Hoffenheim vs Lyon Prediction & Picks - Europa League

Europe - Europa League

Hoffenheim
10/22/26 15:00
Lyon

Prediction:

 

BTTS & Over 2.5 Goals

−145
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 by Sarah Lou Jones | in Europa League Picks

Hoffenheim are looking for their first Europa League points of the season but they could find it tough as they welcome Lyon to the SNP Arena. The German side have lost both of their opening games of their European campaign, going down 2-0 away at OFI before losing at home 3-2 to Besiktas. Die Kraichgauer have lost four of their last six matches, though they do enter this match on the back of a 2-1 away win at Mönchengladbach in the Bundesliga. Lyon are looking for a third straight win in the competition, after beating Anderlecht and Crystal Palace.

Les Gones head into this one in good form. They've won four of their last six in all competitions. In Ligue Un, they've only lost one match and sit top of the French top tier. 

The last three meetings between these two sides have all ended in score draws. While we think Lyon will edge this game, we do think it will feature plenty of goals. For our prediction, we're looking at the Both Teams To Score/Over 2.5 Goals combo market.

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Hoffenheim vs Lyon Form

Table

Teams Pts P W D L GD
8 Lyon
6 2 2 0 0 +2
30 Hoffenheim
0 2 0 0 2 -3

Hoffenheim and Lyon Latest Matches

Hoffenheim
Hoffenheim Latest matches
W L L L L W
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Average stats (Last 6 matchs)

3.67 Total goals
83% BTTS
1.5 Goals scored
2.17 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 18, 2026 - Bundesliga

Mönchengladbach
1 :  2
Hoffenheim

Oct 15, 2026 - Europa League

Hoffenheim
2 :  3
Besiktas Istanbul

Oct 10, 2026 - Bundesliga

Hoffenheim
2 :  3
Hamburg

Sep 20, 2026 - Bundesliga

Paderborn
3 :  1
Hoffenheim

Sep 17, 2026 - Europa League

OFI Crete
2 :  0
Hoffenheim

Sep 12, 2026 - Bundesliga

Hoffenheim
2 :  1
Stuttgart
W L L W L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Average stats (Last 6 matchs)

4.33 Total goals
83% BTTS
2 Goals scored
2.33 Goals conceded
100% Over 2.5
0% Under 2.5

Oct 15, 2026 - Europa League

Hoffenheim
2 :  3
Besiktas Istanbul

Oct 10, 2026 - Bundesliga

Hoffenheim
2 :  3
Hamburg

Sep 12, 2026 - Bundesliga

Hoffenheim
2 :  1
Stuttgart

Sep 5, 2026 - Bundesliga

Hoffenheim
2 :  3
Borussia Dortmund

Aug 7, 2026 - Clubs Friendlies

Hoffenheim
1 :  4
Mönchengladbach

Aug 1, 2026 - Clubs Friendlies

Hoffenheim
3 :  0
Karlsruher
D W L L L W
Victories

2/6 (33%)

Draw

1/6 (17%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

3.67 Total goals
67% BTTS
1.83 Goals scored
1.83 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 18, 2026 - Bundesliga

Mönchengladbach
1 :  2
Hoffenheim

Sep 20, 2026 - Bundesliga

Paderborn
3 :  1
Hoffenheim

Sep 17, 2026 - Europa League

OFI Crete
2 :  0
Hoffenheim

Aug 29, 2026 - Bundesliga

Köln
3 :  2
Hoffenheim

Aug 22, 2026 - DFB Pokal

Erzgebirge Aue
0 :  4
Hoffenheim

Aug 16, 2026 - Clubs Friendlies

Tottenham
2 :  2
Hoffenheim
Lyon
Lyon Latest matches
D W W L W W
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3 Total goals
67% BTTS
2 Goals scored
1 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 18, 2026 - Ligue 1

Lyon
2 :  1
Nice

Oct 15, 2026 - Europa League

Lyon
3 :  2
Crystal Palace

Oct 9, 2026 - Ligue 1

Lens
2 :  1
Lyon

Sep 19, 2026 - Ligue 1

Lyon
4 :  0
Rennes

Sep 16, 2026 - Europa League

Anderlecht
1 :  2
Lyon

Sep 12, 2026 - Ligue 1

Paris FC
0 :  0
Lyon
L D W W W W
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3.5 Total goals
83% BTTS
2.33 Goals scored
1.17 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 18, 2026 - Ligue 1

Lyon
2 :  1
Nice

Oct 15, 2026 - Europa League

Lyon
3 :  2
Crystal Palace

Sep 19, 2026 - Ligue 1

Lyon
4 :  0
Rennes

Sep 4, 2026 - Ligue 1

Lyon
3 :  1
Auxerre

Aug 29, 2026 - Ligue 1

Lyon
1 :  1
Le Havre

Aug 26, 2026 - Champions League

Lyon
1 :  2
Fenerbahce Istanbul
L D W D W L
Victories

2/6 (33%)

Draw

2/6 (33%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

2.17 Total goals
67% BTTS
1.17 Goals scored
1 Goals conceded
50% Over 2.5
50% Under 2.5

Oct 9, 2026 - Ligue 1

Lens
2 :  1
Lyon

Sep 16, 2026 - Europa League

Anderlecht
1 :  2
Lyon

Sep 12, 2026 - Ligue 1

Paris FC
0 :  0
Lyon

Aug 22, 2026 - Ligue 1

Toulouse
0 :  2
Lyon

Aug 18, 2026 - Champions League

Fenerbahce Istanbul
1 :  1
Lyon

Aug 4, 2026 - Champions League

Sparta Prague
2 :  1
Lyon

Hoffenheim against Lyon : Head to Head (H2H)

Hoffenheim

0 %

Draw

100 %

Lyon

0 %

Average stats (last H2H results)

4.67
Total goals
100%
BTTS
2.33
Goals scored
2.33
Goals conceded
100%
Over 2.5
0%
Under 2.5

Nov 7, 2024 - Europa League

Hoffenheim
2 :  2
Lyon

Nov 7, 2018 - Champions League

Lyon
2 :  2
Hoffenheim

Oct 23, 2018 - Champions League

Hoffenheim
3 :  3
Lyon
Hoffenheim vs Lyon Picks

Lyon v Hoffenheim last Lineups

Hoffenheim

Formation : 4 - 3 - 3

1
O. Baumann
34
V. Coufal
2
R. Hranac
28
K. Machida
39
M. Rots
20
B. Conte
7
L. Avdullahu
22
A. Prass
19
T. Lemperle
11
F. Asllani
10
A. Hlozek
10
P. Sulc
26
K. Boudache
99
N. Nartey
24
J. Duranville
6
T. Tessmann
2
M. Bidstrup
16
A. Vinicius
19
M. Niakhate
22
C. Mata
13
Z. Athekame
40
R. Descamps

Formation : 4 - 2 - 3 - 1

Lyon

Substitutes

Hoffenheim
Hoffenheim
Goalkeeper

L. Philipp

Defender

O. Kabak

V. Gendrey

Midfielder

C. Lenz

W. Burger

A. Daghim

V. Lassig

Forward

A. Kramaric

M. Moerstedt

Lyon
Lyon
Goalkeeper

D. Greif

Defender

R. Kluivert

F. Bacher

Midfielder

T. Morton

C. Tolisso

K. Nakamura

K. Merah

Forward

R. Himbert

E. Nuamah

Missing players

Hoffenheim
Hoffenheim
Defender

A. Hajdari

Forward

P. Wimmer

Lyon
Lyon
Defender

N. Tagliafico

M. Ouedraogo

Forward

L. Openda

Most goals and assists

CD Huachipato Hoffenheim
CD Huachipato Lyon
Top Goalscorer
Japan K. Machida (1 Goals) , 
Kosovo F. Asllani (1 Goals)
Top Goalscorer
Japan K. Nakamura (1 Goals) ,  Denmark N. Nartey (1 Goals) ,  Ghana E. Nuamah (1 Goals) ,  France C. Tolisso (1 Goals) ,  Czech Republic P. Sulc (1 Goals)
Best assists
Czech Republic V. Coufal (1 Assists)
Best assists
Japan K. Nakamura (2 Assists)

Hoffenheim and Lyon Stats in Europa League

Hoffenheim
Hoffenheim
Lyon
Lyon
0%
Wins
100%
100%
Losses
0%
0%
Draws
0%
3.5
Average goals per match
4
1
Goals scored per match
2.5
2.5
Goals conceded per match
1.5
50%
Under 2.5 goals
0%
50%
Over 2.5 goals
100%
0%
No goals conceded
0%
50%
Both score
100%

Hoffenheim - Lyon Key Points

  1. Lyon's last five matches have featured over 2.5 goals
  2. Both teams have scored in four of Lyon's last five
  3. There were over 2.5 goals scored in five of Hoffenheim's last six
  4. Both teams have found the net in five of Hoffenheim's last six
Up to $200 to bet on Hoffenheim - Lyon! 

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Our Hoffenheim vs Lyon Prediction

Despite Hoffenheim not being in the greatest form, they're still no strangers to scoring goals. They're also not strangers to conceding them, either. While Lyon are in much better form they too score plenty as well as concede. We're expecdting this game to provide goals for each side.

Our prediction for Hoffenheim vs Lyon is: BTTS & Over 2.5 Goals

Prediction:

 

BTTS & Over 2.5 Goals

−145
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.