Houston Astros vs Los Angeles Angels Prediction & Picks - MLB

USA - MLB

Houston Astros
6/22/25 16:07
Los Angeles Angels

Prediction:

 

Houston ML

-110
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 by Travis Pulver in MLB Picks

The Los Angeles Angels will go for the series win over the Astros when they host Houston in Game 3 of their weekend series today. The action is scheduled to get underway at Angel Stadium in Anaheim, CA, at 4:07 p.m. EST.

Houston edged out the Angels in Game 1 of the series on Friday, 3-2, but Los Angeles came back with a vengeance in Game 2 with a 9-1 victory in Game 2 yesterday. Jose Soriano held the Astros lineup to three hits and a run over 6 2/3 innings. Houston’s starter Brandon Walter had pitched well over his first three starts (1.53 ERA), but got lit up by the Angels, nine hits (two home runs) and seven runs over six innings. The Astros will try to get back on the right side of the scoreboard with Ryan Gusto on the mound to start the day. Gusto is 4-3 in ten starts and 16 appearances this season with a 4.31 ERA and 1.53 WHIP. But he has been much better on the road, though, where he is 1-1 in two starts and six appearances with a 2.40 ERA. 

Kyle Hendricks is getting the start for the Angels. Hendricks has a 5-6 record in 14 starts with a 4.79 ERA. He has gone 3-3 at home in six starts with a 4.04 ERA and .265 OBA.

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Houston Astros vs Los Angeles Angels Form

Table

Teams % P W L
6
Houston Astros
Houston Astros
0.577 78 45 33
19
Los Angeles Angels
Los Angeles Angels
0.487 78 38 40

Houston Astros and Los Angeles Angels Latest Matches

Houston Astros
Houston Astros Latest matches
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 21, 2025 - MLB

Houston Astros
1 :  9
Los Angeles Angels

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Jun 19, 2025 - MLB

Houston Astros
4 :  6
Athletics

Jun 18, 2025 - MLB

Houston Astros
11 :  4
Athletics

Jun 17, 2025 - MLB

Houston Astros
13 :  3
Athletics

Jun 16, 2025 - MLB

Houston Astros
1 :  3
Athletics
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jun 15, 2025 - MLB

Minnesota Twins
1 :  2
Houston Astros

Jun 14, 2025 - MLB

Minnesota Twins
2 :  3
Houston Astros

Jun 13, 2025 - MLB

Minnesota Twins
3 :  10
Houston Astros

Jun 12, 2025 - MLB

Chicago White Sox
3 :  4
Houston Astros

Jun 11, 2025 - MLB

Chicago White Sox
2 :  10
Houston Astros

Jun 10, 2025 - MLB

Chicago White Sox
4 :  2
Houston Astros
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 21, 2025 - MLB

Houston Astros
1 :  9
Los Angeles Angels

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Jun 19, 2025 - MLB

Houston Astros
4 :  6
Athletics

Jun 18, 2025 - MLB

Houston Astros
11 :  4
Athletics

Jun 17, 2025 - MLB

Houston Astros
13 :  3
Athletics

Jun 16, 2025 - MLB

Houston Astros
1 :  3
Athletics
Los Angeles Angels
Los Angeles Angels Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 21, 2025 - MLB

Houston Astros
1 :  9
Los Angeles Angels

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Jun 19, 2025 - MLB

Los Angeles Angels
3 :  7
New York Yankees

Jun 18, 2025 - MLB

Los Angeles Angels
3 :  2
New York Yankees

Jun 17, 2025 - MLB

Los Angeles Angels
4 :  0
New York Yankees

Jun 16, 2025 - MLB

Los Angeles Angels
1 :  0
New York Yankees
W W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 21, 2025 - MLB

Houston Astros
1 :  9
Los Angeles Angels

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Jun 11, 2025 - MLB

Athletics
5 :  6
Los Angeles Angels

Jun 10, 2025 - MLB

Athletics
1 :  2
Los Angeles Angels

Jun 9, 2025 - MLB

Athletics
4 :  7
Los Angeles Angels

Jun 8, 2025 - MLB

Seattle Mariners
3 :  2
Los Angeles Angels
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 19, 2025 - MLB

Los Angeles Angels
3 :  7
New York Yankees

Jun 18, 2025 - MLB

Los Angeles Angels
3 :  2
New York Yankees

Jun 17, 2025 - MLB

Los Angeles Angels
4 :  0
New York Yankees

Jun 16, 2025 - MLB

Los Angeles Angels
1 :  0
New York Yankees

Jun 15, 2025 - MLB

Los Angeles Angels
2 :  11
Baltimore Orioles

Jun 14, 2025 - MLB

Los Angeles Angels
5 :  6
Baltimore Orioles

Houston Astros against Los Angeles Angels : Head to Head (H2H)

Houston Astros

50 %

Los Angeles Angels

50 %

Jun 21, 2025 - MLB

Houston Astros
1 :  9
Los Angeles Angels

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Apr 13, 2025 - MLB

Los Angeles Angels
3 :  7
Houston Astros

Apr 12, 2025 - MLB

Los Angeles Angels
4 :  1
Houston Astros

Apr 11, 2025 - MLB

Los Angeles Angels
3 :  14
Houston Astros

Sep 22, 2024 - MLB

Los Angeles Angels
9 :  8
Houston Astros

Houston Astros - Los Angeles Angels Key Points

  1. Houston leads the all-time series vs. the Angels 133-85.
  2. The Astros won nine of 12 against the Angels in Anaheim over the last two seasons.
  3. Houston is 11-12 in games where they were favored on the road.
  4. Betting Public: 62% of moneyline tickets and 70% of the handle are on Houston.
Up to $250 to bet on Houston Astros - Los Angeles Angels! 

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Our Houston Astros vs Los Angeles Angels Prediction

My first thought after looking at how both lineups have been hitting and how the starting pitchers have performed is to go with the OVER. But on closer examination, I see that while Gusto has been unimpressive at home, he has been solid on the road (2.40 ERA, .237 OBA), and he’s been even better in day games (1.59 ERA, .217 OBA). It is hard to trust how much support the lineup will provide, making the runline an unadvisable bet, but Gusto and the Astros' bullpen can win this game outright.

Our Astros vs. Angels Pick: Houston ML

Prediction:

 

Houston ML

-110
$250 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Houston Astros vs Los Angeles Angels Picks
Up to $250 to bet on Houston Astros - Los Angeles Angels! 

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