Ole Miss Rebels vs LSU Tigers Prediction & Picks - NCAA
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by Matt Lowrimore | in NCAA Picks
One of the best games on the Saturday Week 5 college football slate will see the 4th-ranked LSU Tigers take on the 13th-ranked Ole Miss Rebels in an SEC matchup. Let’s take a look at the match statistics and predictions for this game between the Tigers and the Rebels.
LSU enters this game with a record 4-0 and 1-0 in the SEC. The Tigers most recently beat the SE Louisiana Lions in Week 4 by a score of 56-10. LSU’s offense had a total of 530 yards, while its defense allowed 205 yards. Quarterback Garrett Nussmeier threw for 273 yards and three touchdowns, while running back Ju’Juan Johnson led the team in rushing with 43 yards and two touchdowns.
As for Ole Miss, they enter this game with a record of 4-0 and 2-0 in the SEC. The Rebels most recently beat the Tulane Green Wave in Week 4 by a score of 45-10. Ole Miss’ offense had a total of 548 yards, while its defense allowed 282 yards. Quarterback Trinidad Chambliss threw for 307 yards and two touchdowns, while also leading the team in rushing with 112 yards.
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Ole Miss Rebels vs LSU Tigers Form
Table
Ole Miss Rebels and LSU Tigers Latest Matches
4/5 (80%)
1/5 (20%)
Sep 20, 2025 - NCAA
Sep 13, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
Sep 28, 2024 - NCAA
3/4 (75%)
1/4 (25%)
Sep 20, 2025 - NCAA
Sep 13, 2025 - NCAA
Aug 30, 2025 - NCAA
Sep 28, 2024 - NCAA
1/1 (100%)
0/1 (0%)
Sep 6, 2025 - NCAA
6/6 (100%)
0/6 (0%)
Sep 20, 2025 - NCAA
Sep 13, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
Sep 21, 2024 - NCAA
Sep 14, 2024 - NCAA
4/4 (100%)
0/4 (0%)
Sep 20, 2025 - NCAA
Sep 13, 2025 - NCAA
Sep 6, 2025 - NCAA
Sep 21, 2024 - NCAA
2/3 (67%)
1/3 (33%)
Aug 30, 2025 - NCAA
Sep 14, 2024 - NCAA
Sep 1, 2024 - NCAA
Ole Miss Rebels - LSU Tigers Key Points
- LSU is 2-2 ATS this season
- LSU is averaging 35.0 points per game this season
- Ole Miss is 3-1 ATS this season
- Ole Miss is averaging 44.8 points per game this season
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Our Ole Miss Rebels vs LSU Tigers Prediction
LSU has some good wins this season, but this will likely be their biggest test as they head into Oxford to take on the Rebels. The one criticism about LSU is that they have not put their opponents away, not counting the game against an inferior SE Louisiana team. The Tigers won by just seven against Clemson, 16 against Louisiana Tech, and 10 against Florida.
In the same sense, Ole Miss has had some close games too, but the Rebels look to be more balanced offensively. Further, Ole Miss has two quarterbacks who can beat you in multiple ways, which is why they are averaging more than 40 points per game. Regardless of whether Austin Simmons or Trinidad Chambliss starts at quarterback, the home crowd could be the difference for Ole Miss. That and the balance they employ on offense means our LSU Tigers vs Ole Miss Rebels prediction is: Ole Miss Rebels ML.All tips are fully researched and given in good faith, but profits cannot be guaranteed.
