Houston Astros vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Houston Astros
6/6/25 19:10
Cleveland Guardians

Prediction:

 

The Astros -1.5 Runs

+155
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 by Lou Aguila in MLB Picks

The Houston Astros eye their fourth win in five games in Friday’s Game 1 of their new series against the Cleveland Guardians at Progressive Field.

The Astros (32-29) have won 3 of their last 4 games to overtake the 32-29 Seattle Mariners for the top spot in the AL West standings. Houston has displayed their elite pitching this week, scoring two shutout wins and a resounding 8-2 win over the Pirates in the finale of that series. Houston still sports a respectable 4.30 ERA over their last 5 games despite giving away 16 runs against Tampa Bay earlier this week.

The Guardians (33-28) are 2-3 in their last 5 games, but absorbing two losses in their three-game series with the Yankees left a bad taste in the mouth for this Cleveland team that still has World Series aspirations. Cleveland has dominated their opponents from the mound this week, parading an outstanding 2.51 ERA over their last five games. Unfortunately, Cleveland learned the hard way that scoring barely 4 runs a game would not be sufficient to outgun a high-powered Yankees team.

Houston Astros vs Cleveland Guardians Form

Table

Teams % P W L
9
Houston Astros
Houston Astros
0.548 62 34 28
12
Cleveland Guardians
Cleveland Guardians
0.541 61 33 28

Houston Astros and Cleveland Guardians Latest Matches

Houston Astros
Houston Astros Latest matches
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 5, 2025 - MLB

Houston Astros
8 :  2
Pittsburgh Pirates

Jun 4, 2025 - MLB

Houston Astros
0 :  3
Pittsburgh Pirates

Jun 3, 2025 - MLB

Houston Astros
3 :  0
Pittsburgh Pirates

Jun 1, 2025 - MLB

Tampa Bay Rays
0 :  1
Houston Astros

May 31, 2025 - MLB

Tampa Bay Rays
16 :  3
Houston Astros

May 30, 2025 - MLB

Tampa Bay Rays
1 :  2
Houston Astros
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 1, 2025 - MLB

Tampa Bay Rays
0 :  1
Houston Astros

May 31, 2025 - MLB

Tampa Bay Rays
16 :  3
Houston Astros

May 30, 2025 - MLB

Tampa Bay Rays
1 :  2
Houston Astros

May 29, 2025 - MLB

Tampa Bay Rays
13 :  3
Houston Astros

May 28, 2025 - MLB

Athletics
3 :  5
Houston Astros

May 27, 2025 - MLB

Athletics
1 :  11
Houston Astros
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 5, 2025 - MLB

Houston Astros
8 :  2
Pittsburgh Pirates

Jun 4, 2025 - MLB

Houston Astros
0 :  3
Pittsburgh Pirates

Jun 3, 2025 - MLB

Houston Astros
3 :  0
Pittsburgh Pirates

May 21, 2025 - MLB

Houston Astros
4 :  8
Tampa Bay Rays

May 20, 2025 - MLB

Houston Astros
2 :  3
Tampa Bay Rays

May 19, 2025 - MLB

Houston Astros
4 :  3
Tampa Bay Rays
Cleveland Guardians
Cleveland Guardians Latest matches
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 5, 2025 - MLB

Cleveland Guardians
0 :  4
New York Yankees

Jun 4, 2025 - MLB

Cleveland Guardians
4 :  0
New York Yankees

Jun 3, 2025 - MLB

Cleveland Guardians
2 :  3
New York Yankees

Jun 1, 2025 - MLB

Los Angeles Angels
2 :  4
Cleveland Guardians

May 31, 2025 - MLB

Los Angeles Angels
5 :  7
Cleveland Guardians

May 30, 2025 - MLB

Los Angeles Angels
4 :  1
Cleveland Guardians
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 1, 2025 - MLB

Los Angeles Angels
2 :  4
Cleveland Guardians

May 31, 2025 - MLB

Los Angeles Angels
5 :  7
Cleveland Guardians

May 30, 2025 - MLB

Los Angeles Angels
4 :  1
Cleveland Guardians

May 28, 2025 - MLB

Los Angeles Dodgers
4 :  7
Cleveland Guardians

May 27, 2025 - MLB

Los Angeles Dodgers
9 :  5
Cleveland Guardians

May 26, 2025 - MLB

Los Angeles Dodgers
7 :  2
Cleveland Guardians
W W L L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 5, 2025 - MLB

Cleveland Guardians
0 :  4
New York Yankees

Jun 4, 2025 - MLB

Cleveland Guardians
4 :  0
New York Yankees

Jun 3, 2025 - MLB

Cleveland Guardians
2 :  3
New York Yankees

May 25, 2025 - MLB

Cleveland Guardians
0 :  5
Detroit Tigers

May 24, 2025 - MLB

Cleveland Guardians
7 :  5
Detroit Tigers

May 23, 2025 - MLB

Cleveland Guardians
3 :  1
Detroit Tigers

Houston Astros against Cleveland Guardians : Head to Head (H2H)

Houston Astros

100 %

Cleveland Guardians

0 %

Sep 28, 2024 - MLB

Houston Astros
4 :  3
Cleveland Guardians

Sep 27, 2024 - MLB

Houston Astros
5 :  2
Cleveland Guardians

May 2, 2024 - MLB

Cleveland Guardians
2 :  8
Houston Astros

Apr 30, 2024 - MLB

Cleveland Guardians
9 :  10
Houston Astros

Jul 31, 2023 - MLB

Cleveland Guardians
3 :  7
Houston Astros

May 24, 2022 - MLB

Cleveland Guardians
3 :  7
Houston Astros

Houston Astros - Cleveland Guardians Key Points

  1. Houston is 7-1 SU in its last 8 games against Cleveland.
  2. Houston is 8-3 SU in its last 11 games.
  3. Cleveland is 12-5 SU in its last 17 games against an opponent in the American League.
  4. Cleveland is 3-6 SU in its last 9 games played in June.

Our Houston Astros vs Cleveland Guardians Prediction

Why you should bet on the Astros to cover -1.5 Runs (Win $155 on a $100 Bet): The Astros are 8-2 in their last 10 meetings vs. the Guardians. Houston also covered the -1.5-run spread in 5 of those 8 wins. The Astros have won in 3 of Colton Gordon’s 4 starts. Brown carries a 3-1 record with a 5.95 ERA in his rookie season. Guardians’ starter Logan Allen (2-3, 4.43 ERA in the last 5 starts) surrendered 4 earned runs in his last mound appearance and 5 earned runs the last time he pitched against the Astros.

Our betting prediction for the Houston Astros vs. the Cleveland Guardians: the Astros -1.5 Runs

Prediction:

 

The Astros -1.5 Runs

+155
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Houston Astros vs Cleveland Guardians Picks