Chicago Cubs vs Pittsburgh Pirates Prediction & Picks - MLB

See our betting tips for the next match between these two teams
Chicago Cubs - Pittsburgh Pirates Betting tips

USA - MLB

Chicago Cubs
4/30/25 18:40
Pittsburgh Pirates

Prediction:

 

Chicago -1.5

-105
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 by Travis Pulver in MLB Picks

The Chicago Cubs will try to keep the good times rolling when they face the Pirates at PNC Park in Pittsburgh. Fans can follow the action once the game gets underway at 6:40 p.m. EST.

Chicago came into yesterday’s game having lost their last two at home to the Phillies. Shota Imanaga got the Cubs off to a solid start, scattering six hits over five innings before giving way to the bullpen. The Pittsburgh lineup managed just one more hit over the last four innings while the Chicago lineup tacked on five more runs to make the final 9-0. The Cubs will look to Matthew Boyd to get the team going today on the mound. Boyd is 2-2 on the season in five starts with a 2.54 ERA and a 1.38 WHIP. He got hit hard by the Dodgers in his last outing (ten hits, one home run across six innings), giving up six runs (three earned), but got plenty of run support from his lineup and got the win. Pittsburgh is scheduled to start Carmen Mlodzinski, who is 1-3 across five starts with a 6.95 ERA and 1.82 WHIP; he has yet to last more than five innings.

Chicago Cubs vs Pittsburgh Pirates Form

Table

Teams % P W L
7
Chicago Cubs
Chicago Cubs
0.581 31 18 13
28
Pittsburgh Pirates
Pittsburgh Pirates
0.387 31 12 19

Chicago Cubs and Pittsburgh Pirates Latest Matches

Chicago Cubs
Chicago Cubs Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 29, 2025 - MLB

Chicago Cubs
9 :  0
Pittsburgh Pirates

Apr 27, 2025 - MLB

Philadelphia Phillies
3 :  1
Chicago Cubs

Apr 26, 2025 - MLB

Philadelphia Phillies
10 :  4
Chicago Cubs

Apr 25, 2025 - MLB

Philadelphia Phillies
0 :  4
Chicago Cubs

Apr 23, 2025 - MLB

Los Angeles Dodgers
6 :  7
Chicago Cubs

Apr 22, 2025 - MLB

Los Angeles Dodgers
10 :  11
Chicago Cubs
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 27, 2025 - MLB

Philadelphia Phillies
3 :  1
Chicago Cubs

Apr 26, 2025 - MLB

Philadelphia Phillies
10 :  4
Chicago Cubs

Apr 25, 2025 - MLB

Philadelphia Phillies
0 :  4
Chicago Cubs

Apr 23, 2025 - MLB

Los Angeles Dodgers
6 :  7
Chicago Cubs

Apr 22, 2025 - MLB

Los Angeles Dodgers
10 :  11
Chicago Cubs

Apr 20, 2025 - MLB

Arizona Diamondbacks
3 :  2
Chicago Cubs
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 29, 2025 - MLB

Chicago Cubs
9 :  0
Pittsburgh Pirates

Apr 16, 2025 - MLB

Chicago Cubs
2 :  4
San Diego Padres

Apr 15, 2025 - MLB

Chicago Cubs
2 :  1
San Diego Padres

Apr 14, 2025 - MLB

Chicago Cubs
4 :  10
San Diego Padres

Apr 13, 2025 - MLB

Chicago Cubs
4 :  2
Los Angeles Dodgers

Apr 12, 2025 - MLB

Chicago Cubs
16 :  0
Los Angeles Dodgers
Pittsburgh Pirates
Pittsburgh Pirates Latest matches
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 29, 2025 - MLB

Chicago Cubs
9 :  0
Pittsburgh Pirates

Apr 27, 2025 - MLB

Pittsburgh Pirates
2 :  9
Los Angeles Dodgers

Apr 26, 2025 - MLB

Pittsburgh Pirates
4 :  8
Los Angeles Dodgers

Apr 25, 2025 - MLB

Pittsburgh Pirates
3 :  0
Los Angeles Dodgers

Apr 24, 2025 - MLB

Pittsburgh Pirates
3 :  4
Los Angeles Angels

Apr 23, 2025 - MLB

Pittsburgh Pirates
3 :  0
Los Angeles Angels
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 29, 2025 - MLB

Chicago Cubs
9 :  0
Pittsburgh Pirates

Apr 20, 2025 - MLB

Cleveland Guardians
5 :  4
Pittsburgh Pirates

Apr 19, 2025 - MLB

Cleveland Guardians
3 :  0
Pittsburgh Pirates

Apr 18, 2025 - MLB

Cleveland Guardians
10 :  7
Pittsburgh Pirates

Apr 17, 2025 - MLB

Washington Nationals
0 :  1
Pittsburgh Pirates

Apr 16, 2025 - MLB

Washington Nationals
1 :  6
Pittsburgh Pirates
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 27, 2025 - MLB

Pittsburgh Pirates
2 :  9
Los Angeles Dodgers

Apr 26, 2025 - MLB

Pittsburgh Pirates
4 :  8
Los Angeles Dodgers

Apr 25, 2025 - MLB

Pittsburgh Pirates
3 :  0
Los Angeles Dodgers

Apr 24, 2025 - MLB

Pittsburgh Pirates
3 :  4
Los Angeles Angels

Apr 23, 2025 - MLB

Pittsburgh Pirates
3 :  0
Los Angeles Angels

Apr 22, 2025 - MLB

Pittsburgh Pirates
9 :  3
Los Angeles Angels

Chicago Cubs against Pittsburgh Pirates : Head to Head (H2H)

Chicago Cubs

67 %

Pittsburgh Pirates

33 %

Apr 29, 2025 - MLB

Chicago Cubs
9 :  0
Pittsburgh Pirates

Sep 4, 2024 - MLB

Pittsburgh Pirates
0 :  12
Chicago Cubs

Sep 3, 2024 - MLB

Pittsburgh Pirates
5 :  0
Chicago Cubs

Sep 2, 2024 - MLB

Pittsburgh Pirates
5 :  3
Chicago Cubs

Aug 28, 2024 - MLB

Chicago Cubs
14 :  10
Pittsburgh Pirates

Aug 27, 2024 - MLB

Chicago Cubs
9 :  5
Pittsburgh Pirates

Chicago Cubs - Pittsburgh Pirates Key Points

  1. The Cubs are 4-0 when favored on the road.
  2. The Pirates are 3-4 when underdogs at home.
  3. The public is getting behind the Cubs to win outright with 91% of moneyline tickets and 93% of the handle on Chicago.
  4. Betting Splits: 91% of total tickets and 91% of the handle are on the OVER (8.5)

Our Chicago Cubs vs Pittsburgh Pirates Prediction

Mathew Boyd has handled the Pirates in the past, and I see no reason to think he can’t do so again today. Pittsburgh has struggled to generate offense against lefties, and they can’t count on Mlodzinski to keep the Cubs lineup in check.

Our Cubs vs. Pirates Pick: Chicago -1.5

Prediction:

 

Chicago -1.5

-105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Chicago Cubs vs Pittsburgh Pirates Picks