Cleveland Guardians vs Detroit Tigers Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
5/22/25 18:40
Detroit Tigers

Prediction:

 

Tigers -1.5 Runs

+165
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 by Lou Aguila | in MLB Picks

The Detroit Tigers and the Cleveland Guardians kick off their 4-game weekend series on Thursday at Comerica Park.

The Tigers have won 3 of their last 4 games, including the final two matches of their series against the St. Louis Cardinals, to improve their regular-slate to 33-17, No.1 in the AL Central standings. Detroit is still churning out terrific numbers from the mound, pitching a 3.32 ERA and 1.16 WHIP this season.

The Guardians snapped a 5-game skid with a 5-1 win over the Minnesota Twins on Wednesday. Cleveland are fourth in the AL Central standings with a 26-22 record, 6 games behind the Tigers. Over their last five games, the Guardians are averaging 3.2 runs per game and a 3.89 ERA.

Cleveland Guardians vs Detroit Tigers Form

Table

Teams % P W L
1
Detroit Tigers
Detroit Tigers
0.626 91 57 34
22
Cleveland Guardians
Cleveland Guardians
0.455 88 40 48

Cleveland Guardians and Detroit Tigers Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 21, 2025 - MLB

Cleveland Guardians
5 :  1
Minnesota Twins

May 19, 2025 - MLB

Cleveland Guardians
5 :  6
Minnesota Twins

May 18, 2025 - MLB

Cleveland Guardians
1 :  3
Cincinnati Reds

May 17, 2025 - MLB

Cleveland Guardians
1 :  4
Cincinnati Reds

May 16, 2025 - MLB

Cleveland Guardians
4 :  5
Cincinnati Reds

May 14, 2025 - MLB

Milwaukee Brewers
9 :  5
Cleveland Guardians
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 14, 2025 - MLB

Milwaukee Brewers
9 :  5
Cleveland Guardians

May 13, 2025 - MLB

Milwaukee Brewers
0 :  2
Cleveland Guardians

May 12, 2025 - MLB

Milwaukee Brewers
0 :  5
Cleveland Guardians

May 11, 2025 - MLB

Philadelphia Phillies
3 :  0
Cleveland Guardians

May 10, 2025 - MLB

Philadelphia Phillies
7 :  1
Cleveland Guardians

May 9, 2025 - MLB

Philadelphia Phillies
0 :  6
Cleveland Guardians
W L L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 21, 2025 - MLB

Cleveland Guardians
5 :  1
Minnesota Twins

May 19, 2025 - MLB

Cleveland Guardians
5 :  6
Minnesota Twins

May 18, 2025 - MLB

Cleveland Guardians
1 :  3
Cincinnati Reds

May 17, 2025 - MLB

Cleveland Guardians
1 :  4
Cincinnati Reds

May 16, 2025 - MLB

Cleveland Guardians
4 :  5
Cincinnati Reds

May 7, 2025 - MLB

Cleveland Guardians
8 :  6
Washington Nationals
Detroit Tigers
Detroit Tigers Latest matches
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 21, 2025 - MLB

Detroit Tigers
5 :  1
St. Louis Cardinals

May 20, 2025 - MLB

Detroit Tigers
5 :  4
St. Louis Cardinals

May 19, 2025 - MLB

Detroit Tigers
4 :  11
St. Louis Cardinals

May 18, 2025 - MLB

Detroit Tigers
3 :  2
Toronto Blue Jays

May 17, 2025 - MLB

Detroit Tigers
1 :  2
Toronto Blue Jays

May 16, 2025 - MLB

Detroit Tigers
5 :  4
Toronto Blue Jays
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 14, 2025 - MLB

Boston Red Sox
5 :  6
Detroit Tigers

May 13, 2025 - MLB

Boston Red Sox
9 :  10
Detroit Tigers

May 12, 2025 - MLB

Boston Red Sox
2 :  14
Detroit Tigers

May 11, 2025 - MLB

Texas Rangers
6 :  1
Detroit Tigers

May 10, 2025 - MLB

Texas Rangers
10 :  3
Detroit Tigers

May 9, 2025 - MLB

Texas Rangers
1 :  2
Detroit Tigers
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 21, 2025 - MLB

Detroit Tigers
5 :  1
St. Louis Cardinals

May 20, 2025 - MLB

Detroit Tigers
5 :  4
St. Louis Cardinals

May 19, 2025 - MLB

Detroit Tigers
4 :  11
St. Louis Cardinals

May 18, 2025 - MLB

Detroit Tigers
3 :  2
Toronto Blue Jays

May 17, 2025 - MLB

Detroit Tigers
1 :  2
Toronto Blue Jays

May 16, 2025 - MLB

Detroit Tigers
5 :  4
Toronto Blue Jays

Cleveland Guardians against Detroit Tigers : Head to Head (H2H)

Cleveland Guardians

67 %

Detroit Tigers

33 %

Oct 12, 2024 - MLB

Detroit Tigers
3 :  7
Cleveland Guardians

Oct 10, 2024 - MLB

Cleveland Guardians
5 :  4
Detroit Tigers

Oct 9, 2024 - MLB

Cleveland Guardians
0 :  3
Detroit Tigers

Oct 7, 2024 - MLB

Detroit Tigers
3 :  0
Cleveland Guardians

Oct 5, 2024 - MLB

Detroit Tigers
0 :  7
Cleveland Guardians

Jul 30, 2024 - MLB

Cleveland Guardians
5 :  0
Detroit Tigers

Cleveland Guardians - Detroit Tigers Key Points

  1. Detroit is 8-2 SU in its last 10 games against an opponent in the American League Central Division
  2. Detroit is 7-2 SU in its last 9 games.
  3. Cleveland is 1-4 SU in its last 5 games.
  4. Cleveland is 5-2 SU in its last 7 games against Detroit.

Our Cleveland Guardians vs Detroit Tigers Prediction

Fearless Forecast: Tigers take first game of the series vs. the Guardians

Why we should bet on the Tigers to cover -1.5 runs: Apart from their 17-5 record at Comerica Park this season, the Tigers are sending in Guardians killer Jack Flaherty, who has allowed zero earned runs in his last two starts vs. Cleveland. The Tigers are batting 5.4 runs per game on a .259 batting average at home this season, which could be bad news for Guardians starter Tanner Bibee. Bibee allowed 4 earned runs in 4-5 loss to the Cincinnati Reds in his last start on May 16. Cleveland is 1-4 SU in its last 5 games, while Detroit is 8-2 SU in its last 10 games against an American League Central Division opponent.

Our betting prediction for the Detroit Tigers vs. the Cleveland Guardians: Tigers -1.5 runs

Prediction:

 

Tigers -1.5 Runs

+165
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Cleveland Guardians vs Detroit Tigers Picks