San Diego Padres vs Chicago Cubs Prediction & Picks - MLB

USA - MLB

San Diego Padres
9/30/26 22:00
Chicago Cubs

Prediction:

 

The Padres -1.5 runs

+162
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 by Lou Aguila in MLB Picks

The San Diego Padres, listed at +162 to cover -1.5 runs, are riding a huge wave of momentum heading into Game 2 of their wild card series against the Chicago Cubs.

Current Form:

The San Diego Padres will try to close out the Chicago Cubs in Game 2 of their series. The Padres drew first blood in this wild card battle, cruising through an 8-0 win in Game 1. Michael King pitched 7 scoreless innings, while Xander Bogaerts, Manny Machado, and Fernando Tatis Jr. belted a homer each.

The Chicago Cubs’ scoring woes continued following another scoreless game against the Padres. Over the last five games, the Cubs have batted .221 and averaged 2.3 runs. In Game 1, Chicago went 3 for 21 at the plate and reached base only seven times.

Starting Pitchers: Padres RHP Nick Pivetta (3-2, 2.86 ERA) vs. Cubs RHP Kevin Gausman (9-12, 4.51 ERA).

The Matchup: The Padres snapped their five-game losing streak against the Cubs with the Game 1 win on Tuesday.

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San Diego Padres vs Chicago Cubs Form

San Diego Padres and Chicago Cubs Latest Matches

San Diego Padres
San Diego Padres Latest matches
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 29, 2026 - MLB

San Diego Padres
8 :  0
Chicago Cubs

Sep 27, 2026 - MLB

San Diego Padres
9 :  4
Arizona Diamondbacks

Sep 26, 2026 - MLB

San Diego Padres
10 :  7
Arizona Diamondbacks

Sep 25, 2026 - MLB

San Diego Padres
4 :  11
Arizona Diamondbacks

Sep 24, 2026 - MLB

Los Angeles Dodgers
2 :  4
San Diego Padres

Sep 23, 2026 - MLB

Los Angeles Dodgers
1 :  5
San Diego Padres
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 29, 2026 - MLB

San Diego Padres
8 :  0
Chicago Cubs

Sep 27, 2026 - MLB

San Diego Padres
9 :  4
Arizona Diamondbacks

Sep 26, 2026 - MLB

San Diego Padres
10 :  7
Arizona Diamondbacks

Sep 25, 2026 - MLB

San Diego Padres
4 :  11
Arizona Diamondbacks

Sep 20, 2026 - MLB

San Diego Padres
7 :  3
Miami Marlins

Sep 19, 2026 - MLB

San Diego Padres
7 :  6
Miami Marlins
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 24, 2026 - MLB

Los Angeles Dodgers
2 :  4
San Diego Padres

Sep 23, 2026 - MLB

Los Angeles Dodgers
1 :  5
San Diego Padres

Sep 22, 2026 - MLB

Los Angeles Dodgers
7 :  0
San Diego Padres

Sep 17, 2026 - MLB

Colorado Rockies
2 :  9
San Diego Padres

Sep 16, 2026 - MLB

Colorado Rockies
3 :  9
San Diego Padres

Sep 15, 2026 - MLB

Colorado Rockies
9 :  3
San Diego Padres
Chicago Cubs
Chicago Cubs Latest matches
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 29, 2026 - MLB

San Diego Padres
8 :  0
Chicago Cubs

Sep 27, 2026 - MLB

Boston Red Sox
2 :  6
Chicago Cubs

Sep 25, 2026 - MLB

Boston Red Sox
2 :  0
Chicago Cubs

Sep 25, 2026 - MLB

Boston Red Sox
4 :  3
Chicago Cubs

Sep 24, 2026 - MLB

Chicago Cubs
2 :  1
Miami Marlins

Sep 23, 2026 - MLB

Chicago Cubs
2 :  3
Miami Marlins
W L W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 24, 2026 - MLB

Chicago Cubs
2 :  1
Miami Marlins

Sep 23, 2026 - MLB

Chicago Cubs
2 :  3
Miami Marlins

Sep 22, 2026 - MLB

Chicago Cubs
2 :  8
Miami Marlins

Sep 16, 2026 - MLB

Chicago Cubs
8 :  4
Atlanta Braves

Sep 15, 2026 - MLB

Chicago Cubs
3 :  6
Atlanta Braves

Sep 14, 2026 - MLB

Chicago Cubs
7 :  3
Atlanta Braves
W W L L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 29, 2026 - MLB

San Diego Padres
8 :  0
Chicago Cubs

Sep 27, 2026 - MLB

Boston Red Sox
2 :  6
Chicago Cubs

Sep 25, 2026 - MLB

Boston Red Sox
2 :  0
Chicago Cubs

Sep 25, 2026 - MLB

Boston Red Sox
4 :  3
Chicago Cubs

Sep 20, 2026 - MLB

Cincinnati Reds
1 :  9
Chicago Cubs

Sep 19, 2026 - MLB

Cincinnati Reds
2 :  5
Chicago Cubs

San Diego Padres against Chicago Cubs : Head to Head (H2H)

San Diego Padres

17 %

Chicago Cubs

83 %

Sep 29, 2026 - MLB

San Diego Padres
8 :  0
Chicago Cubs

Jul 1, 2026 - MLB

Chicago Cubs
23 :  3
San Diego Padres

Jun 30, 2026 - MLB

Chicago Cubs
9 :  7
San Diego Padres

Jun 29, 2026 - MLB

Chicago Cubs
3 :  2
San Diego Padres

Apr 29, 2026 - MLB

San Diego Padres
4 :  5
Chicago Cubs

Apr 28, 2026 - MLB

San Diego Padres
3 :  8
Chicago Cubs
San Diego Padres vs Chicago Cubs Picks

San Diego Padres - Chicago Cubs Key Points

  1. The Cubs are 4-6 in their last 10 games.
  2. The Cubs average 2.3 runs over their last five games.
  3. The Padres are 8-2 in their last 10 games.
  4. The Padres average 7.5 runs per game over their last five games.
Up to $150 to bet on San Diego Padres - Chicago Cubs! 

Limited Offer. Currently at DraftKings

Our San Diego Padres vs Chicago Cubs Prediction

Key Stats: Aside from averaging nearly 8.0 runs over their last five games, the Padres are sending a red-hot Nick Pivetta to the mound in Game 2.

Pivetta is 5-0 with a stellar 1.25 ERA over his last five starts. The pitcher has surrendered only three runs over his last 22 innings.

What to Expect: The Padres will eliminate the Cubs on Wednesday. San Diego’s decision to send out Pivetta means they want to wrap up the series as quickly as possible.

The offense alone can win this ballgame for the Padres, but Pivetta makes San Diego a delicious option to cover -1.5 runs (+162).

Cubs’ Kevin Gausman has lost his last three starts and posted a 5.27 ERA over his last five mound appearances. By the looks of it, Gausman doesn't have the form to neutralize the Padres’ highly talented batting lineup led by Bogaerts, Machado, and Tatis Jr.

Fearless Forecast: The Padres 8, the Cubs 2

Our betting prediction for the San Diego Padres vs. the Chicago Cubs: The Padres -1.5 Runs

Prediction:

 

The Padres -1.5 runs

+162
$150 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.