Iowa Hawkeyes vs Iowa State Cyclones Prediction & Picks - NCAA

USA - NCAA

Iowa Hawkeyes
9/6/25 12:00
Iowa State Cyclones

Prediction:

 

Iowa State Cyclones ML

-162
$500+ offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Matt Lowrimore in NCAA Picks

While the Week 2 college football Saturday slate does not have many ranked vs ranked matchups, we will see an intense in-state rivalry game featuring the Iowa Hawkeyes, out of the Big Ten, and the Iowa State Cyclones, out of the Big 12. Let’s take a look at the match statistics and predictions for this game between the Hawkeyes and Cyclones.

Iowa enters this game with a record of 1-0, having beaten the Albany Great Danes in Week 1 by a score of 34-7. The Hawkeyes’ offense had a total of 358 yards, while their defense allowed a total of 177 yards. Quarterback Mark Gronowski threw for 44 yards and a touchdown, while running back Xavier Williams rushed for 122 yards and a touchdown.

As for Iowa State, they enter this game with a record of 2-0, most recently beating the South Dakota Coyotes in Week 1 by a score of 55-7. The Cyclones had 529 yards of offense, while allowing a total of 208 yards. Quarterback Rocco Becht threw for 278 yards and three touchdowns, while Dylan Lee led the team in rushing with 81 yards and one touchdown.

Iowa Hawkeyes vs Iowa State Cyclones Form

Table

Teams % P W D L
1
Iowa State Cyclones
Iowa State Cyclones
1000 1 1 0 0
66
Iowa Hawkeyes
Iowa Hawkeyes
1000 1 1 0 0

Iowa Hawkeyes and Iowa State Cyclones Latest Matches

Iowa Hawkeyes
Iowa Hawkeyes Latest matches
W L W W L W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Aug 30, 2025 - NCAA

University At Albany Great Danes
7 :  34
Iowa Hawkeyes

Dec 30, 2024 - NCAA Division I, FBS, Playoffs

Iowa Hawkeyes
24 :  27
Missouri Tigers

Nov 29, 2024 - NCAA

Nebraska Cornhuskers
10 :  13
Iowa Hawkeyes

Nov 23, 2024 - NCAA

Iowa Hawkeyes
29 :  13
Maryland Terrapins

Nov 8, 2024 - NCAA

Iowa Hawkeyes
17 :  20
UCLA Bruins

Nov 2, 2024 - NCAA

Wisconsin Badgers
10 :  42
Iowa Hawkeyes
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Aug 30, 2025 - NCAA

University At Albany Great Danes
7 :  34
Iowa Hawkeyes

Nov 29, 2024 - NCAA

Nebraska Cornhuskers
10 :  13
Iowa Hawkeyes

Nov 2, 2024 - NCAA

Wisconsin Badgers
10 :  42
Iowa Hawkeyes

Oct 26, 2024 - NCAA

Northwestern Wildcats
14 :  40
Iowa Hawkeyes

Oct 12, 2024 - NCAA

Washington Huskies
16 :  40
Iowa Hawkeyes

Sep 14, 2024 - NCAA

Troy Trojans
21 :  38
Iowa Hawkeyes
W L L L W L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Dec 30, 2024 - NCAA Division I, FBS, Playoffs

Iowa Hawkeyes
24 :  27
Missouri Tigers

Nov 23, 2024 - NCAA

Iowa Hawkeyes
29 :  13
Maryland Terrapins

Nov 8, 2024 - NCAA

Iowa Hawkeyes
17 :  20
UCLA Bruins

Oct 19, 2024 - NCAA

Iowa Hawkeyes
20 :  32
Michigan State Spartans

Oct 5, 2024 - NCAA

Iowa Hawkeyes
7 :  35
Ohio State Buckeyes

Sep 21, 2024 - NCAA

Iowa Hawkeyes
31 :  14
Minnesota Golden Gophers
Iowa State Cyclones
Iowa State Cyclones Latest matches
W W L W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Aug 30, 2025 - NCAA

South Dakota Coyotes
7 :  55
Iowa State Cyclones

Aug 23, 2025 - NCAA

Iowa State Cyclones
24 :  21
Kansas State Wildcats

Dec 28, 2024 - NCAA Division I, FBS, Playoffs

Iowa State Cyclones
42 :  41
Miami (FL) Hurricanes

Dec 7, 2024 - NCAA

Iowa State Cyclones
19 :  45
Arizona State Sun Devils

Nov 30, 2024 - NCAA

Kansas State Wildcats
21 :  29
Iowa State Cyclones

Nov 23, 2024 - NCAA

Iowa State Cyclones
31 :  28
Utah Utes
W W L W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Aug 30, 2025 - NCAA

South Dakota Coyotes
7 :  55
Iowa State Cyclones

Nov 30, 2024 - NCAA

Kansas State Wildcats
21 :  29
Iowa State Cyclones

Nov 16, 2024 - NCAA

Cincinnati Bearcats
17 :  34
Iowa State Cyclones

Nov 2, 2024 - NCAA

Texas Tech Red Raiders
23 :  22
Iowa State Cyclones

Oct 19, 2024 - NCAA

UCF Knights
35 :  38
Iowa State Cyclones

Oct 5, 2024 - NCAA

Baylor Bears
21 :  43
Iowa State Cyclones
W L W L W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Aug 23, 2025 - NCAA

Iowa State Cyclones
24 :  21
Kansas State Wildcats

Dec 28, 2024 - NCAA Division I, FBS, Playoffs

Iowa State Cyclones
42 :  41
Miami (FL) Hurricanes

Dec 7, 2024 - NCAA

Iowa State Cyclones
19 :  45
Arizona State Sun Devils

Nov 23, 2024 - NCAA

Iowa State Cyclones
31 :  28
Utah Utes

Nov 9, 2024 - NCAA

Iowa State Cyclones
36 :  45
Kansas Jayhawks

Oct 12, 2024 - NCAA

Iowa State Cyclones
28 :  16
West Virginia Mountaineers

Iowa Hawkeyes against Iowa State Cyclones : Head to Head (H2H)

Sep 7, 2024 - NCAA

Iowa State Cyclones
20 :  19
Iowa Hawkeyes

Iowa Hawkeyes - Iowa State Cyclones Key Points

  1. The Cyclones are 2-0 ATS this season
  2. The Cyclones are averaging 39.5 points per game this season
  3. The Cyclones are allowing 14 points per game this season
  4. The Hawkeyes forced two turnovers in Week 1

Our Iowa Hawkeyes vs Iowa State Cyclones Prediction

One of the major problems with Iowa over the past several seasons has been its ability to score points consistently. The Hawkeyes did score 34 points in their season opener, but considering this was against Albany, it is fair to expect much less from them against Iowa State.

As for Iowa State, they have already been tested this season, beating Kansas State in Ireland in Week 0 before crushing South Dakota in Week 1. Despite their lack of competition in Week 1, the Cyclones are averaging nearly 40 points per game, while their defense has allowed an average of 14 points per game.

Despite their general lack of offense, Iowa’s defense tends to be very good. Because of that, a low-scoring game should be expected in this rivalry game. However, even if this game is low scoring, because the Cyclones’ offense has looked extremely efficient through the first couple of weeks, our Iowa Hawkeyes vs Iowa State Cyclones prediction is: Iowa State Cyclones ML.

Prediction:

 

Iowa State Cyclones ML

-162
$500+ offered for betting!

Jackpot Pools

DK Jackpot Pools

DraftKings's long-running promo Jackpot Pools gives bettors a chance to win a whopping $10,000 which grows with every entry! 

To win, you'll need to answer all 15 questions correctly and the pool is yours! If there are multiple winners, the pool will be split. If no one wins, however, the jackpot rolls over to the next pool, increasing the winnings. You can enter up to 10 times each pool to give yourself an even greater chance of winning. Once the event has completed, you can collect your winnings within 24 hours so keep an eye on the pool! Don't miss out on your chance to win big and make your picks today!

Get started today!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Iowa Hawkeyes vs Iowa State Cyclones Picks