Los Angeles Dodgers vs Arizona Diamondbacks Prediction & Picks - MLB

Prediction published on 9/23/25, 6:21 PM  by Lou Aguila in MLB Picks

The Los Angeles Dodgers will visit the Arizona Diamondbacks in a highly crucial series starting Monday at Chase Field.

The Dodgers are -166 road favorites ahead of their series opener against the D-Backs, who took 2 of 3 games in their most recent series late August.

Current Form:

The Dodgers emerged from the weekend as the No.1 team in the NL West after winning 3 of 4 games in their previous series with the San Francisco Giants. At 88-68, Los Angeles currently holds a 2.0-game lead over the San Diego Padres with barely a week left in the regular season. The Diamondbacks scored two crucial wins over the Philadelphia Phillies to stay in the postseason hunt. Arizona is only one game off a wild-card spot, trailing the Cincinnati Reds and the New York Mets, who carry identical records of 80-76.

Stats Over The Last 5 Games:

In their last five games, the Dodgers have flexed their might on the mound and at the plate, boasting a 2.40 ERA while averaging a decent 4.6 runs per game. Arizona has pumped up similar numbers on offense in its last five games, averaging 4.5 runs per game on a .279 BA. However, the D-Backs bullpen has given up a 7.80 ERA in the stretch.

Pitchers Matchup:

Dodgers RHP 1-1, 3.29 ERA Shohei Ohtani vs. Diamondbacks Brandon Pfaadt (13-8, 5.02 ERA).