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by Lou Aguila in MLB Picks
The San Francisco Giants are expected to march into Thursday’s series finale with the Chicago Cubs as slight -108 home underdogs despite topping the visiting team in the first two games at Oracle Park.
The Giants are making their final push towards postseason qualification with barely four weeks left in the regular season. San Francisco is still three games below .500 at 65-68, but they are just seven games off the current holder of the No.3 wildcard spot in the National League, the 72-61 New York Mets. The Giants have put up strong numbers on both ends in their last five games, pitching a 2.82 ERA and averaging 6.7 runs per game.
Meanwhile, the Cubs’ pitching might have hardly been felt by the Giants in the first two games of this series. Chicago, boasting a 3.84 ERA in the season, surrendered five runs in Game 1 before squandering 12 runs in Game 2. The Cubs’ offensive firepower has noticeably diminished in the series, scoring a total of five runs after two games.
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Chicago Cubs vs San Francisco Giants Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
5
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0.57 | 135 | 77 | 58 |
17
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0.496 | 135 | 67 | 68 |
Chicago Cubs and San Francisco Giants Latest Matches

3/6 (50%)
3/6 (50%)
Aug 27, 2025 - MLB
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Aug 21, 2025 - MLB
4/6 (67%)
2/6 (33%)
Aug 21, 2025 - MLB
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3/6 (50%)
3/6 (50%)
Aug 27, 2025 - MLB
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Aug 14, 2025 - MLB

4/6 (67%)
2/6 (33%)
Aug 27, 2025 - MLB
Aug 26, 2025 - MLB
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Aug 21, 2025 - MLB
3/6 (50%)
3/6 (50%)
Aug 27, 2025 - MLB
Aug 26, 2025 - MLB
Aug 17, 2025 - MLB
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Aug 15, 2025 - MLB
Aug 13, 2025 - MLB
2/6 (33%)
4/6 (67%)
Aug 24, 2025 - MLB
Aug 23, 2025 - MLB
Aug 22, 2025 - MLB
Aug 21, 2025 - MLB
Aug 20, 2025 - MLB
Aug 19, 2025 - MLB
Chicago Cubs against San Francisco Giants : Head to Head (H2H)
17 %
83 %
Aug 27, 2025 - MLB
Aug 26, 2025 - MLB
May 7, 2025 - MLB
May 6, 2025 - MLB
May 5, 2025 - MLB
Mar 9, 2025 - MLB Spring Training
Chicago Cubs - San Francisco Giants Key Points
- Chicago Cubs is 1-4 SU in its last 5 games against San Francisco.
- Chicago Cubs is 1-6 SU in its last 7 games when playing on the road against San Francisco.
- San Francisco is 4-1 SU in its last 5 games.
- San Francisco is 6-1 SU in its last 7 games when playing at home against Chicago Cubs.
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Our Chicago Cubs vs San Francisco Giants Prediction
San Francisco is 6-1 SU in its last 7 games when playing at home against the Chicago Cubs and 4-1 SU in its last 5 games. The Giants will be sending one of their best arms in Logan Webb to the bump on Thursday. Webb is 3-2 with a 2.03 ERA in his last five starts and has recently limited the best offensive team in the National League to one earned run over six innings in a 7-1 win on August 23.
The Chicago Cubs are 1-6 SU in their last 7 games when playing on the road against San Francisco. They are also 1-4 SU in their last five games vs. the Giants. Although Shota Imanaga has maintained a solid 2.81 ERA over his last five starts, Chicago’s 0-4 record against the Giants in their last four games makes it difficult for me to go all-in on them in this very crucial ballgame for both squads.
Our betting prediction for the Chicago Cubs vs. the San Francisco Giants: the Giants will win.
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