Iowa St. vs Houston Prediction & Picks - NCAA Men

USA - NCAA Men

Iowa St.
2/16/26 21:00
Houston

Prediction:

 

UNDER 133.5

-110
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 by Travis Pulver | in Basketball Picks

The No. 5 Iowa State Cyclones will try to keep the good times rolling after their weekend win over No. 9 Kansas when they host the No. 3 Houston Cougars at the Hilton Coliseum in Ames, IA. Gametime for this Big 12/Top five showdown is scheduled for 9 p.m. EST on Monday, February 16, with coverage provided by ESPN.

Kansas had been on a roll before running into the Cyclones on Saturday, winners of eight in a row (a streak that started with a win over then-No. 2 Iowa State at home). Despite their impressive run, the home team, the Cyclones, were 7.5-point favorites in a game that was never close. Iowa State led by ten at the half, 37-27, and went on to win by 18, 74-56, while holding Kansas to 37% shooting from the floor and 33% from three-point range. As for Houston, the Cougars extended their winning streak to six in a row with a 14-point win over Kansas State. The Cougars led by 14 at the half, 33-19, and cruised through the second, 45-45, to make the final score 78-64.

This game kicks off a three-game stretch for Houston against ranked teams with Arizona and Kansas to follow. It marks the beginning of a tough stretch to the end of the regular season for Iowa State as they face ranked teams in four of their last six games.

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Iowa St. vs Houston Form

Table

Teams % P W L Series
13 Houston
0.839 31 26 5 3
19 Iowa St.
0.806 31 25 6 1

Iowa St. and Houston Latest Matches

Iowa St.
Iowa St. Latest matches
W L W L
Victories

2/4 (50%)

Defeats

2/4 (50%)

Mar 23, 2025 - NCAA Basketball

Iowa St.
78 :  91
Ole Miss Rebels

Mar 21, 2025 - NCAA Basketball

Iowa St.
82 :  55
Lipscomb Bisons

Mar 28, 2024 - NCAA Basketball

Iowa St.
69 :  72
Illinois

Mar 23, 2024 - NCAA Basketball

Iowa St.
67 :  56
Wash. St.
W L W L
Victories

2/4 (50%)

Defeats

2/4 (50%)

Mar 23, 2025 - NCAA Basketball

Iowa St.
78 :  91
Ole Miss Rebels

Mar 21, 2025 - NCAA Basketball

Iowa St.
82 :  55
Lipscomb Bisons

Mar 28, 2024 - NCAA Basketball

Iowa St.
69 :  72
Illinois

Mar 23, 2024 - NCAA Basketball

Iowa St.
67 :  56
Wash. St.
Houston
Houston Latest matches
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 7, 2025 - NCAA Basketball

Houston
63 :  65
Florida

Apr 5, 2025 - NCAA Basketball

Duke
67 :  70
Houston

Mar 30, 2025 - NCAA Basketball

Houston
69 :  50
Tennessee

Mar 22, 2025 - NCAA Basketball

Houston
81 :  76
Gonzaga

Mar 20, 2025 - NCAA Basketball

Houston
78 :  40
SIU Edwardsville Cougars

Mar 29, 2024 - NCAA Basketball

Houston
51 :  54
Duke
L W W W L
Victories

3/5 (60%)

Defeats

2/5 (40%)

Apr 7, 2025 - NCAA Basketball

Houston
63 :  65
Florida

Mar 30, 2025 - NCAA Basketball

Houston
69 :  50
Tennessee

Mar 22, 2025 - NCAA Basketball

Houston
81 :  76
Gonzaga

Mar 20, 2025 - NCAA Basketball

Houston
78 :  40
SIU Edwardsville Cougars

Mar 29, 2024 - NCAA Basketball

Houston
51 :  54
Duke
W
Victories

1/1 (100%)

Defeats

0/1 (0%)

Apr 5, 2025 - NCAA Basketball

Duke
67 :  70
Houston

Iowa St. - Houston Key Points

  1. The all-time series between Houston and Iowa State is tied at 5-5, but Houston has won two of the last three meetings.
  2. Iowa State is 10-7 ATS at home; Houston is 5-3 ATS on the road.
  3. The OVER is 8-9 for Iowa State at home and 4-4 for Houston on the road.
  4. Iowa State is 14-0 when favored at home; Houston is 5-1 on the road but has not been an underdog this season.
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Our Iowa St. vs Houston Prediction

I’m assuming Iowa State is the favorite in this game simply because they are the home team, but this one should have been a pick’em. Both teams have fantastic lockdown defenses. That was evident when Iowa State held Kansas to just 56 points. Houston has held three of its last five opponents to under 60 points; the other two scored 66 and 64. Both are capable on the offensive end, but this is clearly going to be a defensive battle and a low-scoring game.

Our Houston vs. Iowa State Pick: UNDER 133.5

Prediction:

 

UNDER 133.5

-110
$350 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Iowa St. vs Houston Picks