Cincinnati Bearcats vs Iowa State Cyclones Prediction & Picks - NCAA

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Cincinnati Bearcats
10/4/25 12:00
Iowa State Cyclones

Prediction:

 

Iowa State Cyclones ML

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 by Matt Lowrimore | in NCAA Picks

One of the important Big 12 games on the Week 6 college football slate will see the 14th-ranked Iowa State Cyclones take on the Cincinnati Bearcats. Let’s take a look at the match statistics and predictions for this game between the Cyclones and the Bearcats.

Iowa State enters this game with a record of 5-0 and 2-0 in the Big 12. The Cyclones most recently beat the Arizona Wildcats in Week 5 by a score of 39-14. Iowa State’s offense had a total of 399 yards, while its defense allowed 360 yards. Quarterback Rocco Becht threw for 243 yards and one interception, while running back Carson Hansen led the team in rushing with 63 yards and two touchdowns.

As for Cincinnati, they enter this game with a record of 3-1 and 1-0 in the Big 12. The Bearcats most recently beat the Kansas Jayhawks in Week 5 by a score of 37-34. Cincinnati’s offense had a total of 603 yards, while its defense allowed 597 yards. Quarterback Brendan Sorsby threw for 388 yards and two touchdowns, while running back Evan Pryor led the team in rushing with 90 yards.

Cincinnati Bearcats vs Iowa State Cyclones Form

Table

Cincinnati Bearcats and Iowa State Cyclones Latest Matches

Cincinnati Bearcats
Cincinnati Bearcats Latest matches
W L W W W
Victories

4/5 (80%)

Defeats

1/5 (20%)

Sep 27, 2025 - NCAA

Kansas Jayhawks
34 :  37
Cincinnati Bearcats

Sep 13, 2025 - NCAA

Cincinnati Bearcats
70 :  0
Northwestern State Demons

Sep 6, 2025 - NCAA

Cincinnati Bearcats
34 :  20
Bowling Green Falcons

Aug 28, 2025 - NCAA

Cincinnati Bearcats
17 :  20
Nebraska Cornhuskers

Oct 12, 2024 - NCAA

UCF Knights
13 :  19
Cincinnati Bearcats
L W W
Victories

2/3 (67%)

Defeats

1/3 (33%)

Sep 13, 2025 - NCAA

Cincinnati Bearcats
70 :  0
Northwestern State Demons

Sep 6, 2025 - NCAA

Cincinnati Bearcats
34 :  20
Bowling Green Falcons

Aug 28, 2025 - NCAA

Cincinnati Bearcats
17 :  20
Nebraska Cornhuskers
W W
Victories

2/2 (100%)

Defeats

0/2 (0%)

Sep 27, 2025 - NCAA

Kansas Jayhawks
34 :  37
Cincinnati Bearcats

Oct 12, 2024 - NCAA

UCF Knights
13 :  19
Cincinnati Bearcats
Iowa State Cyclones
Iowa State Cyclones Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Sep 27, 2025 - NCAA

Iowa State Cyclones
39 :  14
Arizona Wildcats

Sep 13, 2025 - NCAA

Arkansas State Red Wolves
16 :  24
Iowa State Cyclones

Sep 6, 2025 - NCAA

Iowa State Cyclones
16 :  13
Iowa Hawkeyes

Aug 30, 2025 - NCAA

Iowa State Cyclones
55 :  7
South Dakota Coyotes

Aug 23, 2025 - NCAA

Kansas State Wildcats
21 :  24
Iowa State Cyclones

Oct 19, 2024 - NCAA

Iowa State Cyclones
38 :  35
UCF Knights
W W W W
Victories

4/4 (100%)

Defeats

0/4 (0%)

Sep 27, 2025 - NCAA

Iowa State Cyclones
39 :  14
Arizona Wildcats

Sep 6, 2025 - NCAA

Iowa State Cyclones
16 :  13
Iowa Hawkeyes

Aug 30, 2025 - NCAA

Iowa State Cyclones
55 :  7
South Dakota Coyotes

Oct 19, 2024 - NCAA

Iowa State Cyclones
38 :  35
UCF Knights
W W
Victories

2/2 (100%)

Defeats

0/2 (0%)

Sep 13, 2025 - NCAA

Arkansas State Red Wolves
16 :  24
Iowa State Cyclones

Aug 23, 2025 - NCAA

Kansas State Wildcats
21 :  24
Iowa State Cyclones

Cincinnati Bearcats - Iowa State Cyclones Key Points

  1. Iowa State is 3-2 ATS this season
  2. Iowa State is averaging 31.6 points per game this season
  3. Cincinnati is averaging 39.5 points per game this season
  4. Cincinnati is 3-1 ATS this season

Our Cincinnati Bearcats vs Iowa State Cyclones Prediction

It is strange that Iowa State is the slight underdog, despite being ranked in the top 15 and being undefeated. Cincinnati has certainly recovered from their season-opening loss to Nebraska, but Iowa State will be their toughest test so far this season.

The Cyclones’ defense, in particular, has played excellently this season, allowing an average of 14.2 points per game, while Cincinnati’s defense is allowing an average of 24.7 points per game if you take out their game against an inferior Northwestern State team. 

Overall, Iowa State’s offense has been more consistent, especially with their ability to grind their opponents down; therefore, our Iowa State Cyclones vs Cincinnati Bearcats prediction is: Iowa State Cyclones ML.

Prediction:

 

Iowa State Cyclones ML

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Cincinnati Bearcats vs Iowa State Cyclones Picks