Arizona Cardinals vs Green Bay Packers Prediction & Picks - NFL

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Arizona Cardinals
10/19/25 16:25
Green Bay Packers

Prediction:

 

Arizona +6.5

-105
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 by Bill Christy | in NFL Picks

The banged-up Arizona Cardinals (2-4) will play hosts to the Green Bay Packers (3-1-1) late Sunday afternoon. The Cardinals fell just short of defeating he Indianapolis Colts last week with Jacoby Brissett starting in place of the injured Kyler Murray who could be out once again this week. The job was tough when Marvin Harrison Jr went down with a concussion midway through the game. All this coming after they lost star running back James Conner earlier this year for the season. While the 2-4 record is not great, it should be noted that these 4 losses have come by a combined 9 points. It is not like the Cardinals are laying down, they are just losing close games. The Packers, on the other hand, have won all 3 of their games by a decided margin of 10.6 points. Josh Jacobs has been running with purpose all season and Jordan Love has shown signs of being back to an elite passer. Jacobs has been dealing with an illness this week so that is something to keep an eye on as this game comes closer to kickoff. The defense is ranked in the top 10 in points allowed on the season and Micah Parsons has been a welcomed addition accounting for 2.4 sacks already this year in a limited capacity early.

Arizona Cardinals vs Green Bay Packers Form

Table

Teams Pts P W L
13 Green Bay Packers
0.529 17 9 7
30 Arizona Cardinals
0.176 17 3 14

Arizona Cardinals and Green Bay Packers Latest Matches

Arizona Cardinals
Arizona Cardinals Latest matches
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Oct 12, 2025 - NFL

Indianapolis Colts
31 :  27
Arizona Cardinals

Oct 5, 2025 - NFL

Arizona Cardinals
21 :  22
Tennessee Titans

Sep 25, 2025 - NFL

Arizona Cardinals
20 :  23
Seattle Seahawks

Sep 21, 2025 - NFL

San Francisco 49ers
16 :  15
Arizona Cardinals

Sep 14, 2025 - NFL

Arizona Cardinals
27 :  22
Carolina Panthers

Sep 7, 2025 - NFL

New Orleans Saints
13 :  20
Arizona Cardinals
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Oct 5, 2025 - NFL

Arizona Cardinals
21 :  22
Tennessee Titans

Sep 25, 2025 - NFL

Arizona Cardinals
20 :  23
Seattle Seahawks

Sep 14, 2025 - NFL

Arizona Cardinals
27 :  22
Carolina Panthers

Jan 5, 2025 - NFL

Arizona Cardinals
47 :  24
San Francisco 49ers

Dec 15, 2024 - NFL

Arizona Cardinals
30 :  17
New England Patriots

Dec 8, 2024 - NFL

Arizona Cardinals
18 :  30
Seattle Seahawks
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Oct 12, 2025 - NFL

Indianapolis Colts
31 :  27
Arizona Cardinals

Sep 21, 2025 - NFL

San Francisco 49ers
16 :  15
Arizona Cardinals

Sep 7, 2025 - NFL

New Orleans Saints
13 :  20
Arizona Cardinals

Dec 28, 2024 - NFL

Los Angeles Rams
13 :  9
Arizona Cardinals

Dec 22, 2024 - NFL

Carolina Panthers
36 :  30
Arizona Cardinals

Dec 1, 2024 - NFL

Minnesota Vikings
23 :  22
Arizona Cardinals
Green Bay Packers
Green Bay Packers Latest matches
L W W L D W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Oct 12, 2025 - NFL

Green Bay Packers
27 :  18
Cincinnati Bengals

Sep 28, 2025 - NFL

Dallas Cowboys
40 :  40
Green Bay Packers

Sep 21, 2025 - NFL

Cleveland Browns
13 :  10
Green Bay Packers

Sep 11, 2025 - NFL

Green Bay Packers
27 :  18
Washington Commanders

Sep 7, 2025 - NFL

Green Bay Packers
27 :  13
Detroit Lions

Jan 12, 2025 - NFL

Philadelphia Eagles
22 :  10
Green Bay Packers
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Oct 12, 2025 - NFL

Green Bay Packers
27 :  18
Cincinnati Bengals

Sep 11, 2025 - NFL

Green Bay Packers
27 :  18
Washington Commanders

Sep 7, 2025 - NFL

Green Bay Packers
27 :  13
Detroit Lions

Jan 5, 2025 - NFL

Green Bay Packers
22 :  24
Chicago Bears

Dec 23, 2024 - NFL

Green Bay Packers
34 :  0
New Orleans Saints

Nov 28, 2024 - NFL

Green Bay Packers
30 :  17
Miami Dolphins
L W L L L D
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 28, 2025 - NFL

Dallas Cowboys
40 :  40
Green Bay Packers

Sep 21, 2025 - NFL

Cleveland Browns
13 :  10
Green Bay Packers

Jan 12, 2025 - NFL

Philadelphia Eagles
22 :  10
Green Bay Packers

Dec 29, 2024 - NFL

Minnesota Vikings
27 :  25
Green Bay Packers

Dec 15, 2024 - NFL

Seattle Seahawks
13 :  30
Green Bay Packers

Dec 5, 2024 - NFL

Detroit Lions
34 :  31
Green Bay Packers

Arizona Cardinals against Green Bay Packers : Head to Head (H2H)

Arizona Cardinals

0 %

Green Bay Packers

100 %

Oct 13, 2024 - NFL

Green Bay Packers
34 :  13
Arizona Cardinals

Arizona Cardinals - Green Bay Packers Key Points

  1. Arizona is 7-1 ATS in its last 8 games when playing as the underdog.
  2. Arizona is 5-1 ATS in its last 6 games played in week 7.
  3. Green Bay is 2-6 ATS in its last 8 games.
  4. Green Bay is 1-4 ATS in its last 5 games on the road.

Our Arizona Cardinals vs Green Bay Packers Prediction

While the Packers were able to put the Bengals away last week, the game was much closer than the final score indicates. They also tied with a Cowboys team that seemingly always finds a way to lose and their only loss of the season came to the lowly Browns. This Packer team seems to play to the level of their competition and the Cardinals find a way to keep these games close. That is why we are backing the home underdogs in this one.

Prediction:

 

Arizona +6.5

-105
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Arizona Cardinals vs Green Bay Packers Picks