Milwaukee Brewers vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

Milwaukee Brewers
8/20/25 20:05
Chicago Cubs

Prediction:

 

OVER 6.5

-124
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 by Travis Pulver in MLB Picks

The Milwaukee Brewers will take on the Cubs tonight at Wrigley Field in Chicago. Fans can follow the action once the game gets underway at 8:05 p.m. EST.

After seeing their 14-game winning streak come to an end in Cincinnati, Milwaukee fans were probably hoping that the 7-0 win over the Cubs on Monday was the start of another streak. But with a pair of losses on Tuesday, the Brewers are starting to streak in the wrong direction. Jacob Misiorowski is scheduled to start for the Brewers tonight. The youngster is 4-1 this season in eight starts with a 3.89 ERA, 1.13 WHIP, and a .180 OBA. While he has been great at home, he’s had some issues on the road. He’s gone 1-1 in four starts with a 7.36 ERA and .236 OBA. In his last road start, he only lasted 1 1/3 innings vs. the Reds in Cincinnati, giving up four hits, three walks, and five earned runs while striking out three. As for the Cubs, Colin Rea will get the start. Rea has gone 9-5 with a save in 21 starts (25 appearances), he has a 3.99 ERA, and a .265 OBA.  He has gone 4-3 at home in 13 starts (14 appearances) with a 4.13 ERA and .258 OBA.

Milwaukee Brewers vs Chicago Cubs Form

Table

Teams % P W L
1
Milwaukee Brewers
Milwaukee Brewers
0.627 126 79 47
5
Chicago Cubs
Chicago Cubs
0.571 126 72 54

Milwaukee Brewers and Chicago Cubs Latest Matches

Milwaukee Brewers
Milwaukee Brewers Latest matches
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs

Aug 17, 2025 - MLB

Milwaukee Brewers
2 :  3
Cincinnati Reds

Aug 16, 2025 - MLB

Milwaukee Brewers
6 :  5
Cincinnati Reds

Aug 15, 2025 - MLB

Milwaukee Brewers
10 :  8
Cincinnati Reds
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Aug 13, 2025 - MLB

Pittsburgh Pirates
5 :  12
Milwaukee Brewers

Aug 12, 2025 - MLB

Pittsburgh Pirates
0 :  14
Milwaukee Brewers

Aug 11, 2025 - MLB

Pittsburgh Pirates
1 :  7
Milwaukee Brewers

Aug 10, 2025 - MLB

New York Mets
6 :  7
Milwaukee Brewers

Aug 9, 2025 - MLB

New York Mets
4 :  7
Milwaukee Brewers

Aug 8, 2025 - MLB

New York Mets
2 :  3
Milwaukee Brewers
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs

Aug 17, 2025 - MLB

Milwaukee Brewers
2 :  3
Cincinnati Reds

Aug 16, 2025 - MLB

Milwaukee Brewers
6 :  5
Cincinnati Reds

Aug 15, 2025 - MLB

Milwaukee Brewers
10 :  8
Cincinnati Reds
Chicago Cubs
Chicago Cubs Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs

Aug 17, 2025 - MLB

Pittsburgh Pirates
3 :  4
Chicago Cubs

Aug 16, 2025 - MLB

Pittsburgh Pirates
1 :  3
Chicago Cubs

Aug 15, 2025 - MLB

Pittsburgh Pirates
3 :  2
Chicago Cubs
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs

Aug 17, 2025 - MLB

Pittsburgh Pirates
3 :  4
Chicago Cubs

Aug 16, 2025 - MLB

Pittsburgh Pirates
1 :  3
Chicago Cubs

Aug 15, 2025 - MLB

Pittsburgh Pirates
3 :  2
Chicago Cubs
W L L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 14, 2025 - MLB

Chicago Cubs
1 :  2
Toronto Blue Jays

Aug 13, 2025 - MLB

Chicago Cubs
4 :  1
Toronto Blue Jays

Aug 12, 2025 - MLB

Chicago Cubs
1 :  5
Toronto Blue Jays

Aug 10, 2025 - MLB

Chicago Cubs
2 :  3
St. Louis Cardinals

Aug 9, 2025 - MLB

Chicago Cubs
9 :  1
St. Louis Cardinals

Aug 8, 2025 - MLB

Chicago Cubs
0 :  5
St. Louis Cardinals

Milwaukee Brewers against Chicago Cubs : Head to Head (H2H)

Milwaukee Brewers

50 %

Chicago Cubs

50 %

Aug 19, 2025 - MLB

Milwaukee Brewers
1 :  4
Chicago Cubs

Aug 19, 2025 - MLB

Milwaukee Brewers
4 :  6
Chicago Cubs

Aug 18, 2025 - MLB

Milwaukee Brewers
7 :  0
Chicago Cubs

Jul 30, 2025 - MLB

Chicago Cubs
10 :  3
Milwaukee Brewers

Jul 29, 2025 - MLB

Chicago Cubs
3 :  9
Milwaukee Brewers

Jul 28, 2025 - MLB

Chicago Cubs
4 :  8
Milwaukee Brewers

Milwaukee Brewers - Chicago Cubs Key Points

  1. In two of his last three road starts, Misiorowski has given up five earned runs before the fourth inning.
  2. In three of his last five home starts, Rea gave up only a single run; he gave up two and five in the other two.
  3. Milwaukee is 27-19 following a loss this season.
  4. Chicago is 34-37 after a win this season.

Our Milwaukee Brewers vs Chicago Cubs Prediction

Based on Misiorowski’s track record in road games, I’d have to lean towards the Cubs to win this one. However, I am not confident that the Chicago ML is the best bet. Rea is pitching well, but got hit hard by the Brewers in Milwaukee (July 29) to the tune of nine hits and four earned runs in four innings. Misiorowski pitched vs. the Cubs on July 28, giving up three runs (two earned). With the TOTAL set at just 6.5 runs, jump on the OVER before it goes up.

Our Brewers vs. Cubs Prediction: OVER 6.5

Prediction:

 

OVER 6.5

-124
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Milwaukee Brewers vs Chicago Cubs Picks