Kansas City Royals vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Kansas City Royals
9/9/25 18:40
Cleveland Guardians

Prediction:

 

The Guardians will win

-121
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 by Lou Aguila in MLB Picks

Winners in their last four games, the Cleveland Guardians will march into Tuesday’s Game 2 against the Kansas City Royals determined to extend their hot streak to five games.

DraftKings has listed the Guardians as -121 favorites to win again over the Royals.

Current Form:

The Guardians have won their last four games, including Monday’s 10-2 win over the Royals. Sporting a 3.90 ERA in the season, Cleveland has further lowered their ERA over the last five games to 1.84 after surrendering only six runs during the four-game win streak. Cleveland has also experienced a slight improvement in their offense, averaging 4.9 runs per game over the said 5-game span. At 73-70, Cleveland is still out of the AL wildcard picture, trailing the Seattle Mariners – the current holder of the final wild card slot – by 2.5 games.

The Royals suffered back-to-back losses to Minnesota 1-5 and Cleveland 2-10 after winning three games in a row over the weekend. As a result, Kansas City slid to third in the AL Central with a 73-71 record, trailing Cleveland by only a half game and the Mariners by three games in the wild card race. The Royals’ ERA in their last five games has increased to 4.30 after surrendering 10 runs to Cleveland in Game 1. Kansas City has averaged 4.3 runs per game in the said five-game stretch, though they have just scored a total of three runs in the past two games.

Kansas City Royals vs Cleveland Guardians Form

Table

Teams % P W L
14
Cleveland Guardians
Cleveland Guardians
0.51 143 73 70
15
Kansas City Royals
Kansas City Royals
0.507 144 73 71

Kansas City Royals and Cleveland Guardians Latest Matches

Kansas City Royals
Kansas City Royals Latest matches
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 8, 2025 - MLB

Kansas City Royals
2 :  10
Cleveland Guardians

Sep 7, 2025 - MLB

Minnesota Twins
5 :  1
Kansas City Royals

Sep 6, 2025 - MLB

Minnesota Twins
2 :  11
Kansas City Royals

Sep 5, 2025 - MLB

Minnesota Twins
1 :  2
Kansas City Royals

Sep 4, 2025 - MLB

Los Angeles Angels
3 :  4
Kansas City Royals

Sep 3, 2025 - MLB

Los Angeles Angels
4 :  3
Kansas City Royals
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 7, 2025 - MLB

Minnesota Twins
5 :  1
Kansas City Royals

Sep 6, 2025 - MLB

Minnesota Twins
2 :  11
Kansas City Royals

Sep 5, 2025 - MLB

Minnesota Twins
1 :  2
Kansas City Royals

Sep 4, 2025 - MLB

Los Angeles Angels
3 :  4
Kansas City Royals

Sep 3, 2025 - MLB

Los Angeles Angels
4 :  3
Kansas City Royals

Sep 2, 2025 - MLB

Los Angeles Angels
5 :  1
Kansas City Royals
L W L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 8, 2025 - MLB

Kansas City Royals
2 :  10
Cleveland Guardians

Aug 27, 2025 - MLB

Kansas City Royals
12 :  1
Chicago White Sox

Aug 26, 2025 - MLB

Kansas City Royals
5 :  4
Chicago White Sox

Aug 25, 2025 - MLB

Kansas City Royals
0 :  7
Chicago White Sox

Aug 24, 2025 - MLB

Kansas City Royals
10 :  8
Detroit Tigers

Aug 23, 2025 - MLB

Kansas City Royals
2 :  4
Detroit Tigers
Cleveland Guardians
Cleveland Guardians Latest matches
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 8, 2025 - MLB

Kansas City Royals
2 :  10
Cleveland Guardians

Sep 7, 2025 - MLB

Cleveland Guardians
2 :  1
Tampa Bay Rays

Sep 6, 2025 - MLB

Cleveland Guardians
3 :  2
Tampa Bay Rays

Sep 5, 2025 - MLB

Cleveland Guardians
7 :  1
Tampa Bay Rays

Sep 4, 2025 - MLB

Cleveland Guardians
2 :  4
Tampa Bay Rays

Sep 3, 2025 - MLB

Cleveland Guardians
8 :  1
Boston Red Sox
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 8, 2025 - MLB

Kansas City Royals
2 :  10
Cleveland Guardians

Aug 31, 2025 - MLB

Seattle Mariners
4 :  2
Cleveland Guardians

Aug 30, 2025 - MLB

Seattle Mariners
3 :  4
Cleveland Guardians

Aug 29, 2025 - MLB

Seattle Mariners
4 :  5
Cleveland Guardians

Aug 27, 2025 - MLB

Tampa Bay Rays
3 :  4
Cleveland Guardians

Aug 26, 2025 - MLB

Tampa Bay Rays
0 :  3
Cleveland Guardians
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 7, 2025 - MLB

Cleveland Guardians
2 :  1
Tampa Bay Rays

Sep 6, 2025 - MLB

Cleveland Guardians
3 :  2
Tampa Bay Rays

Sep 5, 2025 - MLB

Cleveland Guardians
7 :  1
Tampa Bay Rays

Sep 4, 2025 - MLB

Cleveland Guardians
2 :  4
Tampa Bay Rays

Sep 3, 2025 - MLB

Cleveland Guardians
8 :  1
Boston Red Sox

Sep 2, 2025 - MLB

Cleveland Guardians
7 :  11
Boston Red Sox

Kansas City Royals against Cleveland Guardians : Head to Head (H2H)

Kansas City Royals

50 %

Cleveland Guardians

50 %

Sep 8, 2025 - MLB

Kansas City Royals
2 :  10
Cleveland Guardians

Jul 27, 2025 - MLB

Cleveland Guardians
1 :  4
Kansas City Royals

Jul 26, 2025 - MLB

Cleveland Guardians
6 :  4
Kansas City Royals

Jul 26, 2025 - MLB

Cleveland Guardians
3 :  5
Kansas City Royals

Apr 13, 2025 - MLB

Kansas City Royals
4 :  2
Cleveland Guardians

Apr 12, 2025 - MLB

Kansas City Royals
3 :  6
Cleveland Guardians

Kansas City Royals - Cleveland Guardians Key Points

  1. Kansas City is 7-13 SU in its last 20 games played in September.
  2. Kansas City is 6-3 SU in its last 9 games played on a Tuesday.
  3. Cleveland is 5-1 SU in its last 6 games.
  4. Cleveland is 4-1 SU in its last 5 games at home.

Our Kansas City Royals vs Cleveland Guardians Prediction

The Guardians are my pick to win over the Royals. Cleveland is 5-1 SU in its last 6 games and 4-1 SU in its last 5 games at home. Starter Joey Cantillo has posted a sturdy 3.42 ERA across his last five mound appearances and allowed just one earned run in each of his recent three starts.

Kansas City is 4-5 in its last 9 games at home. Moreover, Noah Cameron has only logged a 4.22 ERA over his last five starts and conceded six earned runs in his August 25 start against the Chicago White Sox. Kansas City starters have given up a 6.15 ERA in the last five games, which will only put them in a difficult spot against the Guardians, who are hitting .245 with 5.0 runs per game in their last 10 games.

Our betting prediction for the Kansas City Royals vs. the Cleveland Guardians: the Guardians will win.

Prediction:

 

The Guardians will win

-121
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Kansas City Royals vs Cleveland Guardians Picks