Miami Hurricanes vs Louisville Cardinals Prediction & Picks - NCAA
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by Matt Lowrimore | in NCAA Picks
Friday night will feature a handful of interesting games, including an ACC matchup between the 2nd-ranked Miami Hurricanes and the Louisville Cardinals. Let’s take a look at the match statistics and predictions for this game between the Hurricanes and the Cardinals.
Louisville enters this game with a record of 4-1 and 1-1 in the ACC. The Cardinals most recently lost to the Virginia Cavaliers by a score of 30-27 in Week 6. Louisville’s offense had a total of 383 yards, while its defense allowed 237 yards. Quarterback Miller Moss threw for 329 yards, two touchdowns, and one interception, while running back Isaac Brown led the team in rushing with 66 yards.
As for Miami, they enter this game with a record of 5-0 and 1-0 in the ACC. The Hurricanes most recently beat the Florida State Seminoles in Week 6 by a score of 28-22. Miami’s offense had a total of 338 yards, while its defense allowed 404 yards. Quarterback Carson Beck threw for 241 yards and four touchdowns, while running back Mark Fletcher Jr. led the team in rushing with 40 yards.
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Miami Hurricanes vs Louisville Cardinals Form
Table
Miami Hurricanes and Louisville Cardinals Latest Matches
6/6 (100%)
0/6 (0%)
Oct 4, 2025 - NCAA
Sep 20, 2025 - NCAA
Sep 13, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 31, 2025 - NCAA
Sep 21, 2024 - NCAA
5/5 (100%)
0/5 (0%)
Sep 20, 2025 - NCAA
Sep 13, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 31, 2025 - NCAA
Sep 14, 2024 - NCAA
3/3 (100%)
0/3 (0%)
Oct 4, 2025 - NCAA
Sep 21, 2024 - NCAA
Aug 31, 2024 - NCAA
4/6 (67%)
2/6 (33%)
Oct 4, 2025 - NCAA
Sep 27, 2025 - NCAA
Sep 20, 2025 - NCAA
Sep 5, 2025 - NCAA
Aug 30, 2025 - NCAA
Sep 28, 2024 - NCAA
3/4 (75%)
1/4 (25%)
Oct 4, 2025 - NCAA
Sep 20, 2025 - NCAA
Sep 5, 2025 - NCAA
Aug 30, 2025 - NCAA
1/2 (50%)
1/2 (50%)
Sep 27, 2025 - NCAA
Sep 28, 2024 - NCAA
Miami Hurricanes - Louisville Cardinals Key Points
- Miami is 1-0 ATS vs the ACC
- Miami is averaging 28.0 points per game vs the ACC
- Louisville is 1-1 ATS vs the ACC
- Louisville is averaging 30.5 points per game vs the ACC
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Our Miami Hurricanes vs Louisville Cardinals Prediction
Miami is the clear favorite, and even though they are playing at home, the spread in this game looks to be too steep. The Hurricanes have no doubt been one of the best teams in the country; however, they have not always dominated their opponents. In three games against a Power 5 opponent (Notre Dame, Florida, and Florida State), the Hurricanes have won by an average margin of 9.3 points per game.
Louisville, on the other hand, is coming off a tough upset loss at home against Virginia in overtime, but has otherwise been solid on both sides of the ball. Given that Miami has been vulnerable to slow starts or late comeback attempts, our Louisville Cardinals vs Miami Hurricanes prediction is: Louisville Cardinals +14.5 Alternate Spread.All tips are fully researched and given in good faith, but profits cannot be guaranteed.
