Deportivo Toluca FC vs Club Santos Laguna Prediction & Picks - Liga MX

Mexico - Liga MX

Deportivo Toluca FC
9/20/26 20:00
Club Santos Laguna

Prediction:

 

Toluca Win & Over 3.5 Goals

-105
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 by Edgar Jibran | in Liga MX Picks

The Liga MX schedule has been very kind to Toluca’s home games, and this Sunday night won’t be the exception as the team faces Santos Laguna at 06:00 pm CST. In this match, Santos has virtually no chance of securing a positive outcome at Nemesio Diez Stadium, as its attack is far from competitive against the league's top teams.

With this in mind, it won’t be surprising if Antonio Mohamed rotates his initial lineup given the context of the game, especially after his team played a tough midweek match against Puebla. Still, it’s almost certain Paulinho will get minutes, as he still looks far from his best form despite scoring against Atlas last weekend.

Meanwhile, Santos Laguna finally secured its first victory of the season after a 2-1 win over FC Juárez last week. Although this was positive, the team isn’t expected to shoot more than three times on target in this game, as its main priority should be to avoid conceding more than 3 goals. With that objective in mind, Renato Paiva should use his knowledge of Toluca, as he is a former Toluca head coach.

Deportivo Toluca FC vs Club Santos Laguna Form

Table

Teams Pts P W D L GD
1 Deportivo Toluca FC
19 8 6 1 1 +12
17 Club Santos Laguna
4 8 1 1 6 -7

Deportivo Toluca FC and Club Santos Laguna Latest Matches

Deportivo Toluca FC
Deportivo Toluca FC Latest matches
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

3 Total goals
17% BTTS
2.67 Goals scored
0.33 Goals conceded
33% Over 2.5
67% Under 2.5

Sep 15, 2026 - Liga MX

Puebla
0 :  1
Deportivo Toluca FC

Sep 12, 2026 - Liga MX

Deportivo Toluca FC
5 :  2
Atlas FC

Sep 6, 2026 - Leagues Cup

Deportivo Toluca FC
2 :  0
Monterrey

Sep 2, 2026 - Leagues Cup

Deportivo Toluca FC
2 :  0
Club Leon

Aug 30, 2026 - Liga MX

Deportivo Toluca FC
4 :  0
FC Juarez

Aug 26, 2026 - Leagues Cup

Deportivo Toluca FC
2 :  0
Austin FC
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

3.5 Total goals
33% BTTS
3 Goals scored
0.5 Goals conceded
50% Over 2.5
50% Under 2.5

Sep 12, 2026 - Liga MX

Deportivo Toluca FC
5 :  2
Atlas FC

Sep 6, 2026 - Leagues Cup

Deportivo Toluca FC
2 :  0
Monterrey

Sep 2, 2026 - Leagues Cup

Deportivo Toluca FC
2 :  0
Club Leon

Aug 30, 2026 - Liga MX

Deportivo Toluca FC
4 :  0
FC Juarez

Aug 26, 2026 - Leagues Cup

Deportivo Toluca FC
2 :  0
Austin FC

Aug 12, 2026 - Leagues Cup

Deportivo Toluca FC
3 :  1
FC Dallas
L L W D W W
Victories

3/6 (50%)

Draw

1/6 (17%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

1.83 Total goals
33% BTTS
1 Goals scored
0.83 Goals conceded
33% Over 2.5
67% Under 2.5

Sep 15, 2026 - Liga MX

Puebla
0 :  1
Deportivo Toluca FC

Aug 21, 2026 - Liga MX

Queretaro
1 :  2
Deportivo Toluca FC

Aug 15, 2026 - Liga MX

Atlante
0 :  0
Deportivo Toluca FC

Jul 18, 2026 - Liga MX

Chivas
0 :  2
Deportivo Toluca FC

May 10, 2026 - Liga MX

CF Pachuca
2 :  0
Deportivo Toluca FC

Apr 29, 2026 - Concachampions

Los Angeles FC
2 :  1
Deportivo Toluca FC
Club Santos Laguna
Club Santos Laguna Latest matches
W L L D L W
Victories

2/6 (33%)

Draw

1/6 (17%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

2 Total goals
33% BTTS
1 Goals scored
1 Goals conceded
33% Over 2.5
67% Under 2.5

Sep 13, 2026 - Liga MX

Club Santos Laguna
2 :  1
FC Juarez

Sep 6, 2026 - Liga MX

CF Cruz Azul
1 :  0
Club Santos Laguna

Aug 29, 2026 - Liga MX

Club Santos Laguna
0 :  0
Tigres UANL

Aug 22, 2026 - Liga MX

Puebla
3 :  2
Club Santos Laguna

Aug 16, 2026 - Liga MX

Club Santos Laguna
0 :  1
Chivas

Aug 13, 2026 - Leagues Cup

Philadelphia Union
0 :  2
Club Santos Laguna
W L L L D W
Victories

2/6 (33%)

Draw

1/6 (17%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

1.5 Total goals
17% BTTS
0.83 Goals scored
0.67 Goals conceded
33% Over 2.5
67% Under 2.5

Sep 13, 2026 - Liga MX

Club Santos Laguna
2 :  1
FC Juarez

Aug 29, 2026 - Liga MX

Club Santos Laguna
0 :  0
Tigres UANL

Aug 16, 2026 - Liga MX

Club Santos Laguna
0 :  1
Chivas

Jul 25, 2026 - Liga MX

Club Santos Laguna
0 :  1
Atlas FC

Jul 9, 2026 - Clubs Friendlies

Club Santos Laguna
0 :  1
America de Cali

Apr 26, 2026 - Liga MX

Club Santos Laguna
3 :  0
Monterrey
L L L W L L
Victories

1/6 (17%)

Draw

0/6 (0%)

Defeats

5/6 (83%)

Average stats (Last 6 matchs)

2.83 Total goals
33% BTTS
0.83 Goals scored
2 Goals conceded
50% Over 2.5
50% Under 2.5

Sep 6, 2026 - Liga MX

CF Cruz Azul
1 :  0
Club Santos Laguna

Aug 22, 2026 - Liga MX

Puebla
3 :  2
Club Santos Laguna

Aug 13, 2026 - Leagues Cup

Philadelphia Union
0 :  2
Club Santos Laguna

Aug 9, 2026 - Leagues Cup

Chicago Fire
3 :  1
Club Santos Laguna

Aug 6, 2026 - Leagues Cup

New York City
2 :  0
Club Santos Laguna

Aug 2, 2026 - Liga MX

CF America
3 :  0
Club Santos Laguna

Deportivo Toluca FC against Club Santos Laguna : Head to Head (H2H)

Deportivo Toluca FC

67 %

Draw

0 %

Club Santos Laguna

33 %

Average stats (last H2H results)

3.33
Total goals
66.67%
BTTS
1.83
Goals scored
1.5
Goals conceded
66.67%
Over 2.5
33.33%
Under 2.5

Jan 14, 2026 - Liga MX

Deportivo Toluca FC
3 :  1
Club Santos Laguna

Jul 16, 2025 - Liga MX

Club Santos Laguna
2 :  4
Deportivo Toluca FC

Apr 6, 2025 - Liga MX

Deportivo Toluca FC
2 :  1
Club Santos Laguna

Sep 22, 2024 - Liga MX

Club Santos Laguna
2 :  0
Deportivo Toluca FC

Feb 21, 2024 - Liga MX

Deportivo Toluca FC
1 :  0
Club Santos Laguna

Nov 5, 2023 - Liga MX

Club Santos Laguna
3 :  1
Deportivo Toluca FC
Deportivo Toluca FC vs Club Santos Laguna Picks

Club Santos Laguna v Deportivo Toluca FC last Lineups

Deportivo Toluca FC

Formation : 4 - 2 - 3 - 1

22
L. Garcia
2
D. Zaragoza
4
B. Mendez
6
F. Pereira
25
E. del Villar
5
F. Romero
20
J. Gallardo
16
F. Vinas
10
R. Angulo
8
N. Castro
26
Paulinho
19
E. Aguirre
10
E. Bullaude
77
K. Palacios
7
D. Gonzalez
21
F. Villalba
23
F. Caseres
3
M. Cuevas
14
E. Orona
25
F. Sanchez
18
F. Pardo
1
C. Acevedo

Formation : 3 - 4 - 3

Club Santos Laguna

Substitutes

Deportivo Toluca FC
Deportivo Toluca FC
Goalkeeper

R. Beltran

Defender

A. Briseno

Luan

Midfielder

V. Guzman

J. Diaz

S. Aceves

F. Arce

Forward

O. Virgen

Helinho

P. Perez

Club Santos Laguna
Club Santos Laguna
Goalkeeper

H. Holguin

Defender

E. Echeverria

J. Perez

J. Abella

Midfielder

L. Gomez

S. Mariscal

J. Guemez

Forward

T. Jimnez

E. Lozano

R. Sordo

Missing players

Deportivo Toluca FC
Deportivo Toluca FC
Midfielder

M. Ruiz

S. Simon

Club Santos Laguna
Club Santos Laguna
Defender

B. Amione

Forward

L. Di Yorio

Most goals and assists

CD Huachipato Deportivo Toluca FC
CD Huachipato Club Santos Laguna
Top Goalscorer
Uruguay F. Vinas (3 Goals)
Top Goalscorer
Argentina E. Bullaude (2 Goals)
Best assists
Brazil Helinho (2 Assists)
Best assists
Argentina F. Sanchez (1 Assists)
Spain F. Villalba (1 Assists)
Argentina E. Bullaude (1 Assists)
USA M. Cuevas (1 Assists)

Deportivo Toluca FC and Club Santos Laguna Stats in Liga MX

Deportivo Toluca FC
Deportivo Toluca FC
Club Santos Laguna
Club Santos Laguna
75%
Wins
13%
13%
Losses
75%
13%
Draws
13%
3
Average goals per match
2.38
2.25
Goals scored per match
0.75
0.75
Goals conceded per match
1.63
38%
Under 2.5 goals
50%
63%
Over 2.5 goals
50%
50%
No goals conceded
13%
50%
Both score
38%

Deportivo Toluca FC - Club Santos Laguna Key Points

  1. Toluca has a five-game home winning streak, during which it scored three or more goals per game.
  2. Santos Laguna lost a three-game road streak of scoring at least one goal per game, with its 1-0 loss to Cruz Azul.
  3. Toluca has a six-game winning streak in home meetings against Santos Laguna, and it scored two or more goals in five of those games.
  4. Santos Laguna has scored at least one goal in nine of its last ten road meetings against Toluca, a positive streak that will be difficult to overcome this time.

Our Deportivo Toluca FC vs Club Santos Laguna Prediction

Given these factors, even if Toluca faces this game with some rotations in the initial lineup, it is expected to deliver a dominant performance and extend its magnificent home winning streak. Additionally, given their well-known superiority over Santos, this team could play at a low pace in the first minutes of the game.

In conclusion, even though Renato Paiva was an essential part of Toluca’s restructure before Mohamed’s era, the crowd isn’t expected to welcome him properly due to his unforgivable failure at Nemesio Diez Stadium against Herediano. Therefore, the pick for Deportivo Toluca FC – Club Santos Laguna is: Toluca Win & Over 3.5 Goals!

Prediction:

 

Toluca Win & Over 3.5 Goals

-105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.