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by Lou Aguila in MLB Picks
The Chicago Cubs will go for nothing less than a sweep in Wednesday’s series finale against the Pittsburgh Pirates at PNC Park.
The Cubs, 8-2 in their last 10 games against the Pirates, have received 62 percent of bets to win again (-167 moneyline) in Game 3, according to Covers.com.
Current Form:
The Cubs (87-64) may have already locked up their spot in the wild card series after winning four of their last five games. In this stretch, Chicago has outpitched the competition, sporting a 2.60 ERA and 1.05 WHIP. The offense has remained decent, averaging almost five runs a game (4.6 runs per game) on a .298 batting average.
The Pirates (65-87) have lost four of their last five games and 10 of their last 11 games. Pittsburgh has maintained a competitive 3.82 ERA over a 10-game stretch, a testament to its much-touted pitching prowess. Unfortunately, their lackluster offense continues to be a major problem for the Pirates, who would have achieved contender status had they produced more runs per game this season. The Pirates have only averaged 2.1 runs per game while batting .168 over the last 10 games.
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Chicago Cubs vs Pittsburgh Pirates Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
4
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0.576 | 151 | 87 | 64 |
27
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0.428 | 152 | 65 | 87 |
Chicago Cubs and Pittsburgh Pirates Latest Matches

5/6 (83%)
1/6 (17%)
Sep 16, 2025 - MLB
Sep 15, 2025 - MLB
Sep 14, 2025 - MLB
Sep 13, 2025 - MLB
Sep 12, 2025 - MLB
Sep 10, 2025 - MLB
3/6 (50%)
3/6 (50%)
Sep 14, 2025 - MLB
Sep 13, 2025 - MLB
Sep 12, 2025 - MLB
Sep 7, 2025 - MLB
Sep 6, 2025 - MLB
Sep 5, 2025 - MLB
4/6 (67%)
2/6 (33%)
Sep 16, 2025 - MLB
Sep 15, 2025 - MLB
Sep 10, 2025 - MLB
Sep 9, 2025 - MLB
Sep 8, 2025 - MLB
Aug 31, 2025 - MLB

1/6 (17%)
5/6 (83%)
Sep 16, 2025 - MLB
Sep 15, 2025 - MLB
Sep 14, 2025 - MLB
Sep 13, 2025 - MLB
Sep 12, 2025 - MLB
Sep 11, 2025 - MLB
1/6 (17%)
5/6 (83%)
Sep 16, 2025 - MLB
Sep 15, 2025 - MLB
Sep 7, 2025 - MLB
Sep 6, 2025 - MLB
Sep 5, 2025 - MLB
Sep 4, 2025 - MLB
1/6 (17%)
5/6 (83%)
Sep 14, 2025 - MLB
Sep 13, 2025 - MLB
Sep 12, 2025 - MLB
Sep 11, 2025 - MLB
Sep 10, 2025 - MLB
Sep 9, 2025 - MLB
Chicago Cubs against Pittsburgh Pirates : Head to Head (H2H)
83 %
17 %
Sep 16, 2025 - MLB
Sep 15, 2025 - MLB
Aug 17, 2025 - MLB
Aug 16, 2025 - MLB
Aug 15, 2025 - MLB
Jun 15, 2025 - MLB
Chicago Cubs - Pittsburgh Pirates Key Points
- Chicago Cubs is 6-1 SU in its last 7 games against Pittsburgh.
- Chicago Cubs is 8-1 SU in its last 9 games when playing on the road against Pittsburgh.
- Pittsburgh is 0-5 SU in its last 5 games at home.
- Pittsburgh is 1-10 SU in its last 11 games.
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Our Chicago Cubs vs Pittsburgh Pirates Prediction
At this point, the Cubs have totally crushed the Pirates’ morale after holding them to one run in the last two games. The Cubs are 6-1 in their last 7 games against Pittsburgh and 8-1 in their last 9 games when playing on the road against the same team. Matthew Boyd has pitched to a 5.79 ERA over his last five starts, but he has only surrendered 4 earned runs or an average of 1.3 earned runs per game across his last three starts against the Pirates.
Pirates starter Johan Oviedo has been remarkable lately, posting a 3-2 record with a 3.05 ERA in his last five starts. However, it all goes back again to the Pirates’ inability to provide adequate run support to their starters. Oviedo could come through with stellar numbers on the mound on Wednesday, but all of his effort would mean nothing if the offense cannot drive in enough runs to win a baseball game.
Our betting prediction for the Chicago Cubs vs. the Pittsburgh Pirates: the Cubs -1.5 Runs
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