Houston Astros vs Los Angeles Angels Prediction & Picks - MLB

USA - MLB

Houston Astros
6/21/25 21:38
Los Angeles Angels

Prediction:

 

Houston Astros wins the match

+108
$200 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Carlos Zabala | in MLB Picks

Once again, just as happened in Houston earlier this season, the Angels were having a good run that was abruptly cut short by the Astros. The Astros won Game 1 of the series 2-3 in Los Angeles. Manager Espada will be happy to have trusted so much in Hunter Brown, who is in the midst of an elite season and was able to pitch another five innings against the Angels, allowing only one run. However, the game was close, and Espada had to rely on several bullpen players: Dubin, King, Abreu, Hader, and Sousa all combined to pitch five more innings and win in extra innings.

While the Astros have been the best team in MLB since late May, the Angels had to deal with some bad news: their 72-year-old manager, Ron Washington, will no longer be able to manage the team due to health issues.

For Game 2 at Angel Stadium, the pitching duel is scheduled between Walter, of the Astros, and Jose Soriano, of the Angels.

Houston Astros vs Los Angeles Angels Form

Table

Teams % P W L
7
Houston Astros
Houston Astros
0.577 78 45 33
21
Los Angeles Angels
Los Angeles Angels
0.481 77 37 40

Houston Astros and Los Angeles Angels Latest Matches

Houston Astros
Houston Astros Latest matches
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Jun 19, 2025 - MLB

Houston Astros
4 :  6
Athletics

Jun 18, 2025 - MLB

Houston Astros
11 :  4
Athletics

Jun 17, 2025 - MLB

Houston Astros
13 :  3
Athletics

Jun 16, 2025 - MLB

Houston Astros
1 :  3
Athletics

Jun 15, 2025 - MLB

Minnesota Twins
1 :  2
Houston Astros
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jun 15, 2025 - MLB

Minnesota Twins
1 :  2
Houston Astros

Jun 14, 2025 - MLB

Minnesota Twins
2 :  3
Houston Astros

Jun 13, 2025 - MLB

Minnesota Twins
3 :  10
Houston Astros

Jun 12, 2025 - MLB

Chicago White Sox
3 :  4
Houston Astros

Jun 11, 2025 - MLB

Chicago White Sox
2 :  10
Houston Astros

Jun 10, 2025 - MLB

Chicago White Sox
4 :  2
Houston Astros
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Jun 19, 2025 - MLB

Houston Astros
4 :  6
Athletics

Jun 18, 2025 - MLB

Houston Astros
11 :  4
Athletics

Jun 17, 2025 - MLB

Houston Astros
13 :  3
Athletics

Jun 16, 2025 - MLB

Houston Astros
1 :  3
Athletics

Jun 8, 2025 - MLB

Houston Astros
2 :  4
Cleveland Guardians
Los Angeles Angels
Los Angeles Angels Latest matches
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Jun 19, 2025 - MLB

Los Angeles Angels
3 :  7
New York Yankees

Jun 18, 2025 - MLB

Los Angeles Angels
3 :  2
New York Yankees

Jun 17, 2025 - MLB

Los Angeles Angels
4 :  0
New York Yankees

Jun 16, 2025 - MLB

Los Angeles Angels
1 :  0
New York Yankees

Jun 15, 2025 - MLB

Los Angeles Angels
2 :  11
Baltimore Orioles
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Jun 11, 2025 - MLB

Athletics
5 :  6
Los Angeles Angels

Jun 10, 2025 - MLB

Athletics
1 :  2
Los Angeles Angels

Jun 9, 2025 - MLB

Athletics
4 :  7
Los Angeles Angels

Jun 8, 2025 - MLB

Seattle Mariners
3 :  2
Los Angeles Angels

Jun 7, 2025 - MLB

Seattle Mariners
6 :  8
Los Angeles Angels
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 19, 2025 - MLB

Los Angeles Angels
3 :  7
New York Yankees

Jun 18, 2025 - MLB

Los Angeles Angels
3 :  2
New York Yankees

Jun 17, 2025 - MLB

Los Angeles Angels
4 :  0
New York Yankees

Jun 16, 2025 - MLB

Los Angeles Angels
1 :  0
New York Yankees

Jun 15, 2025 - MLB

Los Angeles Angels
2 :  11
Baltimore Orioles

Jun 14, 2025 - MLB

Los Angeles Angels
5 :  6
Baltimore Orioles

Houston Astros against Los Angeles Angels : Head to Head (H2H)

Houston Astros

67 %

Los Angeles Angels

33 %

Jun 20, 2025 - MLB

Houston Astros
3 :  2
Los Angeles Angels

Apr 13, 2025 - MLB

Los Angeles Angels
3 :  7
Houston Astros

Apr 12, 2025 - MLB

Los Angeles Angels
4 :  1
Houston Astros

Apr 11, 2025 - MLB

Los Angeles Angels
3 :  14
Houston Astros

Sep 22, 2024 - MLB

Los Angeles Angels
9 :  8
Houston Astros

Sep 20, 2024 - MLB

Los Angeles Angels
7 :  9
Houston Astros

Houston Astros - Los Angeles Angels Key Points

  1. Alvarez out due to injury for the Astros, Moncada and Soler out for the Angels
  2. Astros' pitching has the second-fewest runs allowed in average at 3.6
  3. Astros' pitching has the best K/9 in MLB at 9.99
  4. Astros' record is 8-2 in the last 10 games

Our Houston Astros vs Los Angeles Angels Prediction

Brandon Walter was a risky bet for the Astros. Walter was part of the Red Sox bullpen in 2023, missed 2024 due to surgery, but the Astros brought him in to start some games in 2025, and the gamble has paid off. He pitched 6 innings allowing 2 runs against the Guardians on June 8, and on June 15 he pitched another quality outing against the Twins, this time striking out 9. Our prediction for Angels vs Astros is: Astros ML.

Prediction:

 

Houston Astros wins the match

+108
$200 offered for betting!

Grab an extra $200 for your Houston Astros vs Los Angeles Angels wager!

Bet $5, Get $200

Get ready to experience the thrill of the game with FanDuel's exciting welcome offer, available for use on the Houston Astros vs Los Angeles Angels matchup!

A minimum bet of $5 will qualify for $200 in bonus bets if your bet wins! This offer is a golden opportunity for new users. Don't miss out on this limited-time deal to enhance your sports betting experience with some extra oomph! Jump into the action today and let FanDuel take your sports engagement to the next level!

$200 available for Houston Astros vs Los Angeles Angels

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Houston Astros vs Los Angeles Angels Picks