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by Travis Pulver in MLB Picks
The Arizona Diamondbacks will host the Cincinnati Reds at Chase Field in Phoenix, AZ, this weekend. Game One of the series is scheduled for tonight at 9:40 p.m. EST. Cincinnati comes into the series having won three of their last four and a half game back of the Mets for the final NL wild card spot. Arizona lost the first game in their recent series vs. the Guardians, but pulled out wins in the final two games, both by a single run. They aren’t necessarily out of the playoff race, but they are 5.5 games back for the final wild card spot and don’t have much time to make up the difference.
Zack Littell is scheduled to get the start for Cincinnati. Littell has gone 9-8 in 25 starts with a 3.52 ERA, 1.11 WHIP, and .249 OBA. In 14 road starts, he’s gone 7-4 with a 3.76 ERA and .246 OBA. Since being acquired by the Reds from Tampa Bay, he’s gone 1-0 in three starts with a 3.06 ERA. As for the home team, the Diamondbacks will hand the ball to Ryne Nelson. Nelson has a 6-3 record in 16 starts (26 appearances) with a 3.58 ERA, 1.07 WHIP, and .215 OBA. He’s done his best work at home this season, going 5-1 with a save in 13 appearances (seven starts) with a 2.20 ERA and .207 OBA.
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Cincinnati Reds vs Arizona Diamondbacks Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
13
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0.515 | 130 | 67 | 63 |
17
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0.492 | 130 | 64 | 66 |
Cincinnati Reds and Arizona Diamondbacks Latest Matches

3/6 (50%)
3/6 (50%)
Aug 20, 2025 - MLB
Aug 19, 2025 - MLB
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Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
3/6 (50%)
3/6 (50%)
Aug 17, 2025 - MLB
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Aug 15, 2025 - MLB
Aug 13, 2025 - MLB
Aug 12, 2025 - MLB
Aug 11, 2025 - MLB
4/6 (67%)
2/6 (33%)
Aug 20, 2025 - MLB
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Aug 10, 2025 - MLB
Aug 9, 2025 - MLB
Aug 8, 2025 - MLB

2/6 (33%)
4/6 (67%)
Aug 20, 2025 - MLB
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Aug 17, 2025 - MLB
Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
5/6 (83%)
1/6 (17%)
Aug 20, 2025 - MLB
Aug 19, 2025 - MLB
Aug 18, 2025 - MLB
Aug 10, 2025 - MLB
Aug 9, 2025 - MLB
Aug 8, 2025 - MLB
3/6 (50%)
3/6 (50%)
Aug 17, 2025 - MLB
Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
Aug 14, 2025 - MLB
Aug 13, 2025 - MLB
Aug 12, 2025 - MLB
Cincinnati Reds against Arizona Diamondbacks : Head to Head (H2H)
83 %
17 %
Jun 8, 2025 - MLB
Jun 7, 2025 - MLB
Jun 6, 2025 - MLB
Mar 14, 2025 - MLB Spring Training
Mar 8, 2025 - MLB Spring Training
Feb 27, 2025 - MLB Spring Training
Cincinnati Reds - Arizona Diamondbacks Key Points
- Cincinnati leads the all-time series vs. Arizona 89-87.
- The Red swept the D-backs in Cincinnati earlier in the season.
- Arizona has gone 15-16 since the break, while Cincinnati has gone 17-14.
- Betting Public: 60% of moneyline tickets and 74% of the handle are on the Reds.
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Our Cincinnati Reds vs Arizona Diamondbacks Prediction
I can see why the public is favoring the Reds. They have a solid pitcher on the mound, and the lineup has done a decent job of providing support over the last week, hitting .264 and averaging around four runs across their last five games. However, the D-backs also have a solid pitcher, have been hitting .264 over the last week, and scoring around four runs per game—and they have home field advantage. A win would mean more for the Reds at the moment, but I think Nelson is the better pitcher in this matchup and gives Arizona the edge it needs.
Our Cincinnati vs. Arizona Pick: D-backs ML
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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