Holger Rune vs Francisco Cerundolo Prediction & Picks - Laver Cup,Singles Matches

Prediction published on 9/20/25, 2:29 PM  by Lou Aguila | Modified on 9/20/25 at 10:55 PM in Tennis Picks

Holger Rune of Team Europe tussles with Francisco Cerundolo of Team World in the second singles match on Day 2 of the 2025 Laver Cup at Chase Center in San Francisco, California.

The former top-10 Rune is listed as a -275 favorite over Cerundolo, who has 14 top-10 wins in his career.

Current Form:

Rune is coming off an underwhelming campaign at the US Open, reaching only the second round after he got caught off guard by an upset-minded Jan-Lennard Struff 7-6(5) 2-6 6-3 4-6 7-5. Rune also represented Denmark at the Davis Cup’s tie with Spain, where he split his two men’s singles assignments. He won his first match against Pablo Carreno-Busta 7-5 6-3, but dropped a crucial loss to Pedro Martinez Portero 6-1 4-6 7-6(3) in rubber 4. The Dane is 15-8 on the hard court in 2025.

Cerundolo also participated in the Davis Cup, winning his singles match against Botic Van De Zandschulp of the Netherlands 7-6, 6-1 to help Argentina win the tie and advance to the quarterfinals. Cerundolo, a career 53 percent winner on the hard court, only reached the second round of the 2025 US Open after getting upset by Leandro Riedi 3-6 4-6 6-4 6-4 6-2 in the second round.