San Francisco 49ers vs Detroit Lions Prediction & Picks - NFL

USA - NFL

San Francisco 49ers
12/30/24 20:15
Detroit Lions

Prediction:

 

Detroit -3.5

-110
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 by Bill Christy | in NFL Picks

=14.0ptThe 2024-2025 season was not what the Niners were expecting. The injury bug hit them hard and they were unable to keep their heads above water as the season went on. At 6-9, they are no longer in the playoff hunt. They have lost 5 of their last 6 with their lone win coming over the lowly Chicago Bears. In their last 2 losses, the Niners have allowed an average of 154 yards per game on the ground. That will be an issue again Monday Night where they face the top team in the NFC. The Detroit Lions are without David Montgomery but have Jahmyr Gibbs, who many believe is the better running back going full tilt. The Lions have averaged over 150 yards per game on the ground over their last 3 wins. In their latest loss to the Bills, they were held under 100 yards on the ground. They will be focused on getting Gibbs going early which will open things up for their passing game that has been steady all season. On the year, the Lions are passing for an average of 260+ yards per game, which is good for 2nd overall in the league. A win here will keep the Lions hopes alive for the #1 seed in the NFC.

San Francisco 49ers vs Detroit Lions Form

Table

Teams Pts P W L
2 Detroit Lions
0.882 17 15 2
22 San Francisco 49ers
0.353 17 6 11

San Francisco 49ers and Detroit Lions Latest Matches

San Francisco 49ers
San Francisco 49ers Latest matches
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Dec 22, 2024 - NFL

Miami Dolphins
29 :  17
San Francisco 49ers

Dec 12, 2024 - NFL

San Francisco 49ers
6 :  12
Los Angeles Rams

Dec 8, 2024 - NFL

San Francisco 49ers
38 :  13
Chicago Bears

Dec 1, 2024 - NFL

Buffalo Bills
35 :  10
San Francisco 49ers

Nov 24, 2024 - NFL

Green Bay Packers
38 :  10
San Francisco 49ers

Nov 17, 2024 - NFL

San Francisco 49ers
17 :  20
Seattle Seahawks
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Dec 12, 2024 - NFL

San Francisco 49ers
6 :  12
Los Angeles Rams

Dec 8, 2024 - NFL

San Francisco 49ers
38 :  13
Chicago Bears

Nov 17, 2024 - NFL

San Francisco 49ers
17 :  20
Seattle Seahawks

Oct 27, 2024 - NFL

San Francisco 49ers
30 :  24
Dallas Cowboys

Oct 20, 2024 - NFL

San Francisco 49ers
18 :  28
Kansas City Chiefs

Oct 6, 2024 - NFL

San Francisco 49ers
23 :  24
Arizona Cardinals
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Dec 22, 2024 - NFL

Miami Dolphins
29 :  17
San Francisco 49ers

Dec 1, 2024 - NFL

Buffalo Bills
35 :  10
San Francisco 49ers

Nov 24, 2024 - NFL

Green Bay Packers
38 :  10
San Francisco 49ers

Nov 10, 2024 - NFL

Tampa Bay Buccaneers
20 :  23
San Francisco 49ers

Oct 10, 2024 - NFL

Seattle Seahawks
24 :  36
San Francisco 49ers

Sep 22, 2024 - NFL

Los Angeles Rams
27 :  24
San Francisco 49ers
Detroit Lions
Detroit Lions Latest matches
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Dec 22, 2024 - NFL

Chicago Bears
17 :  34
Detroit Lions

Dec 15, 2024 - NFL

Detroit Lions
42 :  48
Buffalo Bills

Dec 5, 2024 - NFL

Detroit Lions
34 :  31
Green Bay Packers

Nov 28, 2024 - NFL

Detroit Lions
23 :  20
Chicago Bears

Nov 24, 2024 - NFL

Indianapolis Colts
6 :  24
Detroit Lions

Nov 17, 2024 - NFL

Detroit Lions
52 :  6
Jacksonville Jaguars
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Dec 15, 2024 - NFL

Detroit Lions
42 :  48
Buffalo Bills

Dec 5, 2024 - NFL

Detroit Lions
34 :  31
Green Bay Packers

Nov 28, 2024 - NFL

Detroit Lions
23 :  20
Chicago Bears

Nov 17, 2024 - NFL

Detroit Lions
52 :  6
Jacksonville Jaguars

Oct 27, 2024 - NFL

Detroit Lions
52 :  14
Tennessee Titans

Sep 30, 2024 - NFL

Detroit Lions
42 :  29
Seattle Seahawks
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Dec 22, 2024 - NFL

Chicago Bears
17 :  34
Detroit Lions

Nov 24, 2024 - NFL

Indianapolis Colts
6 :  24
Detroit Lions

Nov 10, 2024 - NFL

Houston Texans
23 :  26
Detroit Lions

Nov 3, 2024 - NFL

Green Bay Packers
14 :  24
Detroit Lions

Oct 20, 2024 - NFL

Minnesota Vikings
29 :  31
Detroit Lions

Oct 13, 2024 - NFL

Dallas Cowboys
9 :  47
Detroit Lions

San Francisco 49ers against Detroit Lions : Head to Head (H2H)

San Francisco 49ers

100 %

Detroit Lions

0 %

Jan 28, 2024 - NFL

San Francisco 49ers
34 :  31
Detroit Lions

San Francisco 49ers - Detroit Lions Key Points

  1. Detroit is 12-5 ATS in their last 17 games.
  2. Detroit is 9-1 ATS in their last 10 games on the road.
  3. San Francisco is 1-6 ATS in their last 7 games.
  4. San Francisco is 1-4 ATS in their last 5 games against Detroit.

Our San Francisco 49ers vs Detroit Lions Prediction

=14.0ptThe Lions have their path clearly in front of them and they can control their own destiny. With a win here against the Niners, they will just need to defeat their division rivals, the Minnesota Vikings next week. If the Lions win both games, they will be the overall 1 seed in the NFC, with a loss, they drop to the 5th seed. With the Lions playing for so much here, we like them to dominate the Niners from start to finish on Monday Night.  

=14.0ptOur prediction for San Francisco 49ers vs Detroit Lions:=14.0pt Detroit -3.5

Prediction:

 

Detroit -3.5

-110
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

San Francisco 49ers vs Detroit Lions Picks