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by Carlos Zabala in MLB Picks
Both the Royals and Guardians are currently out of the playoffs; Cleveland is three games away from the last Wild Card spot, and Kansas City is 3.5, so the Royals-Guardians series at Progressive Field is vital to both teams' hopes.
Game 1 of this four-game series was won by the Guards 10-2, with Cecconi no-hitting them into the eighth inning against the Royals. The Royals' offense continued to stall in Game 2, with Joey Cantillo shutting them out for eight innings. The Royals were then able to snap their three-game losing streak by winning the game 3-4-3, turning the score around with timely hits from Loftin and an RBI double from Maikel García.
Betting action for Game 4 has Cleveland as a -140 favorite at the bookmakers; This year they have been able to justify their home-field favoritism by playing at Progressive Field, as they have a 25-18 record in those games.
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Kansas City Royals vs Cleveland Guardians Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
14
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0.51 | 145 | 74 | 71 |
15
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0.507 | 146 | 74 | 72 |
Kansas City Royals and Cleveland Guardians Latest Matches

3/6 (50%)
3/6 (50%)
Sep 10, 2025 - MLB
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3/6 (50%)
3/6 (50%)
Sep 7, 2025 - MLB
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3/6 (50%)
3/6 (50%)
Sep 10, 2025 - MLB
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5/6 (83%)
1/6 (17%)
Sep 10, 2025 - MLB
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Sep 5, 2025 - MLB
4/6 (67%)
2/6 (33%)
Sep 10, 2025 - MLB
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Aug 31, 2025 - MLB
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Aug 29, 2025 - MLB
4/6 (67%)
2/6 (33%)
Sep 7, 2025 - MLB
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Sep 4, 2025 - MLB
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Sep 2, 2025 - MLB
Kansas City Royals against Cleveland Guardians : Head to Head (H2H)
50 %
50 %
Sep 10, 2025 - MLB
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Kansas City Royals - Cleveland Guardians Key Points
- The Guards and Royals are among the top five MLB teams for fewest runs per game
- 34-37 is the Royals' road record this year; 37-34 is the Red Sox's
- 24-14 is the Guardians' record this year against division rivals
- 46-47 is the Royals' record playing at night this season
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Our Kansas City Royals vs Cleveland Guardians Prediction
On Thursday, two pitchers who have navigated innings deep into their recent starts will collide. Pitching for the Guardians will be Gavin Williams, who pitched seven complete innings in his last two starts against the Mariners and Rays, in two games Cleveland won.
Kolek, who has never faced the Guards lineup in his career, will pitch for the Royals. He had a very efficient last outing, throwing 95 pitches.
The betting record shows that both teams are making more Game Total Under than Over; the Royals, in particular, have a 61-84 O/U betting record in 2025.
Our prediction for Royals vs Guardians is: Under 7.5 runs.
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