Pittsburgh Steelers vs Indianapolis Colts Prediction & Picks - NFL
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by Dan Angell | in NFL Picks
The Indianapolis Colts face the Pittsburgh Steelers in a matchup of two teams that nobody really expected to be as good as they are. Indianapolis in particular has been a surprise, in large part because of the emergence of Daniel Jones. The Colts’ offense has been one of their strongest features, as they’ve scored at least 29 points in every win this season.
Only a loss to the Rams in Week 4 saw the Colts struggle on offense, and even then, the defense did enough to give the team a chance. Put simply, if the Colts manage to score 28 points, they win the game, as that has been true in every game they’ve played in 2025. They’re coming off four straight where not only did they hit that number, but they went into the 30s.
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Pittsburgh Steelers vs Indianapolis Colts Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
12
|
0.588 | 17 | 10 | 7 |
|
20
|
0.471 | 17 | 8 | 9 |
Pittsburgh Steelers and Indianapolis Colts Latest Matches
3/6 (50%)
3/6 (50%)
Oct 26, 2025 - NFL
Oct 16, 2025 - NFL
Oct 12, 2025 - NFL
Sep 28, 2025 - NFL
Sep 21, 2025 - NFL
Sep 14, 2025 - NFL
2/6 (33%)
4/6 (67%)
Oct 26, 2025 - NFL
Oct 12, 2025 - NFL
Sep 28, 2025 - NFL
Sep 14, 2025 - NFL
Jan 4, 2025 - NFL
Dec 25, 2024 - NFL
2/6 (33%)
4/6 (67%)
Oct 16, 2025 - NFL
Sep 21, 2025 - NFL
Sep 7, 2025 - NFL
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Dec 21, 2024 - NFL
Dec 15, 2024 - NFL
5/6 (83%)
1/6 (17%)
Oct 26, 2025 - NFL
Oct 19, 2025 - NFL
Oct 12, 2025 - NFL
Oct 5, 2025 - NFL
Sep 28, 2025 - NFL
Sep 21, 2025 - NFL
6/6 (100%)
0/6 (0%)
Oct 26, 2025 - NFL
Oct 12, 2025 - NFL
Oct 5, 2025 - NFL
Sep 14, 2025 - NFL
Sep 7, 2025 - NFL
Jan 5, 2025 - NFL
3/6 (50%)
3/6 (50%)
Oct 19, 2025 - NFL
Sep 28, 2025 - NFL
Sep 21, 2025 - NFL
Dec 29, 2024 - NFL
Dec 15, 2024 - NFL
Dec 1, 2024 - NFL
Pittsburgh Steelers against Indianapolis Colts : Head to Head (H2H)
33 %
67 %
Sep 29, 2024 - NFL
Dec 16, 2023 - NFL
Nov 28, 2022 - NFL
Pittsburgh Steelers - Indianapolis Colts Key Points
- The over is 5-2 in Indianapolis’ past seven games.
- The Steelers have allowed 30 points four times this season.
- The Colts have scored 31 points or more in five of six games.
- The over is 5-2 in the Steelers’ past seven games.
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Our Pittsburgh Steelers vs Indianapolis Colts Prediction
Pittsburgh has fallen back to earth after the past two games, and there are now realistic questions about whether the Steelers are as good as their record. The defense in particular is full of question marks, as Pittsburgh has now allowed 68 points in the past two weeks. Granted, Green Bay and Cincinnati can do that to almost anyone, but the only team the Steelers have beaten with a winning record is New England.
Even that has an asterisk, because that came in Week 3 when the Patriots were still finding themselves. The Steelers don’t do enough on defense, and the offense isn’t quite good enough to match with a team that can really score. Indianapolis can score with the best of them, especially this season. Our prediction for Indianapolis vs. Pittsburgh is Colts -3.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
