Iowa State Cyclones vs Iowa Hawkeyes Prediction & Picks - NCAA

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Iowa State Cyclones
9/6/25 12:00
Iowa Hawkeyes

Prediction:

 

Iowa State Cyclones ML

-162
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 by Matt Lowrimore | in NCAA Picks

While the Week 2 college football Saturday slate does not have many ranked vs ranked matchups, we will see an intense in-state rivalry game featuring the Iowa Hawkeyes, out of the Big Ten, and the Iowa State Cyclones, out of the Big 12. Let’s take a look at the match statistics and predictions for this game between the Hawkeyes and Cyclones.

Iowa enters this game with a record of 1-0, having beaten the Albany Great Danes in Week 1 by a score of 34-7. The Hawkeyes’ offense had a total of 358 yards, while their defense allowed a total of 177 yards. Quarterback Mark Gronowski threw for 44 yards and a touchdown, while running back Xavier Williams rushed for 122 yards and a touchdown.

As for Iowa State, they enter this game with a record of 2-0, most recently beating the South Dakota Coyotes in Week 1 by a score of 55-7. The Cyclones had 529 yards of offense, while allowing a total of 208 yards. Quarterback Rocco Becht threw for 278 yards and three touchdowns, while Dylan Lee led the team in rushing with 81 yards and one touchdown.

Iowa State Cyclones vs Iowa Hawkeyes Form

Table

Iowa State Cyclones and Iowa Hawkeyes Latest Matches

Iowa State Cyclones
Iowa State Cyclones Latest matches
W W W
Victories

3/3 (100%)

Defeats

0/3 (0%)

Aug 30, 2025 - NCAA

Iowa State Cyclones
55 :  7
South Dakota Coyotes

Aug 23, 2025 - NCAA

Kansas State Wildcats
21 :  24
Iowa State Cyclones

Oct 19, 2024 - NCAA

Iowa State Cyclones
38 :  35
UCF Knights
W W
Victories

2/2 (100%)

Defeats

0/2 (0%)

Aug 30, 2025 - NCAA

Iowa State Cyclones
55 :  7
South Dakota Coyotes

Oct 19, 2024 - NCAA

Iowa State Cyclones
38 :  35
UCF Knights
W
Victories

1/1 (100%)

Defeats

0/1 (0%)

Aug 23, 2025 - NCAA

Kansas State Wildcats
21 :  24
Iowa State Cyclones
Iowa Hawkeyes
Iowa Hawkeyes Latest matches
W
Victories

1/1 (100%)

Defeats

0/1 (0%)

Aug 30, 2025 - NCAA

Iowa Hawkeyes
34 :  7
University At Albany Great Danes
W
Victories

1/1 (100%)

Defeats

0/1 (0%)

Aug 30, 2025 - NCAA

Iowa Hawkeyes
34 :  7
University At Albany Great Danes

Iowa State Cyclones - Iowa Hawkeyes Key Points

  1. The Cyclones are 2-0 ATS this season
  2. The Cyclones are averaging 39.5 points per game this season
  3. The Cyclones are allowing 14 points per game this season
  4. The Hawkeyes forced two turnovers in Week 1

Our Iowa State Cyclones vs Iowa Hawkeyes Prediction

One of the major problems with Iowa over the past several seasons has been its ability to score points consistently. The Hawkeyes did score 34 points in their season opener, but considering this was against Albany, it is fair to expect much less from them against Iowa State.

As for Iowa State, they have already been tested this season, beating Kansas State in Ireland in Week 0 before crushing South Dakota in Week 1. Despite their lack of competition in Week 1, the Cyclones are averaging nearly 40 points per game, while their defense has allowed an average of 14 points per game.

Despite their general lack of offense, Iowa’s defense tends to be very good. Because of that, a low-scoring game should be expected in this rivalry game. However, even if this game is low scoring, because the Cyclones’ offense has looked extremely efficient through the first couple of weeks, our Iowa Hawkeyes vs Iowa State Cyclones prediction is: Iowa State Cyclones ML.

Prediction:

 

Iowa State Cyclones ML

-162
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Iowa State Cyclones vs Iowa Hawkeyes Picks