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by Lou Aguila in MLB Picks
The Houston Astros and the St. Louis Cardinals clash in a three-game series at Busch Stadium starting Monday.
The Astros escaped with a series win over the Los Angeles Angels after blasting them 7-3 on Sunday. Averaging 5.9 runs per game in their last five, Houston scored five runs in the second innings and added two more in the sixth and seventh to get a “feel good” win after scoring only one run in Game 2. The Astros are batting .219 with 60 runs and pitching a 3.69 ERA this season.
The Cardinals are also fresh off a series win after shutting the light out of the Philadelphia 7-0 in Game 3 on Sunday. St. Louis, who holds a team ERA of 4.48 this season, secured their second shutout win over Philadelphia thanks to a near-flawless outing from Matthew Laberatore and a much-improved bullpen that has allowed 1.40 ERA in the last five games.
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Houston Astros vs St. Louis Cardinals Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
12
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0.533 | 30 | 16 | 14 |
22
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0.438 | 32 | 14 | 18 |
Houston Astros and St. Louis Cardinals Latest Matches

3/6 (50%)
3/6 (50%)
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 3, 2025 - MLB

3/6 (50%)
3/6 (50%)
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
1/6 (17%)
5/6 (83%)
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Houston Astros against St. Louis Cardinals : Head to Head (H2H)
83 %
17 %
Mar 21, 2025 - MLB Spring Training
Mar 13, 2025 - MLB Spring Training
Mar 7, 2025 - MLB Spring Training
Mar 5, 2025 - MLB Spring Training
Feb 28, 2025 - MLB Spring Training
Feb 23, 2025 - MLB Spring Training
Houston Astros - St. Louis Cardinals Key Points
- The total has gone UNDER in 4 of St. Louis' last 5 games.
- The total has gone OVER in 4 of St. Louis' last 5 games against Houston.
- The total has gone UNDER in 10 of Houston's last 15 games on the road.
- The total has gone UNDER in 9 of Houston's last 13 games played on a Monday.
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Our Houston Astros vs St. Louis Cardinals Prediction
Astros’ ace Framber Valdez is listed to start on Monday vs. the Cardinals. Valdez looks to deliver a strong follow-up to his dominant showing against the Mariners after blanking Seattle for six innings with 8 strikeouts. Cardinals projected starter Sonny Gray will also try to put up strong numbers from the mound and continue to lead the Cardinals to a win like he did in his last three starts. A low-scoring Game 1 appears highly likely since we’ve got two solid pitchers going head-to-head. The total has gone UNDER in 10 of Houston's last 15 games on the road and 4 of St. Louis' last 5 games. Our betting prediction for the Houston Astros vs. St. Louis Cardinals: Total Under 7.0 Runs.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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