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by Lou Aguila in MLB Picks
Two skidding teams get a chance to regain their groove on Tuesday when the Chicago White Sox and the Cleveland Guardians open their three-game series at Progressive Field.
After a 2-2 start, the White Sox have dropped to 2-7 after losing their last five assignments. The White Sox will enter the series vs. the Guardians ranking in the bottom quadrant in batting average (.211), on base percentage (.273), slugging percentage (.344) and total runs.
The Guardians have lost their last two games and four of their last five, crashing to 3-6 in the season. Cleveland falls in the bottom half of the league in terms of batting average (.221) and total runs (34). However, they are playing much worse from the mound, where they have pitched a 5.09 ERA, 1.54 WHIP and .284 BAA.
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Chicago White Sox vs Cleveland Guardians Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
8
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0.581 | 31 | 18 | 13 |
29
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0.258 | 31 | 8 | 23 |
Chicago White Sox and Cleveland Guardians Latest Matches

1/6 (17%)
5/6 (83%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
1/6 (17%)
5/6 (83%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Mar 22, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
Mar 19, 2025 - MLB Spring Training

1/6 (17%)
5/6 (83%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
3/6 (50%)
3/6 (50%)
Mar 22, 2025 - MLB Spring Training
Mar 19, 2025 - MLB Spring Training
Mar 17, 2025 - MLB Spring Training
Mar 14, 2025 - MLB Spring Training
Mar 12, 2025 - MLB Spring Training
Mar 10, 2025 - MLB Spring Training
1/6 (17%)
5/6 (83%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Chicago White Sox against Cleveland Guardians : Head to Head (H2H)
17 %
83 %
Mar 9, 2025 - MLB Spring Training
Feb 27, 2025 - MLB Spring Training
Sep 11, 2024 - MLB
Sep 10, 2024 - MLB
Sep 9, 2024 - MLB
Jul 4, 2024 - MLB
Chicago White Sox - Cleveland Guardians Key Points
- Chicago White Sox are 1-6 SU in their last 7 games against Cleveland.
- Chicago White Sox are 2-9 SU in their last 11 games on the road.
- Cleveland are 1-5 SU in their last 6 games.
- Cleveland are 4-1 SU in their last 5 games against an opponent in the American League Central Division division.
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Our Chicago White Sox vs Cleveland Guardians Prediction
I expect the Guardians to bounce back with better results in this series vs. the White Sox. Cleveland is too good of a team to carry a losing record at 3-6 even this early this season. Of course, they were expected to struggle against the San Deigo Padres, but losing two of the three games they played against the Angles over the weekend didn’t help their cause. After allowing four runs vs. the Padres, Ben Lively gets an opportunity to capture his first win against the White Sox, whom he blanked for two innings in September of last year. Moreover, Cleveland has won six of their previous seven meetings with Chicago, winning by at least two runs six times. Our betting prediction for the Cleveland Guardians vs. Chicago White Sox: Guardians will cover -1.5 runs.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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