Frances Tiafoe vs Holger Rune Prediction & Picks - ATP Cincinnati Open

ATP - ATP Cincinnati Open

ATP 14 USA
Frances Tiafoe
8/13/25 11:00
ATP 9 Denmark
Holger Rune

Prediction:

 

Frances Tiafoe will win

+110
$250 offered for betting!

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 by Lou Aguila in ATP Cincinnati Open Picks

Can Frances Tiafoe stage another deep run in Cincinnati?

Frances Tiafoe of the United States opened as a +110 moneyline underdog ahead of his fourth-round matchup with Holger Rune of Denmark at the 2025 Cincinnati Open.

After getting modest results in Washington (quarterfinals) and Toronto (fourth round), Tiafoe is aiming for a better campaign at Cincinnati, where he was a finalist a year ago. So far, Tiafoe is looking like a real contender, dispatching Roberto Carballes Baena 6-4 6-3 and Ugo Humbert 6-4 6-4 in straight sets. Tiafoe is 11-7 on the hard court in 2025 and carries a 59 percent win rate on the surface in his career.

Rune powered past Alex Michelsen of the United States 7-6, 6-3 to reach the round of 16. The Dane conceded only one service break after capturing 80 percent of his first serves and drilling 9 aces. He also broke Michelsen twice by winning 22 return points. Ranked No.7 in the world, Rune is 14-7 on the hard court this year.

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Frances Tiafoe vs Holger Rune Form

Frances Tiafoe and Holger Rune Latest Matches

Frances Tiafoe Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 11, 2025 - ATP Cincinnati Open

Frances Tiafoe
2 :  0
Ugo Humbert

Aug 9, 2025 - ATP Cincinnati Open

Frances Tiafoe
2 :  0
Roberto Carballes Baena

Aug 3, 2025 - ATP Toronto

Frances Tiafoe
1 :  2
Alex De Minaur

Aug 1, 2025 - ATP Toronto

Frances Tiafoe
2 :  1
Aleksandar Vukic

Jul 30, 2025 - ATP Toronto

Frances Tiafoe
2 :  1
Yosuke Watanuki

Jul 25, 2025 - ATP Washington Citi Open

Ben Shelton
2 :  0
Frances Tiafoe
Holger Rune Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 11, 2025 - ATP Cincinnati Open

Alex Michelsen
0 :  2
Holger Rune

Aug 9, 2025 - ATP Cincinnati Open

Roman Safiullin
0 :  2
Holger Rune

Aug 2, 2025 - ATP Toronto

Alexei Popyrin
2 :  1
Holger Rune

Jul 31, 2025 - ATP Toronto

Alexandre Muller
0 :  2
Holger Rune

Jul 29, 2025 - ATP Toronto

Giovanni Mpetshi Perricard
0 :  2
Holger Rune

Jun 30, 2025 - ATP Wimbledon Championships

Holger Rune
2 :  3
Nicolás Jarry

Frances Tiafoe against Holger Rune : Head to Head (H2H)

Aug 18, 2024 - ATP Cincinnati Open

Frances Tiafoe
2 :  1
Holger Rune
Compare Frances Tiafoe and Holger Rune with our comparison tool.

Frances Tiafoe - Holger Rune Key Points

  1. Frances Tiafoe defeated Ugo Humbert 6-4, 6-4 in the third round of the 2025 Cincinnati Open.
  2. Frances Tiafoe is 11-7 on the hard court in 2025.
  3. Holger Rune defeated Alex Michelsen 7-6, 6-3 in the third round of the 2025 Cincinnati Open.
  4. Holger Rune is 14-7 on the hard court in 2025.
Up to $250 to bet on Frances Tiafoe - Holger Rune! 

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Our Frances Tiafoe vs Holger Rune Prediction

My money is on Frances Tiafoe in this intriguing round-of-16 matchup with Holger Rune. A rematch of last year’s semifinals at the same tournament, Tiafoe edged the Dane 4-6, 6-1, 7-6 to arrange a championship match with Jannik Sinner.

Both players have yet to drop a set in this tourney, demonstrating their impeccable form heading into their high-stakes match. Rune has always been a tough opponent across all surfaces, but he becomes more dangerous when he gets into his zone.

However, Tiafoe comes as an enticing moneyline option at +110 because of his history of success in this event. He has also created and converted more breakpoint chances (9 of 29) than Rune, who has won 5 of 11 breakpoints. This might be a risky bet, but I am going all in on Tiafoe for a straight-up win.

Our betting prediction for Frances Tiafoe vs. Holger Rune: Frances Tiafoe will win.

Prediction:

 

Frances Tiafoe will win

+110
$250 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Frances Tiafoe vs Holger Rune Picks
Up to $250 to bet on Frances Tiafoe - Holger Rune! 

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