Tampa Bay Rays vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Tampa Bay Rays
10/12/26 20:00
Cleveland Guardians

Prediction:

 

Tampa Bay Rays to win

-164
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 by Stephen Abiola | in MLB Picks

Tampa Bay Rays will open the American League Championship Series with a home game against Cleveland Guardians on Monday night at Tropicana Field. The Rays are coming off a 4-3 win over the Yankees to complete a 3-game division series sweep and book a date with the Guardians. This will be the first time since 2020 that the Rays are reaching the ALCS, and they’ll be eager to start strongly at home. Tampa Bay Rays are the -175 betting favorites tonight.

Cleveland Guardians, meanwhile, needed a Game 5 win to knock out the White Sox and proceed to the ALCS. They dug themselves out of a 0-2 hole to take the final three games, including a 2-0 win on Saturday at Progressive Field. The Guardians produced an exemplary pitching performance, limiting the Sox to just a single scoring opportunity in the sixth. They’ll be keen to pull off an upset as the +130 betting underdogs tonight.

Tampa Bay Rays vs Cleveland Guardians Form

Tampa Bay Rays and Cleveland Guardians Latest Matches

Tampa Bay Rays
Tampa Bay Rays Latest matches
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Oct 7, 2026 - MLB

New York Yankees
3 :  4
Tampa Bay Rays

Oct 5, 2026 - MLB

Tampa Bay Rays
5 :  2
New York Yankees

Oct 3, 2026 - MLB

Tampa Bay Rays
1 :  0
New York Yankees

Sep 27, 2026 - MLB

Philadelphia Phillies
7 :  3
Tampa Bay Rays

Sep 26, 2026 - MLB

Philadelphia Phillies
1 :  12
Tampa Bay Rays

Sep 25, 2026 - MLB

Philadelphia Phillies
0 :  2
Tampa Bay Rays
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Oct 5, 2026 - MLB

Tampa Bay Rays
5 :  2
New York Yankees

Oct 3, 2026 - MLB

Tampa Bay Rays
1 :  0
New York Yankees

Sep 20, 2026 - MLB

Tampa Bay Rays
5 :  1
Boston Red Sox

Sep 19, 2026 - MLB

Tampa Bay Rays
2 :  1
Boston Red Sox

Sep 18, 2026 - MLB

Tampa Bay Rays
2 :  4
Boston Red Sox

Sep 17, 2026 - MLB

Tampa Bay Rays
10 :  1
Athletics
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Oct 7, 2026 - MLB

New York Yankees
3 :  4
Tampa Bay Rays

Sep 27, 2026 - MLB

Philadelphia Phillies
7 :  3
Tampa Bay Rays

Sep 26, 2026 - MLB

Philadelphia Phillies
1 :  12
Tampa Bay Rays

Sep 25, 2026 - MLB

Philadelphia Phillies
0 :  2
Tampa Bay Rays

Sep 24, 2026 - MLB

New York Yankees
6 :  4
Tampa Bay Rays

Sep 23, 2026 - MLB

New York Yankees
9 :  2
Tampa Bay Rays
Cleveland Guardians
Cleveland Guardians Latest matches
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Oct 10, 2026 - MLB

Cleveland Guardians
2 :  0
Chicago White Sox

Oct 8, 2026 - MLB

Chicago White Sox
5 :  9
Cleveland Guardians

Oct 7, 2026 - MLB

Chicago White Sox
3 :  9
Cleveland Guardians

Oct 5, 2026 - MLB

Cleveland Guardians
3 :  4
Chicago White Sox

Oct 3, 2026 - MLB

Cleveland Guardians
0 :  3
Chicago White Sox

Sep 27, 2026 - MLB

Kansas City Royals
3 :  2
Cleveland Guardians
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Oct 10, 2026 - MLB

Cleveland Guardians
2 :  0
Chicago White Sox

Oct 5, 2026 - MLB

Cleveland Guardians
3 :  4
Chicago White Sox

Oct 3, 2026 - MLB

Cleveland Guardians
0 :  3
Chicago White Sox

Sep 20, 2026 - MLB

Cleveland Guardians
1 :  0
Athletics

Sep 19, 2026 - MLB

Cleveland Guardians
12 :  6
Athletics

Sep 18, 2026 - MLB

Cleveland Guardians
5 :  3
Athletics
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Oct 8, 2026 - MLB

Chicago White Sox
5 :  9
Cleveland Guardians

Oct 7, 2026 - MLB

Chicago White Sox
3 :  9
Cleveland Guardians

Sep 27, 2026 - MLB

Kansas City Royals
3 :  2
Cleveland Guardians

Sep 26, 2026 - MLB

Kansas City Royals
5 :  11
Cleveland Guardians

Sep 25, 2026 - MLB

Kansas City Royals
9 :  12
Cleveland Guardians

Sep 24, 2026 - MLB

Boston Red Sox
0 :  1
Cleveland Guardians

Tampa Bay Rays against Cleveland Guardians : Head to Head (H2H)

Tampa Bay Rays

83 %

Cleveland Guardians

17 %

Jul 26, 2026 - MLB

Tampa Bay Rays
1 :  0
Cleveland Guardians

Jul 25, 2026 - MLB

Tampa Bay Rays
3 :  0
Cleveland Guardians

Jul 24, 2026 - MLB

Tampa Bay Rays
11 :  3
Cleveland Guardians

Apr 29, 2026 - MLB

Cleveland Guardians
3 :  1
Tampa Bay Rays

Apr 28, 2026 - MLB

Cleveland Guardians
0 :  1
Tampa Bay Rays

Apr 27, 2026 - MLB

Cleveland Guardians
2 :  3
Tampa Bay Rays
Tampa Bay Rays vs Cleveland Guardians Picks

Tampa Bay Rays - Cleveland Guardians Key Points

  1. Tampa Bay Rays are 10-1 in their last 11 home matches
  2. Tampa Bay Rays are 5-1 in their last six matches all-time.
  3. Tampa Bay Rays are 5-1 in their last six matches against the Guardians.
  4. Tampa Bay Rays won their last three home games against the Guardians.

Our Tampa Bay Rays vs Cleveland Guardians Prediction

Our money is on Tampa Bay Rays to win tonight. They’ve been the more consistent side this season, especially at home, where they finished the regular season with a 55-26 record. The Rays have already won their two home games during the playoffs. They’ll start Drew Rasmussen, who will be keen to build on his 16-5 record and 2.67 ERA this season. The right-hander can produce six or seven solid innings to help the Rays contain Cleveland’s explosive attacks. The visitors will start Foster Griffin, who finished the regular season with a 15-6 record and a 3.60 ERA. Overall, the Rays should have the advantage at home.

Our prediction for Tampa Bay Rays vs Cleveland Guardians: Tampa Bay Rays to win.

Prediction:

 

Tampa Bay Rays to win

-164
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.