Houston Texans vs Indianapolis Colts Prediction & Picks - NFL

USA - NFL

Houston Texans
1/4/26 13:00
Indianapolis Colts

Prediction:

 

Colts +10

-105
$300 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Dan Angell | in NFL Picks

The Houston Texans host the Indianapolis Colts in an AFC South matchup between two teams htat have headed in vastly different directions. The Colts started the year 8-2, seemingly on track to return to the playoffs and make a real run at the No. 1 seed. Instead, Indianapolis is now 8-8, losers of six straight and guaranteed to miss the playoffs again.

The Texans, on the other hand, are once again in the playoffs. However, Houston doesn’t know where it’s going to be playing just yet. The Texans can seal no worse than the No. 5 seed by beating Indianapolis, and if Tennessee can somehow upset equally-hot Jacksonville, the Texans would win the AFC South and host a playoff game. If, as expected, the Titans don’t provide help, Houston will be on its way to either Pittsburgh or Baltimore with a win.

Houston Texans vs Indianapolis Colts Form

Table

Teams Pts P W L
6
Houston Texans
Houston Texans
0.706 17 12 5
20
Indianapolis Colts
Indianapolis Colts
0.471 17 8 9

Houston Texans and Indianapolis Colts Latest Matches

Houston Texans
Houston Texans Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Dec 27, 2025 - NFL

Los Angeles Chargers
16 :  20
Houston Texans

Dec 21, 2025 - NFL

Houston Texans
23 :  21
Las Vegas Raiders

Dec 14, 2025 - NFL

Houston Texans
40 :  20
Arizona Cardinals

Dec 7, 2025 - NFL

Kansas City Chiefs
10 :  20
Houston Texans

Nov 30, 2025 - NFL

Indianapolis Colts
16 :  20
Houston Texans

Nov 20, 2025 - NFL

Houston Texans
23 :  19
Buffalo Bills
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Dec 21, 2025 - NFL

Houston Texans
23 :  21
Las Vegas Raiders

Dec 14, 2025 - NFL

Houston Texans
40 :  20
Arizona Cardinals

Nov 20, 2025 - NFL

Houston Texans
23 :  19
Buffalo Bills

Nov 9, 2025 - NFL

Houston Texans
36 :  29
Jacksonville Jaguars

Nov 2, 2025 - NFL

Houston Texans
15 :  18
Denver Broncos

Oct 26, 2025 - NFL

Houston Texans
26 :  15
San Francisco 49ers
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Dec 27, 2025 - NFL

Los Angeles Chargers
16 :  20
Houston Texans

Dec 7, 2025 - NFL

Kansas City Chiefs
10 :  20
Houston Texans

Nov 30, 2025 - NFL

Indianapolis Colts
16 :  20
Houston Texans

Nov 16, 2025 - NFL

Tennessee Titans
13 :  16
Houston Texans

Oct 20, 2025 - NFL

Seattle Seahawks
27 :  19
Houston Texans

Oct 5, 2025 - NFL

Baltimore Ravens
10 :  44
Houston Texans
Indianapolis Colts
Indianapolis Colts Latest matches
L L L L L L
Victories

0/6 (0%)

Defeats

6/6 (100%)

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 22, 2025 - NFL

Indianapolis Colts
27 :  48
San Francisco 49ers

Dec 14, 2025 - NFL

Seattle Seahawks
18 :  16
Indianapolis Colts

Dec 7, 2025 - NFL

Jacksonville Jaguars
36 :  19
Indianapolis Colts

Nov 30, 2025 - NFL

Indianapolis Colts
16 :  20
Houston Texans

Nov 23, 2025 - NFL

Kansas City Chiefs
23 :  20
Indianapolis Colts
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Dec 28, 2025 - NFL

Indianapolis Colts
17 :  23
Jacksonville Jaguars

Dec 22, 2025 - NFL

Indianapolis Colts
27 :  48
San Francisco 49ers

Nov 30, 2025 - NFL

Indianapolis Colts
16 :  20
Houston Texans

Nov 9, 2025 - NFL

Indianapolis Colts
31 :  25
Atlanta Falcons

Oct 26, 2025 - NFL

Indianapolis Colts
38 :  14
Tennessee Titans

Oct 12, 2025 - NFL

Indianapolis Colts
31 :  27
Arizona Cardinals
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Dec 14, 2025 - NFL

Seattle Seahawks
18 :  16
Indianapolis Colts

Dec 7, 2025 - NFL

Jacksonville Jaguars
36 :  19
Indianapolis Colts

Nov 23, 2025 - NFL

Kansas City Chiefs
23 :  20
Indianapolis Colts

Nov 2, 2025 - NFL

Pittsburgh Steelers
27 :  20
Indianapolis Colts

Oct 19, 2025 - NFL

Los Angeles Chargers
24 :  38
Indianapolis Colts

Sep 28, 2025 - NFL

Los Angeles Rams
27 :  20
Indianapolis Colts

Houston Texans against Indianapolis Colts : Head to Head (H2H)

Houston Texans

80 %

Indianapolis Colts

20 %

Nov 30, 2025 - NFL

Indianapolis Colts
16 :  20
Houston Texans

Oct 27, 2024 - NFL

Houston Texans
23 :  20
Indianapolis Colts

Sep 8, 2024 - NFL

Indianapolis Colts
27 :  29
Houston Texans

Jan 6, 2024 - NFL

Indianapolis Colts
19 :  23
Houston Texans

Sep 17, 2023 - NFL

Houston Texans
20 :  31
Indianapolis Colts

Houston Texans - Indianapolis Colts Key Points

  1. The Texans have won five of six against the Colts.
  2. The visiting team has covered in six of the past eight meetings.
  3. The Colts are 1-7 in their past eight games.
  4. The Texans have won their past eight games.

Our Houston Texans vs Indianapolis Colts Prediction

That Houston’s going to win this game isn’t really in question. Indianapolis has been running on fumes ever since Daniel Jones tore his Achilles against Jacksonville. The Colts lost that game in blowout fashion, but they have played hard even without Jones. They fell to Seattle and Jacksonville by one possession each, and the three-touchdown loss to San Francisco happened because Philip Rivers got aggressive trying to bring the Colts back and threw a pick-six.

Houston doesn’t blow teams out. The Texans have kept winning, but they allow teams to hang around with them far longer than they should. Only Arizona, which hasn’t done anything at all since Week 2, lost to Houston by more than 10 points. The Texans have faced truly awful teams in Las Vegas and Tennessee, and won those two games by a combined five points. That says this spread is far too high. Indianapolis is almost certainly going to lose, but the Colts should make the Texans work. Our prediction for Indianapolis vs. Houston is Colts +10.

Prediction:

 

Colts +10

-105
$300 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Houston Texans vs Indianapolis Colts Picks