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by Carlos Zabala in MLB Picks
The Pirates won the second game of the series against the Cubs 4-3, a game marred by an accident involving a fan who fell from the left field wall onto the field but was quickly rescued by Pirates staff.
The Pirates were one of the highest-paying underdogs in MLB betting on Wednesday, with odds of +155, and with this, their chances of an unexpected series win over the Cubs increased considerably. Skenes will be starting Game 3. The right-hander has a 3-2 record with a 2.39 ERA in 37.2 IP, in addition to having struck out 39 and allowed only 4 walks this season.
The 2024 Rookie of the Year is coming off a victory in Los Angeles in what was a good pitching matchup between Skenes and Yamamotto, but Paul prevailed, pitching 6.1 innings and striking out nine Dodgers in his strongest outing of 2025.
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Chicago Cubs vs Pittsburgh Pirates Form
Table
| Teams | % | P | W | L |
|---|---|---|---|---|
|
7
|
0.581 | 31 | 18 | 13 |
|
28
|
0.387 | 31 | 12 | 19 |
Chicago Cubs and Pittsburgh Pirates Latest Matches
4/6 (67%)
2/6 (33%)
Apr 29, 2025 - MLB
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 25, 2025 - MLB
Apr 23, 2025 - MLB
Apr 22, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 25, 2025 - MLB
Apr 23, 2025 - MLB
Apr 22, 2025 - MLB
Apr 20, 2025 - MLB
4/6 (67%)
2/6 (33%)
Apr 29, 2025 - MLB
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 29, 2025 - MLB
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 25, 2025 - MLB
Apr 24, 2025 - MLB
Apr 23, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 29, 2025 - MLB
Apr 20, 2025 - MLB
Apr 19, 2025 - MLB
Apr 18, 2025 - MLB
Apr 17, 2025 - MLB
Apr 16, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 25, 2025 - MLB
Apr 24, 2025 - MLB
Apr 23, 2025 - MLB
Apr 22, 2025 - MLB
Chicago Cubs against Pittsburgh Pirates : Head to Head (H2H)
67 %
33 %
Apr 29, 2025 - MLB
Sep 4, 2024 - MLB
Sep 3, 2024 - MLB
Sep 2, 2024 - MLB
Aug 28, 2024 - MLB
Aug 27, 2024 - MLB
Chicago Cubs - Pittsburgh Pirates Key Points
- Skenes didn't allow an earned run the last time he faced the Cubs in 2024
- Pirates rank third in MLB with 35 stolen bases
- Pirates have a 7-8 record at PNC Park this season
- This is the Cubs' third game against a division rival
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Our Chicago Cubs vs Pittsburgh Pirates Prediction
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