Indianapolis Colts vs Houston Texans Prediction & Picks - NFL

USA - NFL

Indianapolis Colts
11/30/25 13:00
Houston Texans

Prediction:

 

Under 44.5

-110
$200 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Bill Christy | in NFL Picks

The top team in the AFC South will look to stay there this Sunday. The Indianapolis Colts (8-3) are that team and will be taking on the Houston Texans (6-5) in a divisional matchup. This will be the 1st of two meetings between the foes this season.

The Colts are coming off a rough 23-20 overtime loss to the Kansas City Chiefs last week. The loss was their 2nd in the last 3 games and may be showing some cracks in a team that many were touting as the favorites to win the AFC just a few short weeks ago. Jonathan Taylor was held to just 58 rushing yards in the loss, while no receiver surpassed 50 yards receiving. The defense allowed nearly 500 total yards, and while they held tight in the red zone, it was not enough to get the win.

Houston has won 3 games in a row after defeating the Bills last week. Davis Mills has been tremendous in replacing the injured CJ Stroud. He has thrown 5 touchdowns and just 1 interception over that 3-game winning streak. However, the defense was key in the last win as they held Josh Allen to just under 200 yards passing and picked him off twice.

If the Houston defense can replicate the efforts from last week, they could push this Colts team to the limit here on the road.

Indianapolis Colts vs Houston Texans Form

Table

Teams Pts P W L
6 Houston Texans
0.706 17 12 5
20 Indianapolis Colts
0.471 17 8 9

Indianapolis Colts and Houston Texans Latest Matches

Indianapolis Colts
Indianapolis Colts Latest matches
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 23, 2025 - NFL

Kansas City Chiefs
23 :  20
Indianapolis Colts

Nov 9, 2025 - NFL

Indianapolis Colts
31 :  25
Atlanta Falcons

Nov 2, 2025 - NFL

Pittsburgh Steelers
27 :  20
Indianapolis Colts

Oct 26, 2025 - NFL

Indianapolis Colts
38 :  14
Tennessee Titans

Oct 19, 2025 - NFL

Los Angeles Chargers
24 :  38
Indianapolis Colts

Oct 12, 2025 - NFL

Indianapolis Colts
31 :  27
Arizona Cardinals
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Nov 9, 2025 - NFL

Indianapolis Colts
31 :  25
Atlanta Falcons

Oct 26, 2025 - NFL

Indianapolis Colts
38 :  14
Tennessee Titans

Oct 12, 2025 - NFL

Indianapolis Colts
31 :  27
Arizona Cardinals

Oct 5, 2025 - NFL

Indianapolis Colts
40 :  6
Las Vegas Raiders

Sep 14, 2025 - NFL

Indianapolis Colts
29 :  28
Denver Broncos

Sep 7, 2025 - NFL

Indianapolis Colts
33 :  8
Miami Dolphins
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 23, 2025 - NFL

Kansas City Chiefs
23 :  20
Indianapolis Colts

Nov 2, 2025 - NFL

Pittsburgh Steelers
27 :  20
Indianapolis Colts

Oct 19, 2025 - NFL

Los Angeles Chargers
24 :  38
Indianapolis Colts

Sep 28, 2025 - NFL

Los Angeles Rams
27 :  20
Indianapolis Colts

Sep 21, 2025 - NFL

Tennessee Titans
20 :  41
Indianapolis Colts

Dec 29, 2024 - NFL

New York Giants
45 :  33
Indianapolis Colts
Houston Texans
Houston Texans Latest matches
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 20, 2025 - NFL

Houston Texans
23 :  19
Buffalo Bills

Nov 16, 2025 - NFL

Tennessee Titans
13 :  16
Houston Texans

Nov 9, 2025 - NFL

Houston Texans
36 :  29
Jacksonville Jaguars

Nov 2, 2025 - NFL

Houston Texans
15 :  18
Denver Broncos

Oct 26, 2025 - NFL

Houston Texans
26 :  15
San Francisco 49ers

Oct 20, 2025 - NFL

Seattle Seahawks
27 :  19
Houston Texans
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 20, 2025 - NFL

Houston Texans
23 :  19
Buffalo Bills

Nov 9, 2025 - NFL

Houston Texans
36 :  29
Jacksonville Jaguars

Nov 2, 2025 - NFL

Houston Texans
15 :  18
Denver Broncos

Oct 26, 2025 - NFL

Houston Texans
26 :  15
San Francisco 49ers

Sep 28, 2025 - NFL

Houston Texans
26 :  0
Tennessee Titans

Sep 15, 2025 - NFL

Houston Texans
19 :  20
Tampa Bay Buccaneers
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 16, 2025 - NFL

Tennessee Titans
13 :  16
Houston Texans

Oct 20, 2025 - NFL

Seattle Seahawks
27 :  19
Houston Texans

Oct 5, 2025 - NFL

Baltimore Ravens
10 :  44
Houston Texans

Sep 21, 2025 - NFL

Jacksonville Jaguars
17 :  10
Houston Texans

Sep 7, 2025 - NFL

Los Angeles Rams
14 :  9
Houston Texans

Jan 18, 2025 - NFL

Kansas City Chiefs
23 :  14
Houston Texans

Indianapolis Colts against Houston Texans : Head to Head (H2H)

Indianapolis Colts

25 %

Houston Texans

75 %

Oct 27, 2024 - NFL

Houston Texans
23 :  20
Indianapolis Colts

Sep 8, 2024 - NFL

Indianapolis Colts
27 :  29
Houston Texans

Jan 6, 2024 - NFL

Indianapolis Colts
19 :  23
Houston Texans

Sep 17, 2023 - NFL

Houston Texans
20 :  31
Indianapolis Colts

Indianapolis Colts - Houston Texans Key Points

  1. The total has gone UNDER in 7 of Houston’s last 10 games.
  2. The total has gone UNDER in 4 of Houston’s last 5 games when playing as the underdog.
  3. The total has gone UNDER in 7 of Indianapolis’ last 10 games against Houston.
  4. The total has gone UNDER in 12 of Indianapolis’ last 16 games when playing at home against Houston.

Our Indianapolis Colts vs Houston Texans Prediction

While the spread does indicate to us that Houston could be the play, it also tells us that the total is likely going to the under. The Texans will not be able to keep the game close if they are planning on trying to keep pace with the Colts offense. Instead, we believe they will keep this one close by keeping the total under the number.

Our prediction for Indianapolis Colts vs Houston Texans: Under 44.5

Prediction:

 

Under 44.5

-110
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Indianapolis Colts vs Houston Texans Picks