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by Lou Aguila | in MLB Picks
The Detroit Tigers and the Cleveland Guardians kick off their 4-game weekend series on Thursday at Comerica Park.
The Tigers have won 3 of their last 4 games, including the final two matches of their series against the St. Louis Cardinals, to improve their regular-slate to 33-17, No.1 in the AL Central standings. Detroit is still churning out terrific numbers from the mound, pitching a 3.32 ERA and 1.16 WHIP this season.
The Guardians snapped a 5-game skid with a 5-1 win over the Minnesota Twins on Wednesday. Cleveland are fourth in the AL Central standings with a 26-22 record, 6 games behind the Tigers. Over their last five games, the Guardians are averaging 3.2 runs per game and a 3.89 ERA.
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Cleveland Guardians vs Detroit Tigers Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
1
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0.626 | 91 | 57 | 34 |
22
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0.455 | 88 | 40 | 48 |
Cleveland Guardians and Detroit Tigers Latest Matches

1/6 (17%)
5/6 (83%)
May 21, 2025 - MLB
May 19, 2025 - MLB
May 18, 2025 - MLB
May 17, 2025 - MLB
May 16, 2025 - MLB
May 14, 2025 - MLB
3/6 (50%)
3/6 (50%)
May 14, 2025 - MLB
May 13, 2025 - MLB
May 12, 2025 - MLB
May 11, 2025 - MLB
May 10, 2025 - MLB
May 9, 2025 - MLB
2/6 (33%)
4/6 (67%)
May 21, 2025 - MLB
May 19, 2025 - MLB
May 18, 2025 - MLB
May 17, 2025 - MLB
May 16, 2025 - MLB
May 7, 2025 - MLB

4/6 (67%)
2/6 (33%)
May 21, 2025 - MLB
May 20, 2025 - MLB
May 19, 2025 - MLB
May 18, 2025 - MLB
May 17, 2025 - MLB
May 16, 2025 - MLB
4/6 (67%)
2/6 (33%)
May 14, 2025 - MLB
May 13, 2025 - MLB
May 12, 2025 - MLB
May 11, 2025 - MLB
May 10, 2025 - MLB
May 9, 2025 - MLB
4/6 (67%)
2/6 (33%)
May 21, 2025 - MLB
May 20, 2025 - MLB
May 19, 2025 - MLB
May 18, 2025 - MLB
May 17, 2025 - MLB
May 16, 2025 - MLB
Cleveland Guardians against Detroit Tigers : Head to Head (H2H)
67 %
33 %
Oct 12, 2024 - MLB
Oct 10, 2024 - MLB
Oct 9, 2024 - MLB
Oct 7, 2024 - MLB
Oct 5, 2024 - MLB
Jul 30, 2024 - MLB
Cleveland Guardians - Detroit Tigers Key Points
- Detroit is 8-2 SU in its last 10 games against an opponent in the American League Central Division
- Detroit is 7-2 SU in its last 9 games.
- Cleveland is 1-4 SU in its last 5 games.
- Cleveland is 5-2 SU in its last 7 games against Detroit.
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Our Cleveland Guardians vs Detroit Tigers Prediction
Fearless Forecast: Tigers take first game of the series vs. the Guardians
Why we should bet on the Tigers to cover -1.5 runs: Apart from their 17-5 record at Comerica Park this season, the Tigers are sending in Guardians killer Jack Flaherty, who has allowed zero earned runs in his last two starts vs. Cleveland. The Tigers are batting 5.4 runs per game on a .259 batting average at home this season, which could be bad news for Guardians starter Tanner Bibee. Bibee allowed 4 earned runs in 4-5 loss to the Cincinnati Reds in his last start on May 16. Cleveland is 1-4 SU in its last 5 games, while Detroit is 8-2 SU in its last 10 games against an American League Central Division opponent.
Our betting prediction for the Detroit Tigers vs. the Cleveland Guardians: Tigers -1.5 runs
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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