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by Lou Aguila in MLB Picks
The St. Louis Cardinals and the Kansas City Royals take the field again on Thursday for Game 2 of their series at Busch Stadium.
Inconsistent pitching keeps hurting the Cardinals this season. That was evident on Wednesday asthe Cardinals allowed 10 runs in a 7-10 loss to the Royals in their series-opener. This came after allowing 8 and 11 runs in 2 of their previous 3-game series against the Rangers. Over the last five games, the Cards have surrendered over 6.28 ERA and 1.56 WHIP.
The Royals are 32-29 this season, third in the American League Central. Over the last five games, Kansas City has pitched a 3.40 ERA and batted 2.3 runs on a .256 batting average. If they want to beat the Cardinals again and improve their place in the standings, their batting numbers have to jump up because 3 runs a game won’t cut it in today’s league even with an elite pitching number.
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Kansas City Royals vs St. Louis Cardinals Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
9
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0.548 | 62 | 34 | 28 |
17
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0.524 | 63 | 33 | 30 |
Kansas City Royals and St. Louis Cardinals Latest Matches

3/6 (50%)
3/6 (50%)
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2/6 (33%)
4/6 (67%)
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3/6 (50%)
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3/6 (50%)
3/6 (50%)
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3/6 (50%)
3/6 (50%)
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3/6 (50%)
3/6 (50%)
Jun 1, 2025 - MLB
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Kansas City Royals against St. Louis Cardinals : Head to Head (H2H)
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Kansas City Royals - St. Louis Cardinals Key Points
- The Royals and the Cardinals are 5-5 in their last 10 games
- The Royals are pitching a 3.40 ERA over their last five games
- The Cardinals are pitching a 6.28 ERA over their last five games
- The Cardinals are 6-4 in their last 10 games
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Our Kansas City Royals vs St. Louis Cardinals Prediction
Why you should bet on the Over 8.5 to win (Win $100 on a $100 Bet): The Royals and the Cardinals average 11.0 runs per game over their last 10 meetings. Thursday night’s pitchers, Cole Ragans of the Royals and Matthew Liberatore, are coming off bad starts. Ragans allowed 4 runs in each of his last two starts, while Liberatore let up 5 runs in a 1-11 loss to the Rangers. Remember, the Cardinals are pitching a 6.00+ ERA over their last five games, which means there’s a strong chance we will see another high-scoring duel between these two teams. By the way, the total has gone OVER in 6 of their 8 last meetings, including Tuesday’s 10-7 win by the Royals.
Our betting prediction for the Kansas City Royals vs. St. Louis Cardinals: Over 8.5 Runs
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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