :  5
San Diego Padres

Sep 22, 2026 - MLB

Los Angeles Dodgers
7 :  0
San Diego Padres

Sep 17, 2026 - MLB

Colorado Rockies
2 :  9
San Diego Padres
Milwaukee Brewers
Milwaukee Brewers Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Oct 4, 2026 - MLB

Milwaukee Brewers
4 :  3
San Diego Padres

Oct 3, 2026 - MLB

Milwaukee Brewers
3 :  2
San Diego Padres

Sep 27, 2026 - MLB

Milwaukee Brewers
6 :  4
St. Louis Cardinals

Sep 26, 2026 - MLB

Milwaukee Brewers
3 :  2
St. Louis Cardinals

Sep 25, 2026 - MLB

Milwaukee Brewers
8 :  4
St. Louis Cardinals

Sep 24, 2026 - MLB

Philadelphia Phillies
1 :  5
Milwaukee Brewers
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Oct 4, 2026 - MLB

Milwaukee Brewers
4 :  3
San Diego Padres

Oct 3, 2026 - MLB

Milwaukee Brewers
3 :  2
San Diego Padres

Sep 27, 2026 - MLB

Milwaukee Brewers
6 :  4
St. Louis Cardinals

Sep 26, 2026 - MLB

Milwaukee Brewers
3 :  2
St. Louis Cardinals

Sep 25, 2026 - MLB

Milwaukee Brewers
8 :  4
St. Louis Cardinals

Sep 13, 2026 - MLB

Milwaukee Brewers
3 :  4
Cincinnati Reds
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 24, 2026 - MLB

Philadelphia Phillies
1 :  5
Milwaukee Brewers

Sep 23, 2026 - MLB

Philadelphia Phillies
1 :  4
Milwaukee Brewers

Sep 22, 2026 - MLB

Philadelphia Phillies
6 :  4
Milwaukee Brewers

Sep 20, 2026 - MLB

Baltimore Orioles
0 :  3
Milwaukee Brewers

Sep 19, 2026 - MLB

Baltimore Orioles
0 :  1
Milwaukee Brewers

Sep 18, 2026 - MLB

Baltimore Orioles
5 :  6
Milwaukee Brewers

San Diego Padres against Milwaukee Brewers : Head to Head (H2H)

San Diego Padres

50 %

Milwaukee Brewers

50 %

Oct 4, 2026 - MLB

Milwaukee Brewers
4 :  3
San Diego Padres

Oct 3, 2026 - MLB

Milwaukee Brewers
3 :  2
San Diego Padres

Aug 12, 2026 - MLB

San Diego Padres
4 :  3
Milwaukee Brewers

Aug 11, 2026 - MLB

San Diego Padres
11 :  2
Milwaukee Brewers

Aug 10, 2026 - MLB

San Diego Padres
3 :  2
Milwaukee Brewers

May 14, 2026 - MLB

Milwaukee Brewers
7 :  1
San Diego Padres
San Diego Padres vs Milwaukee Brewers Picks

San Diego Padres - Milwaukee Brewers Key Points

  1. Padres are 6-0 in Pivetta’s last 6 starts as a favorite.
  2. Padres are 6-1 in their last 7 games vs. a team with a winning % above .600.
  3. Padres are 5-0 in Pivetta’s last 5 home starts.
  4. Dustin May has not pitched in the postseason in over 5 years.

Our San Diego Padres vs Milwaukee Brewers Prediction

The Padres were the hottest team heading into the postseason in the National League. They blew through the Chicago Cubs but have had trouble here on the road against these Brewers. However, we believe that Pivetta’s postseason experience will help them in a must-win game tonight at home. That, combined with May’s limited postseason experience, should be a good thing for these Padres.

Our prediction for San Diego Padres vs Milwaukee Brewers: San Dieg to win

Prediction:

 

San Diego to win

-135
$250 offered for betting!

Welcome Bonus for the San Diego Padres vs Milwaukee Brewers match!

FanDuel Bonus Bets

FanDuel is offering some great promos for the beginning of football season, including their welcome offer of $250, which can be activated for this San Diego Padres vs Milwaukee Brewers match! Simply sign up and place a first bet of at least $5. You can do this during your first 5 days with FanDuel, earning a total of $250 in bet reset tokens!

Remember, the offer is only open to new sign-ups!

$250 in bonus bets for San Diego Padres vs Milwaukee Brewers!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.