USA - NCAA
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by Travis Pulver in NCAA Picks
The Charlotte 49ers will head out onto the road for the first time this season when they head down to southern Florida to take on the USF Bulls at Raymond James Stadium in Tampa, FL. Gametime for this American Athletic Conference opener for both teams is set to kick off at 7 p.m. EST on Friday, Oct. 3.
Charlotte will certainly have its hands full facing a USF team that opened the season against three ranked teams, beating two of them. The Bulls dominated No. 25 Boise State in their season opener, 34-7, before winning a close one against No. 13 Florida, 18-16. But the following week saw them come back down to Earth after getting manhandled by Miami, 49-12. They dominated South Carolina State 63-14 before last week’s bye. The Bulls are not exceptional on either side of the ball, but good on both, ranked No. 55 in offensive (31.8 ppg) and defensive (21.5 ppg allowed) scoring. As for the 49ers, Charlotte opened the season with a four-game homestand and went 1-3 while scoring 31 total points in all three losses. They struggle to run the ball, averaging 88.3 yards per game, but aren’t bad at passing it (258.3 yards per game). The 49ers are scoring 18.3 ppg while allowing 29.3.
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Charlotte 49ers vs South Florida Bulls Form
Table
Teams | % | P | W | D | L |
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8
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0 | 0 | 0 | 0 | 0 |
10
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0 | 1 | 0 | 0 | 1 |
Charlotte 49ers and South Florida Bulls Latest Matches

3/6 (50%)
0/6 (0%)
3/6 (50%)
Sep 18, 2025 - NCAA
Sep 13, 2025 - NCAA
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Aug 29, 2025 - NCAA
Nov 30, 2024 - NCAA
Nov 23, 2024 - NCAA
2/6 (33%)
0/6 (0%)
4/6 (67%)
Sep 18, 2025 - NCAA
Sep 13, 2025 - NCAA
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Aug 29, 2025 - NCAA
Nov 30, 2024 - NCAA
Nov 16, 2024 - NCAA
1/3 (33%)
0/3 (0%)
2/3 (67%)
Nov 23, 2024 - NCAA
Oct 26, 2024 - NCAA
Oct 19, 2024 - NCAA

4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 20, 2025 - NCAA
Sep 13, 2025 - NCAA
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Aug 28, 2025 - NCAA
Dec 24, 2024 - NCAA Division I, FBS, Playoffs
Nov 30, 2024 - NCAA
4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 20, 2025 - NCAA
Aug 28, 2025 - NCAA
Nov 23, 2024 - NCAA
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Oct 12, 2024 - NCAA
4/6 (67%)
0/6 (0%)
2/6 (33%)
Sep 13, 2025 - NCAA
Sep 6, 2025 - NCAA
Dec 24, 2024 - NCAA Division I, FBS, Playoffs
Nov 30, 2024 - NCAA
Nov 16, 2024 - NCAA
Nov 1, 2024 - NCAA
Charlotte 49ers against South Florida Bulls : Head to Head (H2H)
Nov 16, 2024 - NCAA
Charlotte 49ers - South Florida Bulls Key Points
- USF and Charlotte have played twice; the Bulls won both games in dominant fashion, 48-14 and 59-24.
- Both teams were on a bye last week.
- Betting Public: 92% of moneyline tickets and 78% of the handle are on USF.
- Betting Public: TOTAL tickets are split with roughly 50% taking the OVER and 50% taking the UNDER. But 66% of the handle is on the OVER and 34% the UNDER.
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Our Charlotte 49ers vs South Florida Bulls Prediction
South Florida is not a great team like Miami, but they are a solid, good overall team without a glaring, easy-to-exploit weakness. At least not one that a team like Charlotte could take advantage of. Charlotte ranks amongst the lower third of college football teams in many significant categories, and over No. 100 in quite a few. They have some promising players on both sides of the ball, but not enough to be competitive vs. USF.
Our Charlotte vs. USF Pick: USF -27.5
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