Buffalo Bills vs Miami Dolphins Prediction & Picks - NFL

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Buffalo Bills
9/18/25 20:15
Miami Dolphins

Prediction:

 

UNDER 49.5

-110
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 by Travis Pulver | in NFL Picks

The Miami Dolphins will head to upstate New York for Thursday Night Football and a date with the Buffalo Bills. Kickoff for this AFC East division battle will kickoff at 8:15 p.m. EST at Highmark Stadium in Orchard Park, NY. The game will be broadcast/streamed on Prime Video.

Buffalo is off to a strong start this season after recording an amazing come-from-behind win over Baltimore. The game wasn’t nearly as thrilling in Week Two, but the Bills still did what mattered most vs. the Jets—they won. As for Miami, it has been a different story. The Dolphins couldn’t do anything right against the Colts in Week 12, losing 33-8. Although Tua Tagovailoa threw for over 300 passing yards in Week 2 against the Patriots, the team still lost. The Bills were gashed by the Ravens' passing game in Week 1, but the Jets were unable to exploit any gaps in coverage. However, if Tua can get the passing game on track, he has some talented playmakers who could make this game more challenging than expected.

Both teams have several players listed as questionable on the injury report, but no one is expected to miss.


 

Buffalo Bills vs Miami Dolphins Form

Table

Teams Pts P W L
8 Buffalo Bills
0.706 17 12 5
22 Miami Dolphins
0.412 17 7 10

Buffalo Bills and Miami Dolphins Latest Matches

Buffalo Bills
Buffalo Bills Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 14, 2025 - NFL

New York Jets
10 :  30
Buffalo Bills

Sep 7, 2025 - NFL

Buffalo Bills
41 :  40
Baltimore Ravens

Jan 26, 2025 - NFL

Kansas City Chiefs
32 :  29
Buffalo Bills

Jan 19, 2025 - NFL

Buffalo Bills
27 :  25
Baltimore Ravens

Jan 12, 2025 - NFL

Buffalo Bills
31 :  7
Denver Broncos

Jan 5, 2025 - NFL

New England Patriots
23 :  16
Buffalo Bills
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Sep 7, 2025 - NFL

Buffalo Bills
41 :  40
Baltimore Ravens

Jan 19, 2025 - NFL

Buffalo Bills
27 :  25
Baltimore Ravens

Jan 12, 2025 - NFL

Buffalo Bills
31 :  7
Denver Broncos

Dec 29, 2024 - NFL

Buffalo Bills
40 :  14
New York Jets

Dec 22, 2024 - NFL

Buffalo Bills
24 :  21
New England Patriots

Dec 1, 2024 - NFL

Buffalo Bills
35 :  10
San Francisco 49ers
W L W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 14, 2025 - NFL

New York Jets
10 :  30
Buffalo Bills

Jan 26, 2025 - NFL

Kansas City Chiefs
32 :  29
Buffalo Bills

Jan 5, 2025 - NFL

New England Patriots
23 :  16
Buffalo Bills

Dec 15, 2024 - NFL

Detroit Lions
42 :  48
Buffalo Bills

Dec 8, 2024 - NFL

Los Angeles Rams
44 :  42
Buffalo Bills

Nov 10, 2024 - NFL

Indianapolis Colts
20 :  30
Buffalo Bills
Miami Dolphins
Miami Dolphins Latest matches
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 14, 2025 - NFL

Miami Dolphins
27 :  33
New England Patriots

Sep 7, 2025 - NFL

Indianapolis Colts
33 :  8
Miami Dolphins

Jan 5, 2025 - NFL

New York Jets
32 :  20
Miami Dolphins

Dec 29, 2024 - NFL

Cleveland Browns
3 :  20
Miami Dolphins

Dec 22, 2024 - NFL

Miami Dolphins
29 :  17
San Francisco 49ers

Dec 15, 2024 - NFL

Houston Texans
20 :  12
Miami Dolphins
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 14, 2025 - NFL

Miami Dolphins
27 :  33
New England Patriots

Dec 22, 2024 - NFL

Miami Dolphins
29 :  17
San Francisco 49ers

Dec 8, 2024 - NFL

Miami Dolphins
32 :  26
New York Jets

Nov 24, 2024 - NFL

Miami Dolphins
34 :  15
New England Patriots

Nov 17, 2024 - NFL

Miami Dolphins
34 :  19
Las Vegas Raiders

Oct 27, 2024 - NFL

Miami Dolphins
27 :  28
Arizona Cardinals
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 7, 2025 - NFL

Indianapolis Colts
33 :  8
Miami Dolphins

Jan 5, 2025 - NFL

New York Jets
32 :  20
Miami Dolphins

Dec 29, 2024 - NFL

Cleveland Browns
3 :  20
Miami Dolphins

Dec 15, 2024 - NFL

Houston Texans
20 :  12
Miami Dolphins

Nov 28, 2024 - NFL

Green Bay Packers
30 :  17
Miami Dolphins

Nov 11, 2024 - NFL

Los Angeles Rams
15 :  23
Miami Dolphins

Buffalo Bills against Miami Dolphins : Head to Head (H2H)

Buffalo Bills

100 %

Miami Dolphins

0 %

Nov 3, 2024 - NFL

Buffalo Bills
30 :  27
Miami Dolphins

Sep 12, 2024 - NFL

Miami Dolphins
10 :  31
Buffalo Bills

Jan 7, 2024 - NFL

Miami Dolphins
14 :  21
Buffalo Bills

Oct 1, 2023 - NFL

Buffalo Bills
48 :  20
Miami Dolphins

Jan 15, 2023 - NFL

Buffalo Bills
34 :  31
Miami Dolphins

Buffalo Bills - Miami Dolphins Key Points

  1. Miami leads the all-time series vs. 62-60-1.
  2. Buffalo has won six in a row and 13 of the last 14 vs. the Dolphins.
  3. The Bills have not lost to the Dolphins at home since 2016.
  4. Betting Public: In early betting, 98% of moneyline tickets are on the Bills, but only 59% of spread tickets.

Our Buffalo Bills vs Miami Dolphins Prediction

Buffalo will win this game, or at least they should. Josh Allen is already in midseason form, and the run game is getting there, too. Miami, on the other hand, doesn’t look too good. They look like a team that doesn’t have a prayer of covering a 12.5-point spread. However, the Bills are 2-9 ATS in their last 11 games where they were double-digit favorites. Four of the last six games between these two were decided by one score. The Bills will probably crush the Dolphins, but the spread is too big. However, I don’t see Miami scoring much, if at all, which will help keep the score relatively low.

Our Buffalo vs. Miami Pick: UNDER 49.5

Prediction:

 

UNDER 49.5

-110
10X100 in FanCash offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Buffalo Bills vs Miami Dolphins Picks