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by Stephen Abiola in MLB Picks
Arizona Diamondbacks (61-66) will look to continue their improvement this month when they take on Cleveland Guardians (64-61) on Wednesday evening. The Diamondbacks, who have averaged 5.4 runs per contest in August, will want to wrap up this three-game series with a win after recovering from a 3-1 loss in the first game to defeat the Guardians 6-5 on Tuesday night. The D-Backs are 5-5 in their previous 10 assignments, sitting fourth in the NL West.
The Guardians, meanwhile, are in dire need of a series win after being swept aside 3-0 by Atlanta in their previous assignment. Their 64-61 record is good for third in the AL Central division, and they are just 0.5 games behind the Royals in second place. However, the Royals are currently playing beautiful baseball, and the Guardians must improve quickly to pip them to the coveted second spot. They don’t have any new injuries ahead of the clash against the D-Backs.
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Cleveland Guardians vs Arizona Diamondbacks Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
15
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0.512 | 125 | 64 | 61 |
20
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0.48 | 127 | 61 | 66 |
Cleveland Guardians and Arizona Diamondbacks Latest Matches

2/6 (33%)
4/6 (67%)
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Aug 17, 2025 - MLB
Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
Aug 14, 2025 - MLB
2/6 (33%)
4/6 (67%)
Aug 17, 2025 - MLB
Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
Aug 14, 2025 - MLB
Aug 13, 2025 - MLB
Aug 12, 2025 - MLB
4/6 (67%)
2/6 (33%)
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Aug 10, 2025 - MLB
Aug 9, 2025 - MLB
Aug 8, 2025 - MLB
Aug 6, 2025 - MLB

2/6 (33%)
4/6 (67%)
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Aug 17, 2025 - MLB
Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
Aug 14, 2025 - MLB
4/6 (67%)
2/6 (33%)
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Aug 10, 2025 - MLB
Aug 9, 2025 - MLB
Aug 8, 2025 - MLB
Aug 6, 2025 - MLB
3/6 (50%)
3/6 (50%)
Aug 17, 2025 - MLB
Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
Aug 14, 2025 - MLB
Aug 13, 2025 - MLB
Aug 12, 2025 - MLB
Cleveland Guardians against Arizona Diamondbacks : Head to Head (H2H)
67 %
33 %
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Mar 25, 2025 - MLB Spring Training
Mar 24, 2025 - MLB Spring Training
Mar 6, 2025 - MLB Spring Training
Feb 24, 2025 - MLB Spring Training
Cleveland Guardians - Arizona Diamondbacks Key Points
- The Guardians are 4-11 in their last 15 matches against Arizona.
- The total runs went under in three of the last four Arizona vs Cleveland clashes.
- The total runs went under in four of the last six Arizona matches.
- The total went under in six of the last 10 Arizona matches at home.
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Our Cleveland Guardians vs Arizona Diamondbacks Prediction
Bookmakers anticipate a close game with the Diamondbacks being the slight -136 betting favorites. On paper, the Guardians are the in-form side, winning 12 of their last 18 matches all-time. They also boast an impressive record of 6-2 in their previous eight games on the road. However, their recent record has been wanting, scoring an average of 2.6 runs per game in the last five matches. While at it, their pitchers allowed an average of 5.6 runs per contest. This could be their weakest link against the Diamondbacks, who have an average of 4.4 runs in the last five fixtures. We wouldn’t want to bet on Cleveland to cover the +1 run line here.
Our prediction for Arizona Diamondbacks vs Cleveland Guardians: Under 9 runs.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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