Kansas City Royals vs Cleveland Guardians Prediction & Picks - MLB

Prediction published on 9/10/25, 3:40 PM  by Lou Aguila in MLB Picks

The Cleveland Guardians will attempt to push their winning streak to six games in Wednesday’s series finale against the Kansas City Royals at Progressive Field.

The streaking Guardians are listed at -110 moneyline at DraftKings, while the Royals offer a +151 value if they cover the 1.5-run handicap or beat Cleveland by two runs.

Current Form:

The Guardians have won their last five games, including the first two games of this final regular-season series with the Royals, improving their record to 74-70 – second in the AL Central and 2.5 games behind the Seattle Mariners, who sit third in the AL wild card race.

The Royals have lost their last three games, which puts them in danger of falling to .500 with a 73-72 record. Kansas City is still in contention for the final three wild-card spot in the American League, trailing the Mariners by four games.

Offense in the last 5 games:

Powered by a 10-run explosion in Game 1 against Kansas City, the Guardians have upped their average run per game in their last five games to 5.0 runs per game while batting .282 at the plate. The Royals have only scored three runs in their last four games, causing their run production over the last five games to drop to 3.3 runs per game.

Pitching & Projected Starters:

The Guardians, who have posted a jaw-dropping 1.09 ERA over the last five games, will start left-handed pitcher Logan Allen. Allen is 7-11 with a 4.46 ERA in the season, but his ERA over his last five starts has increased to 6.66 after giving up 17 earned runs over the last 24 innings across three starts.

The Royals will give relief pitcher Jonathan Bowlan an opportunity to start on Wednesday. Bowlan has gone 1-2 with a 3.57 ERA in the season. In his last appearance on Tuesday, Bowlan came off the bullpen and struck out three batters in one inning.