Houston Cougars vs LSU Tigers Prediction & Picks - NCAA Division I, FBS, Playoffs

USA - NCAA Division I, FBS, Playoffs

Houston Cougars
12/27/25 21:15
LSU Tigers

Prediction:

 

Houston Cougars ML

-135
$200 offered for betting!

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 by Matt Lowrimore | in Football Picks

The final game on the Saturday College Football slate will see the LSU Tigers take on the 21st-ranked Houston Cougars in the Kinder’s Texas Bowl. Let’s take a look at the match statistics and predictions for this game between the Tigers and the Cougars.

LSU enters this game having finished 7-5 this season. The Tigers most recently lost to the Oklahoma Sooners in Week 14 by a score of 17-13. LSU’s offense had a total of 198 yards, while its defense allowed 393 yards. Quarterback Michael Van Buren Jr. threw for 96 yards, one touchdown, and one interception, while running back Caden Durham led the team in rushing with 46 yards.

As for Houston, they enter this game having finished 9-3 this season. The Cougars most recently beat the Baylor Bears in Week 14 by a score of 31-24. Houston’s offense had a total of 417 yards, while its defense allowed 421 yards. Quarterback Connor Weigman threw for 201 yards, one touchdown, and one interception, while also leading the team in rushing with 121 yards and two touchdowns.

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Houston Cougars vs LSU Tigers Form

Table

Teams Pts P W L
31 Houston Cougars
1 1 1 0
99 LSU Tigers
0 1 0 1

Houston Cougars and LSU Tigers Latest Matches

Houston Cougars
Houston Cougars Latest matches
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 29, 2025 - NCAA

Baylor Bears
24 :  31
Houston Cougars

Nov 22, 2025 - NCAA

Houston Cougars
14 :  17
TCU Horned Frogs

Nov 7, 2025 - NCAA

UCF Knights
27 :  30
Houston Cougars

Nov 1, 2025 - NCAA

Houston Cougars
35 :  45
West Virginia Mountaineers

Oct 25, 2025 - NCAA

Arizona State Sun Devils
16 :  24
Houston Cougars

Oct 18, 2025 - NCAA

Houston Cougars
31 :  28
Arizona Wildcats
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 22, 2025 - NCAA

Houston Cougars
14 :  17
TCU Horned Frogs

Nov 1, 2025 - NCAA

Houston Cougars
35 :  45
West Virginia Mountaineers

Oct 18, 2025 - NCAA

Houston Cougars
31 :  28
Arizona Wildcats

Oct 4, 2025 - NCAA

Houston Cougars
11 :  35
Texas Tech Red Raiders

Sep 12, 2025 - NCAA

Houston Cougars
36 :  20
Colorado Buffaloes

Aug 28, 2025 - NCAA

Houston Cougars
27 :  0
Stephen F. Austin Lumberjacks
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Nov 29, 2025 - NCAA

Baylor Bears
24 :  31
Houston Cougars

Nov 7, 2025 - NCAA

UCF Knights
27 :  30
Houston Cougars

Oct 25, 2025 - NCAA

Arizona State Sun Devils
16 :  24
Houston Cougars

Oct 11, 2025 - NCAA

Oklahoma State Cowboys
17 :  39
Houston Cougars

Sep 26, 2025 - NCAA

Oregon State Beavers
24 :  27
Houston Cougars

Sep 6, 2025 - NCAA

Rice Owls
9 :  35
Houston Cougars
LSU Tigers
LSU Tigers Latest matches
L L L W W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 29, 2025 - NCAA

Oklahoma Sooners
17 :  13
LSU Tigers

Nov 22, 2025 - NCAA

LSU Tigers
13 :  10
Western Kentucky Hilltoppers

Nov 15, 2025 - NCAA

LSU Tigers
23 :  22
Arkansas Razorbacks

Nov 8, 2025 - NCAA

Alabama Crimson Tide
20 :  9
LSU Tigers

Oct 25, 2025 - NCAA

LSU Tigers
25 :  49
Texas AM Aggies

Oct 18, 2025 - NCAA

Vanderbilt Commodores
31 :  24
LSU Tigers
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Nov 22, 2025 - NCAA

LSU Tigers
13 :  10
Western Kentucky Hilltoppers

Nov 15, 2025 - NCAA

LSU Tigers
23 :  22
Arkansas Razorbacks

Oct 25, 2025 - NCAA

LSU Tigers
25 :  49
Texas AM Aggies

Oct 11, 2025 - NCAA

LSU Tigers
20 :  10
South Carolina Gamecocks

Sep 20, 2025 - NCAA

LSU Tigers
56 :  10
Southeastern Louisiana Lions

Sep 13, 2025 - NCAA

LSU Tigers
20 :  10
Florida Gators
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 29, 2025 - NCAA

Oklahoma Sooners
17 :  13
LSU Tigers

Nov 8, 2025 - NCAA

Alabama Crimson Tide
20 :  9
LSU Tigers

Oct 18, 2025 - NCAA

Vanderbilt Commodores
31 :  24
LSU Tigers

Sep 27, 2025 - NCAA

Ole Miss Rebels
24 :  19
LSU Tigers

Aug 30, 2025 - NCAA

Clemson Tigers
10 :  17
LSU Tigers

Sep 14, 2024 - NCAA

South Carolina Gamecocks
33 :  36
LSU Tigers

Houston Cougars - LSU Tigers Key Points

  1. LSU is averaging 22.0 points per game
  2. LSU is allowing an average of 18.3 points per game
  3. Houston is averaging 28.3 points per game
  4. Houston is allowing an average of 21.8 points per game
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Our Houston Cougars vs LSU Tigers Prediction

Houston is the small favorite in this matchup, but still looks to be the betting option. The Cougars have consistently been solid all season, while LSU has clearly had a down season. The Tigers fired their head coach midway through the season, and after that point, the Tigers appeared to check out.

LSU did hire Lane Kiffin to help turn their program around, so there is some incentive to play well in this game, as he is sure to be watching. Regardless, the Cougars have been much more effective offensively, while also having a solid defense. 

LSU, on the other hand, has not been consistent offensively; therefore, our LSU Tigers vs Houston Cougars prediction is: Houston Cougars ML.

Prediction:

 

Houston Cougars ML

-135
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Houston Cougars vs LSU Tigers Picks