Indianapolis Colts vs Pittsburgh Steelers Prediction & Picks - NFL

USA - NFL

Indianapolis Colts
11/2/25 13:00
Pittsburgh Steelers

Prediction:

 

Colts -3

-112
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 by Dan Angell | in NFL Picks

The Indianapolis Colts face the Pittsburgh Steelers in a matchup of two teams that nobody really expected to be as good as they are. Indianapolis in particular has been a surprise, in large part because of the emergence of Daniel Jones. The Colts’ offense has been one of their strongest features, as they’ve scored at least 29 points in every win this season.

Only a loss to the Rams in Week 4 saw the Colts struggle on offense, and even then, the defense did enough to give the team a chance. Put simply, if the Colts manage to score 28 points, they win the game, as that has been true in every game they’ve played in 2025. They’re coming off four straight where not only did they hit that number, but they went into the 30s.

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Indianapolis Colts vs Pittsburgh Steelers Form

Table

Teams % P W D L
5
Indianapolis Colts
Indianapolis Colts
0.8 10 8 0 2
13
Pittsburgh Steelers
Pittsburgh Steelers
0.6 10 6 0 4

Indianapolis Colts and Pittsburgh Steelers Latest Matches

Indianapolis Colts
Indianapolis Colts Latest matches
W W L W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Oct 26, 2025 - NFL

Tennessee Titans
14 :  38
Indianapolis Colts

Oct 19, 2025 - NFL

Indianapolis Colts
38 :  24
Los Angeles Chargers

Oct 12, 2025 - NFL

Arizona Cardinals
27 :  31
Indianapolis Colts

Oct 5, 2025 - NFL

Las Vegas Raiders
6 :  40
Indianapolis Colts

Sep 28, 2025 - NFL

Indianapolis Colts
20 :  27
Los Angeles Rams

Sep 21, 2025 - NFL

Indianapolis Colts
41 :  20
Tennessee Titans
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Oct 26, 2025 - NFL

Tennessee Titans
14 :  38
Indianapolis Colts

Oct 12, 2025 - NFL

Arizona Cardinals
27 :  31
Indianapolis Colts

Oct 5, 2025 - NFL

Las Vegas Raiders
6 :  40
Indianapolis Colts

Sep 14, 2025 - NFL

Denver Broncos
28 :  29
Indianapolis Colts

Sep 7, 2025 - NFL

Miami Dolphins
8 :  33
Indianapolis Colts

Jan 5, 2025 - NFL

Jacksonville Jaguars
23 :  26
Indianapolis Colts
W L L W L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Oct 19, 2025 - NFL

Indianapolis Colts
38 :  24
Los Angeles Chargers

Sep 28, 2025 - NFL

Indianapolis Colts
20 :  27
Los Angeles Rams

Sep 21, 2025 - NFL

Indianapolis Colts
41 :  20
Tennessee Titans

Dec 29, 2024 - NFL

Indianapolis Colts
33 :  45
New York Giants

Dec 15, 2024 - NFL

Indianapolis Colts
13 :  31
Denver Broncos

Dec 1, 2024 - NFL

Indianapolis Colts
25 :  24
New England Patriots
Pittsburgh Steelers
Pittsburgh Steelers Latest matches
W L W W W L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Oct 26, 2025 - NFL

Green Bay Packers
35 :  25
Pittsburgh Steelers

Oct 16, 2025 - NFL

Pittsburgh Steelers
31 :  33
Cincinnati Bengals

Oct 12, 2025 - NFL

Cleveland Browns
9 :  23
Pittsburgh Steelers

Sep 28, 2025 - NFL

Minnesota Vikings
21 :  24
Pittsburgh Steelers

Sep 21, 2025 - NFL

Pittsburgh Steelers
21 :  14
New England Patriots

Sep 14, 2025 - NFL

Seattle Seahawks
31 :  17
Pittsburgh Steelers
W L L L W W
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Oct 26, 2025 - NFL

Green Bay Packers
35 :  25
Pittsburgh Steelers

Oct 12, 2025 - NFL

Cleveland Browns
9 :  23
Pittsburgh Steelers

Sep 28, 2025 - NFL

Minnesota Vikings
21 :  24
Pittsburgh Steelers

Sep 14, 2025 - NFL

Seattle Seahawks
31 :  17
Pittsburgh Steelers

Jan 4, 2025 - NFL

Cincinnati Bengals
19 :  17
Pittsburgh Steelers

Dec 25, 2024 - NFL

Kansas City Chiefs
29 :  10
Pittsburgh Steelers
L L L W W L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Oct 16, 2025 - NFL

Pittsburgh Steelers
31 :  33
Cincinnati Bengals

Sep 21, 2025 - NFL

Pittsburgh Steelers
21 :  14
New England Patriots

Sep 7, 2025 - NFL

Pittsburgh Steelers
34 :  32
New York Jets

Jan 11, 2025 - NFL

Pittsburgh Steelers
14 :  28
Baltimore Ravens

Dec 21, 2024 - NFL

Pittsburgh Steelers
17 :  34
Baltimore Ravens

Dec 15, 2024 - NFL

Pittsburgh Steelers
13 :  27
Philadelphia Eagles

Indianapolis Colts against Pittsburgh Steelers : Head to Head (H2H)

Indianapolis Colts

67 %

Draw

0 %

Pittsburgh Steelers

33 %

Sep 29, 2024 - NFL

Pittsburgh Steelers
24 :  27
Indianapolis Colts

Dec 16, 2023 - NFL

Pittsburgh Steelers
13 :  30
Indianapolis Colts

Nov 28, 2022 - NFL

Pittsburgh Steelers
24 :  17
Indianapolis Colts

Indianapolis Colts - Pittsburgh Steelers Key Points

  1. The over is 5-2 in Indianapolis’ past seven games.
  2. The Steelers have allowed 30 points four times this season.
  3. The Colts have scored 31 points or more in five of six games.
  4. The over is 5-2 in the Steelers’ past seven games.
Up to $500+ to bet on Indianapolis Colts - Pittsburgh Steelers! 

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Our Indianapolis Colts vs Pittsburgh Steelers Prediction

Pittsburgh has fallen back to earth after the past two games, and there are now realistic questions about whether the Steelers are as good as their record. The defense in particular is full of question marks, as Pittsburgh has now allowed 68 points in the past two weeks. Granted, Green Bay and Cincinnati can do that to almost anyone, but the only team the Steelers have beaten with a winning record is New England.

Even that has an asterisk, because that came in Week 3 when the Patriots were still finding themselves. The Steelers don’t do enough on defense, and the offense isn’t quite good enough to match with a team that can really score. Indianapolis can score with the best of them, especially this season. Our prediction for Indianapolis vs. Pittsburgh is Colts -3.

Prediction:

 

Colts -3

-112
$500+ offered for betting!

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Indianapolis Colts vs Pittsburgh Steelers Picks